Patents by Inventor Frank Hacker

Frank Hacker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130211060
    Abstract: The present invention relates to a hydroxyalkyl starch conjugate and a method for preparing the same, said hydroxy-yalkyl starch conjugate comprising a hydroxyalkyl starch derivative and a cytotoxic agent, the cytotoxic agent comprising at least one secondary hydroxyl group, wherein the hydroxyalkyl starch is linked via said secondary hydroxyl group to the cytotoxic agent. The conjugate according to the present invention has a structure according to the following formula HAS?(-L-M)n wherein M is a residue of the cytotoxic agent, L is a linking moiety, HAS? is the residue of the hydroxyalkyl starch derivative, and n is greater than or equal to 1, and wherein the hydroxyalkyl starch derivative has a mean molecular weight (MW) above the renal threshold.
    Type: Application
    Filed: July 11, 2011
    Publication date: August 15, 2013
    Applicant: Fresenius Kabi Deutschland GmbH
    Inventors: Helmut Knoller, Dominik Heckmann, Frank Hacker, Norbert Zander, Frank Nocken, Saswata Lahiri, Nitin Gupta, Sunil Sanghani, Azim Abul, Hemant Kumar Singh, Sandeep Grewal, Sandeep Kaur
  • Patent number: 8494753
    Abstract: An internal combustion engine can be operated by a fuel mixture consisting of a base fuel and an alternative fuel. Concentration values (ETH_PERC) of the alternative fuel are determined in at least two different ways for operating the internal combustion engine. A reliable concentration value of the alternative fuel is determined depending on the various determined concentration values (ETH_PERC).
    Type: Grant
    Filed: December 10, 2008
    Date of Patent: July 23, 2013
    Assignee: Continental Automotive GmbH
    Inventors: Frank Hacker, Gerhard Haft
  • Patent number: 8364377
    Abstract: In a method and a device which allow determination of the combustion lambda value of an internal combustion engine having at least two combustion chambers without using a lambda sensor, a predetermined first fuel quantity is metered to the first combustion chamber and a predetermined second fuel quantity is metered to the second combustion chamber, the first fuel quantity is reduced by a predetermined amount and the second fuel quantity is increased by the same predetermined amount. A first engine noise, associated with the first combustion chamber, and a second engine noise, associated with the second combustion chamber, are determined. The combustion lambda value is determined based on the first engine noise value and second engine noise value.
    Type: Grant
    Filed: March 20, 2008
    Date of Patent: January 29, 2013
    Assignee: Continental Automotive GmbH
    Inventors: Frank Hacker, Gerhard Haft
  • Patent number: 8024108
    Abstract: The individual cylinders of the internal combustion engine are divided into at least two cylinder banks wherein each is assigned a separate exhaust-gas channel. Secondary air is conveyed by a compressor. The flow of the secondary-air mass flow is set independently by an electrically controllable throughflow control. A value for the entire secondary-air mass flow is determined from the signal of a secondary-air mass sensor. The throughflow control is controlled into an open position, the value for the entire secondary-air mass flow is detected and subsequently the throughflow control is controlled into a closed position, the values for the secondary-air mass flows are detected before and after closure, and these values are compared with a plurality of different threshold values and, as a function of the result of the comparisons, a determination is made of the fault location with regard to the respective cylinder bank.
    Type: Grant
    Filed: November 9, 2006
    Date of Patent: September 20, 2011
    Assignee: Continental Automotive GmbH
    Inventor: Frank Hacker
  • Patent number: 7941266
    Abstract: In a method for controlling an internal combustion engine (1) for a motor vehicle in stop-start operation, the internal combustion engine (1) is operated in the idling operating state. If there is a request for switch-off of the internal combustion engine (1) the torque produced by the internal combustion engine (1) is reduced while fuel continues to be injected. The fuel injection is switched off if the speed of the internal combustion engine (1) reaches a predetermined minimum value. The torque produced by the internal combustion engine (1) is increased again if the request for switching off the internal combustion engine (1) is canceled before the minimum speed is reached.
