Patents by Inventor Frank Grawe

Frank Grawe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050239197
    Abstract: The invention relates to a lid element which is placed on cell culture vessels in which cells contained in a liquid medium are accommodated. The lid element according to the invention is intended to allow determination of metabolism activities of cells which are contained in the cell culture vessels, by means of optical measurement methods, which can be carried out with simple handling by means of laboratory personnel. Light-guiding elements are provided on the lid element which can be fitted to the cell culture vessel and, when the lid element is fitted, project into the interior of cavities in the cell vessel. At least one optically sensitive layer is formed on one end surface and/or on the outer envelope surface of the light-guiding elements, which are preferably optical waveguides in the form of rods, for detection of chemical substance concentrations which change within the cavities.
    Type: Application
    Filed: January 24, 2003
    Publication date: October 27, 2005
    Applicant: 02-Scan GmbH
    Inventors: Andreas Katerkamp, Uwe Brinkmann, Frank Grawe, Goran Key, Sabine Schreiber, Jochen Uckelmann
  • Publication number: 20040035792
    Abstract: The invention relates to a device and a method for separating undissolved constituents out of biological fluids, especially for separating blood plasma out of whole blood. It is to propose a simple and cost-effective way by means of which undissolved constituents can be separated out of biological fluids, in particular blood plasma out of whole blood, and the pure fluid is presenting then as a pure liquid volume without any substrate. To solve this object, e.g., whole blood is placed into a feed chamber. The feed chamber is isolated in an all-over manner by means of a membrane from a per se closed cavity having a small height. The cavity is connected to a flow channel or an opening from which the/the separated blood plasma can be removed.
    Type: Application
    Filed: August 27, 2003
    Publication date: February 26, 2004
    Inventors: Peter R Rauch, Andreas Katerkamp, Marco Schmitz, Frank Grawe
  • Patent number: 6440748
    Abstract: The invention concerns a device and a method for carrying out fluorescence immunoassays, wherein from at least one light source light is directed onto a surface at one end of a light waveguide and with the light coupled into the light waveguide by evanescent field excitation at the surface of the light waveguide fluorescence of at least one labelling substance bound to a chemical or biochemical partner of a general receptor-ligand system is excited. The solution according to the invention is here to provide a possible way of carrying out fluorescence immunoassays with high accuracy of measurement at low cost and within a short time. To achieve this object, the fluorescent light is decoupled from the light waveguide and directed via an optical system onto an optical detector with which the intensity of the fluorescent light is measured.
    Type: Grant
    Filed: July 18, 2000
    Date of Patent: August 27, 2002
    Assignee: Institut für Chemo- und Biosensorik Münster E.V.
    Inventors: Andreas Katerkamp, Ulrich Kunz, Frank Grawe, Göran Key