Patents by Inventor Frank Hofmann

Frank Hofmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240117068
    Abstract: The present invention concerns antigen binding proteins specifically binding melanoma associated antigen A (MAGE-A) protein-derived antigens. The invention in particular provides antigen binding proteins which specifically bind to the MAGE-A antigenic peptide comprising or consisting of SEQ ID NO: 1 in a complex with a major histocombatibility (MHC) protein. The antigen binding proteins of the invention contain, in particular, the complementary determining regions (CDRs) of novel engineered T cell receptors (TCRs) that specifically bind to said MAGE-A peptide/MHC complex. The antigen binding proteins of the invention are of use for the diagnosis, treatment and prevention of MAGE-A expressing cancerous diseases. Further provided are nucleic acids encoding the antigen binding proteins of the invention, vectors comprising these nucleic acids, recombinant cells expressing the antigen binding proteins and pharmaceutical compositions comprising the antigen binding proteins of the invention.
    Type: Application
    Filed: December 13, 2023
    Publication date: April 11, 2024
    Inventors: Meike HUTT, Felix UNVERDORBEN, Sebastian BUNK, Dominik MAURER, Martin HOFMANN, Gabriele PSZOLLA, Sara YOUSEF, Claudia WAGNER, Frank SCHWOEBEL, Heiko SCHUSTER
  • Publication number: 20240107355
    Abstract: There is provided an apparatus in a user equipment, the apparatus comprising including: one or more processors, and memory storing instructions that, when executed by the one or more processors, cause the apparatus to: perform measurements on signals received from a target network entity, wherein the user equipment is connected to a serving network entity and calculate a variance of the measurements over a time period. The one or more processors, and memory storing instructions, when executed by the one or more processors, further cause the apparatus to, in response to determining that the calculated variance is above a threshold value, adjust the transmission of a measurement report from the user equipment.
    Type: Application
    Filed: February 3, 2021
    Publication date: March 28, 2024
    Inventors: Sandra Hofmann, Jeroen WIGARD, Frank FREDERIKSEN
  • Publication number: 20240092933
    Abstract: The present invention concerns antigen binding proteins directed against PRAME protein-derived antigens. The invention in particular provides antigen binding proteins which are specific for the tumor expressed antigen PRAME, wherein the tumor antigen comprises or consists of SEQ ID NO: 50 and is in a complex with a major histocompatibility complex (MHC) protein. The antigen binding proteins of the invention contain, in particular, the complementary determining regions (CDRs) of novel engineered T cell receptors (TCRs) that specifically bind to said PRAME peptide. The antigen binding proteins of the invention are for use in the diagnosis, treatment and prevention of PRAME expressing cancerous diseases. Further provided are nucleic acids encoding the antigen binding proteins of the invention, vectors comprising said nucleic acids, recombinant cells expressing the antigen binding proteins and pharmaceutical compositions comprising the antigen binding proteins of the invention.
    Type: Application
    Filed: November 16, 2023
    Publication date: March 21, 2024
    Inventors: Gabriele PSZOLLA, Martin HOFMANN, Meike HUTT, Sebastian BUNK, Felix UNVERDORBEN, Frank SCHWOEBEL, Dominik MAURER, Maike JAWORSKI, Claudia WAGNER, Florian SCHWOERER, Heiko SCHUSTER
  • Publication number: 20240087445
    Abstract: A method for providing an object message about an object, recognized in surroundings of a road user, in a communication network for communicating with other road users. The road user includes a sensor system for detecting the surroundings and an evaluation unit for evaluating sensor data generated by the sensor system and transferring object messages via the communication network. The method includes: receiving sensor data, generated by the sensor system, in the evaluation unit; recognizing at least one object in the surroundings of the road user based on the sensor data, a movement parameter and a further object parameter being ascertained; calculating an object transfer priority; determining, based on the object transfer priority, whether the recognized object is to be included in an object message; and, if so, generating the object message including the recognized object, and sending the object message via the wireless communication network.