    Type: Grant
    Filed: December 10, 2008
    Date of Patent: May 10, 2011
    Assignee: Continental Automotive GmbH
    Inventors: Klaus Bayerle, Frank Hacker
  • Publication number: 20100312458
    Abstract: An internal combustion engine can be operated by a fuel mixture consisting of a base fuel and an alternative fuel. Concentration values (ETH_PERC) of the alternative fuel are determined in at least two different ways for operating the internal combustion engine. A reliable concentration value of the alternative fuel is determined depending on the various determined concentration values (ETH_PERC).
    Type: Application
    Filed: December 10, 2008
    Publication date: December 9, 2010
    Inventors: Frank Hacker, Gerhard Haft
  • Publication number: 20100222981
    Abstract: The individual cylinders of the internal combustion engine are divided into at least two cylinder banks wherein each is assigned a separate exhaust-gas channel. Secondary air is conveyed by a compressor. The flow of the secondary-air mass flow is set independently by an electrically controllable throughflow control. A value for the entire secondary-air mass flow is determined from the signal of a secondary-air mass sensor. The throughflow control is controlled into an open position, the value for the entire secondary-air mass flow is detected and subsequently the throughflow control is controlled into a closed position, the values for the secondary-air mass flows are detected before and after closure, and these values are compared with a plurality of different threshold values and, as a function of the result of the comparisons, a determination is made of the fault location with regard to the respective cylinder bank.
    Type: Application
    Filed: November 9, 2006
    Publication date: September 2, 2010
    Applicant: CONTINENTAL AUTOMOTIVE GMBH
    Inventor: Frank Hacker
  • Publication number: 20100138135
    Abstract: In a method and a device which allow determination of the combustion lambda value of an internal combustion engine having at least two combustion chambers without using a lambda sensor, a predetermined first fuel quantity is metered to the first combustion chamber and a predetermined second fuel quantity is metered to the second combustion chamber, the first fuel quantity is reduced by a predetermined amount and the second fuel quantity is increased by the same predetermined amount. A first engine noise, associated with the first combustion chamber, and a second engine noise, associated with the second combustion chamber, are determined. The combustion lambda value is determined based on the first engine noise value and second engine noise value.
    Type: Application
    Filed: March 20, 2008
    Publication date: June 3, 2010
    Inventors: Frank Hacker, Gerhard Haft
  • Publication number: 20090157284
    Abstract: In a method for controlling an internal combustion engine (1) for a motor vehicle in stop-start operation, the internal combustion engine (1) is operated in the idling operating state. If there is a request for switch-off of the internal combustion engine (1) the torque produced by the internal combustion engine (1) is reduced while fuel continues to be injected. The fuel injection is switched off if the speed of the internal combustion engine (1) reaches a predetermined minimum value. The torque produced by the internal combustion engine (1) is increased again if the request for switching off the internal combustion engine (1) is canceled before the minimum speed is reached.
    Type: Application
    Filed: December 10, 2008
    Publication date: June 18, 2009
    Inventors: Klaus Bayerle, Frank Hacker
  • Patent number: 7293444
    Abstract: A bending apparatus for rod-shaped and tubular workpieces, includes a rotatable bending mandrel with a bending groove is provided with a wrinkle smoothener, which immediately precedes the bending mandrel, and two sliding jaws. In order to change the bending direction around the bending mandrel, the sliding jaws can be moved to the other side thereof. In doing so, the sliding jaw on the side of the bending mandrel is arranged freely rotatable on a support axis, which extends parallel to the axis of rotation of the bending mandrel and whose position relative to the bending mandrel can be shifted parallel to the feeding direction of the workpiece. The sliding jaw is provided such that the end of its forming groove facing towards the bending mandrel can be placed in contact with the bending groove by shifting the support axis and, thus, its forming groove tangentially joins said groove.