    Type: Application
    Filed: September 22, 2020
    Publication date: March 14, 2024
    Inventors: Ignacio Llatser Marti, Florian Alexander Schiegg, Frank Hofmann, Maxim Dolgov, Florian Wildschuette, Hendrik Fuchs, Thomas Michalke
  • Patent number: 11854392
    Abstract: A method for an apparatus operating in a wireless communication network. The method includes: determining at least one functional safety indicator that indicates at least whether associated data, especially V2X data that comprises at least one of a vehicle operating parameter and a roadway event, or industrial data that comprises a machine operating parameter, or building technology data that comprises building operational data, is relevant according to at least one safety integrity level; and transmitting the data along with the at least one determined functional safety indicator.
    Type: Grant
    Filed: April 8, 2022
    Date of Patent: December 26, 2023
    Assignee: ROBERT BOSCH GMBH
    Inventors: Frank Hofmann, Khaled Shawky Hassan, Kurt Eckert, Tobias Frye
  • Publication number: 20230319867
    Abstract: Methods and apparatuses for radio communication. The method comprises: transmitting first information that characterizes at least one quality associated with a downlink channel received by a radio terminal; and transmitting second information that characterizes a present or future environmental situation of a physical entity that is associated with the radio terminal.
    Type: Application
    Filed: March 23, 2023
    Publication date: October 5, 2023
    Inventors: Maximilian Stark, Hugues Narcisse Tchouankem, Khaled Shawky Hassan, Frank Hofmann, Oscar Dario Ramos Cantor
  • Publication number: 20230302725
    Abstract: A method for additively printing extension segments on workpieces using an additive manufacturing machine includes controlling, with a computing system, an operation of a print head of the machine such that a region of interest of a build plate of the machine is scanned with an electromagnetic radiation beam. Additionally, the method includes receiving, with the computing system, data associated with reflections of the beam off of the build plate as the region interest is scanned. Furthermore, the method includes receiving, with the computing system, data associated with a location of the beam relative to the build plate. Moreover, the method includes determining, with the computing system, a location of a workpiece interface based on the received data. In addition, the method includes controlling, with the computing system, the operation of the print head such that an extension segment is additively printed on the determined workpiece interface.
    Type: Application
    Filed: May 18, 2023
    Publication date: September 28, 2023
    Applicant: General Electric Company
    Inventors: Xiaolei Shi, Jinjie Shi, Joseph Edward Hampshire, Douglas Frank Hofmann, Pinghai Yang
  • Patent number: 11691336
    Abstract: A method for additively printing extension segments on workpieces using an additive manufacturing machine includes controlling, with a computing system, an operation of a print head of the machine such that a region of interest of a build plate of the machine is scanned with an electromagnetic radiation beam. Additionally, the method includes receiving, with the computing system, data associated with reflections of the beam off of the build plate as the region interest is scanned. Furthermore, the method includes receiving, with the computing system, data associated with a location of the beam relative to the build plate. Moreover, the method includes determining, with the computing system, a location of a workpiece interface based on the received data. In addition, the method includes controlling, with the computing system, the operation of the print head such that an extension segment is additively printed on the determined workpiece interface.
    Type: Grant
    Filed: November 11, 2020
    Date of Patent: July 4, 2023
    Assignee: General Electric Company
    Inventors: Xiaolei Shi, Jinjie Shi, Joseph Edward Hampshire, Douglas Frank Hofmann, Pinghai Yang
  • Publication number: 20230182848
    Abstract: A method for operating a control unit of a light-weight vehicle, especially of a pedal electric cycle or of an electric kick scooter. The method includes: receiving at least one sensor information associated with a sensor of the vehicle; and transmitting, via a communication channel between the control unit and a personal mobile terminal, the at least one sensor information and/or at least an information based thereon.