    Type: Grant
    Filed: March 7, 2006
    Date of Patent: November 13, 2007
    Assignee: WAFIOS Aktiengesellschaft
    Inventors: Frank Hacker, Werner Maier, Patrik Schlund, Jürgen Wolf, Dietmar Sautter
  • Patent number: 7234333
    Abstract: On a machine for bending rod-shaped or tubular workpieces, which includes a bending head having a bending mandrel mounted on a rotational axis and rotatable by means of a rotary drive, and having a clamping device for pressing the workpiece to be bent against a forming groove on the bending mandrel and also a feeding device for the workpiece to be processed, whereby the clamping device is positionable relative to the bending mandrel and can is also pivotable concentrically to the rotational axis of the bending mandrel, the clamping device is attached to two mutually independent rotary drives, one of which performs its pivoting movement about the rotational axis of the bending mandrel, and via the other of which it can be moved with respect to the bending mandrel by using an interposed conversion transmission that converts a rotary motion to a linear motion, whereby the bending head includes three concentrically nested rotary shafts for transmitting the drive of the three rotary drives to the bending mandrel,
    Type: Grant
    Filed: March 23, 2005
    Date of Patent: June 26, 2007
    Assignee: Wafios Aktiengesellschaft
    Inventors: Werner Maier, Jurgen Wolf, Frank Hacker, Patrick Schlund, Dieter Geisel, Dietmar Sautter
  • Publication number: 20060201219
    Abstract: A bending apparatus for rod-shaped and tubular workpieces, includes a rotatable bending mandrel with a bending groove is provided with a wrinkle smoothener, which immediately precedes the bending mandrel, and two sliding jaws. In order to change the bending direction around the bending mandrel, the sliding jaws can be moved to the other side thereof. In doing so, the sliding jaw on the side of the bending mandrel is arranged freely rotatable on a support axis, which extends parallel to the axis of rotation of the bending mandrel and whose position relative to the bending mandrel can be shifted parallel to the feeding direction of the workpiece. The sliding jaw is provided such that the end of its forming groove facing towards the bending mandrel can be placed in contact with the bending groove by shifting the support axis and, thus, its forming groove tangentially joins said groove.
    Type: Application
    Filed: March 7, 2006
    Publication date: September 14, 2006
    Inventors: Frank Hacker, Werner Maier, Patrik Schlund, Jurgen Wolf, Dietmar Sautter
  • Patent number: 6973777
    Abstract: The internal combustion engine has at least two partly separate exhaust systems in each of which are disposed a catalytic converter, and upstream thereof, a lambda probe. There is provided a secondary air pump and a number of individual secondary air lines, corresponding to the number of exhaust systems, for delivering secondary air to the respective exhaust systems. From the signal of at least one air mass meter, a value is determined for the total air mass flow introduced into the exhaust systems. In order to determine the air mass actually introduced into the individual exhaust systems, the output signals from the lambda probes in the exhaust systems are used to identify an uneven distribution of the air mass fed to the individual exhaust systems.
    Type: Grant
    Filed: August 11, 2003
    Date of Patent: December 13, 2005
    Assignee: Siemens Aktiengellschaft
    Inventors: Klaus Bayerle, Frank Hacker, Hong Zhang
  • Publication number: 20050210945
    Abstract: On a machine for bending rod-shaped or tubular workpieces, which includes a bending head having a bending mandrel mounted on a rotational axis and rotatable by means of a rotary drive, and having a clamping device for pressing the workpiece to be bent against a forming groove on the bending mandrel and also a feeding device for the workpiece to be processed, whereby the clamping device is positionable relative to the bending mandrel and can is also pivotable concentrically to the rotational axis of the bending mandrel, the clamping device is attached to two mutually independent rotary drives, one of which performs its pivoting movement about the rotational axis of the bending mandrel, and via the other of which it can be moved with respect to the bending mandrel by using an interposed conversion transmission that converts a rotary motion to a linear motion, whereby the bending head includes three concentrically nested rotary shafts for transmitting the drive of the three rotary drives to the bending mandrel,
    Type: Application
    Filed: March 23, 2005
    Publication date: September 29, 2005
    Inventors: Werner Maier, Jurgen Wolf, Frank Hacker, Patrick Schlund, Dieter Geisel, Dietmar Sautter
  • Patent number: 6877354
    Abstract: To balance ozone sensors for the onboard diagnosis of a catalytic element which is arranged in a vehicle and is exposed to an ambient airstream, for breaking down ozone, predetermined enable conditions allowing the sensor balancing to be carried out are checked, and if the enable conditions are fulfilled the values of the output signals from the ozone sensors are recorded and compared with one another. This comparison gives a deviation value which is characteristic of the deviation between the two values, and the deviation value is used to decide whether sensor balancing is required and indeed possible. If sensor balancing is required and possible, the values of the output signals from the ozone sensors are compared with a threshold value and depending on the result of this comparison either an additive or a multiplicative correction of the values of the output signals is performed.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: April 12, 2005
    Assignee: Siemens Aktiengesellschaft
    Inventors: Klaus Bayerle, Frank Hacker, Hong Zhang
  • Publication number: 20040107693
    Abstract: The internal combustion engine has at least two partly separate exhaust systems in each of which are disposed a catalytic converter, and upstream thereof, a lambda probe. There is provided a secondary air pump and a number of individual secondary air lines, corresponding to the number of exhaust systems, for delivering secondary air to the respective exhaust systems. From the signal of at least one air mass meter, a value is determined for the total air mass flow introduced into the exhaust systems. In order to determine the air mass actually introduced into the individual exhaust systems, the output signals from the lambda probes in the exhaust systems are used to identify an uneven distribution of the air mass fed to the individual exhaust systems.
    Type: Application
    Filed: August 11, 2003
    Publication date: June 10, 2004
    Inventors: Klaus Bayerle, Frank Hacker, Hong Zhang
  • Patent number: 6684629
    Abstract: Method for checking the conversion capacity of a catalytic element for converting ozone where the catalytic element is provided as a vehicle radiator with a catalytic coating and the method of checking uses ozone sensors upstream and downstream of the radiator. The check is only carried out if predetermined enable conditions are satisfied. Only then are the values emitted by the sensors recorded and compared with one another. A variable which represents an uncorrected value for the quality of the conversion capacity is derived from this comparison. This variable is weighted as a function of at least one operating parameter of the vehicle. The weighted variable is compared with a predetermined threshold value, and, if the threshold value is exceeded, it is concluded that the conversion capacity of the radiator is insufficient.
    Type: Grant
    Filed: October 1, 2002
    Date of Patent: February 3, 2004
    Assignee: Siemens Aktiengesellschaft
    Inventors: Klaus Bayerle, Frank Hacker, Hong Zhang
  • Publication number: 20030131650
    Abstract: To balance ozone sensors for the onboard diagnosis of a catalytic element which is arranged in a vehicle and is exposed to an ambient airstream, for breaking down ozone, predetermined enable conditions allowing the sensor balancing to be carried out are checked, and if the enable conditions are fulfilled the values of the output signals from the ozone sensors are recorded and compared with one another. This comparison gives a deviation value which is characteristic of the deviation between the two values, and the deviation value is used to decide whether sensor balancing is required and indeed possible. If sensor balancing is required and possible, the values of the output signals from the ozone sensors are compared with a threshold value and depending on the result of this comparison either an additive or a multiplicative correction of the values of the output signals is performed.
    Type: Application
    Filed: December 20, 2002
    Publication date: July 17, 2003
    Inventors: Klaus Bayerle, Frank Hacker, Hong Zhang
  • Publication number: 20030093990
    Abstract: Method for checking the conversion capacity of a catalytic element for converting ozone where the catalytic element is provided as a vehicle radiator with a catalytic coating and the method of checking uses ozone sensors upstream and downstream of the radiator. The check is only carried out if predetermined enable conditions are satisfied. Only then are the values emitted by the sensors recorded and compared with one another. A variable which represents an uncorrected value for the quality of the conversion capacity is derived from this comparison. This variable is weighted as a function of at least one operating parameter of the vehicle. The weighted variable is compared with a predetermined threshold value, and, if the threshold value is exceeded, it is concluded that the conversion capacity of the radiator is insufficient.
    Type: Application
    Filed: October 1, 2002
    Publication date: May 22, 2003
    Inventors: Klaus Bayerle, Frank Hacker, Hong Zhang
  • Patent number: 6155043
    Abstract: By taking into account the deviation between a desired value, determined from a model for a secondary-air mass flow and an actual value of the secondary-air mass flow, detected by an airflow sensor, a correction value is obtained. From the correction value, together with a main-air mass flow that is present in an intake tract of the internal combustion engine and a pilot control value for an air/fuel ratio, a correction factor for correcting an injection duration is derived.
    Type: Grant
    Filed: June 30, 1999
    Date of Patent: December 5, 2000
    Assignee: Siemens Aktiengesellschaft
    Inventors: Hong Zhang, Frank Hacker