    Type: Application
    Filed: September 23, 2021
    Publication date: June 15, 2023
    Inventors: Khaled Shawky Hassan, Nadia Brahmi, Andre Schwarzmeier, Frank Hofmann, Andreas Schaller
  • Publication number: 20230169851
    Abstract: A method for communicating between a motor vehicle and an infrastructure. The method includes: ascertaining a requirement vector for at least one function to be carried out with the aid of the motor vehicle and/or the infrastructure, the requirement vector indicating which characteristics of a communication link between the motor vehicle and the infrastructure should simultaneously be satisfied for an execution of the function; ascertaining a communication state, which indicates which communication possibilities exist for a communication link between the motor vehicle and the infrastructure; ascertaining a radio channel between the motor vehicle and the infrastructure based on the requirement vector and based on the ascertained communication state; establishing a communication link between the motor vehicle and the infrastructure using the ascertained radio channel to carry out the at least one function using the established communication link.
    Type: Application
    Filed: November 23, 2022
    Publication date: June 1, 2023
    Inventors: Kurt Eckert, Frank Hofmann, Tobias Frye
  • Patent number: 11627637
    Abstract: A first road-side network node for operating in a cell-supported radio communications network and for operating in an adhoc radio communications network is provided. Data is exchanged with at least a second road-side network node via a sidelink radio channel of the cell-supported radio communications network. Data is exchanged with at least a third road-side network node via an adhoc radio channel of the adhoc radio communications network.
    Type: Grant
    Filed: September 19, 2018
    Date of Patent: April 11, 2023
    Assignee: Robert Bosch GmbH
    Inventors: Frank Hofmann, Kurt Eckert
  • Publication number: 20230091438
    Abstract: An apparatus configured to generate a relay transmission to a second radio node based on observing a transmission attempt from a first radio node. The apparatus includes a radio interface configured to receive data comprising radio channel observations of the environment and to generate data comprising radio transmissions for transmission into the environment, a monitoring interface configured to receive data characterising the physical state of the environment, and a processor communicatively coupled to the radio interface and the monitoring interface. The processor is configured to: update a model characterising the environment occupied by the first radio node and the second radio node; observe an indication of an attempt of the first radio node to communicate with the second radio node; initiate the relaying of the attempt of the first radio node to communicate with the second radio node.
    Type: Application
    Filed: August 25, 2022
    Publication date: March 23, 2023
    Applicants: Robert Bosch GmbH, Robert Bosch GmbH
    Inventors: Christoph Thein, Frank Hofmann
  • Patent number: 11570645
    Abstract: A first roadside network unit is provided. A first transceiver for a first wireless communication network is designed to receive data from a second wireless network unit on a first channel of the first wireless communication network. A processor is designed to provide the received data to a second transceiver for transmission to a third roadside network unit. The second transceiver for a second wireless communication network is designed to transmit the data provided by the processor to the third roadside network unit on a second channel of the second communication network.
    Type: Grant
    Filed: June 11, 2018
    Date of Patent: January 31, 2023
    Assignee: Robert Bosch GmbH
    Inventors: Jean-Philippe Kermoal, Frank Hofmann, Kurt Eckert
  • Publication number: 20220392341
    Abstract: A method for providing a maneuver message for coordinating a maneuver between a road user and at least one further road user in a communication network. The method includes: receiving the communication data and/or the sensor data in the evaluation unit; determining a possible trajectory of the road user based on the communication data and/or the sensor data, at least one trajectory parameter describing a property of the possible trajectory being ascertained; calculating a trajectory transfer priority from the trajectory parameter, the trajectory transfer priority representing a relevance of the at least one possible trajectory for the road user and/or the further road user; determining, based on the trajectory transfer priority, whether the at least one possible trajectory is to be included in a maneuver message; if so: generating the maneuver message including the at least one possible trajectory, and sending the maneuver message via the communication network.
    Type: Application
    Filed: September 25, 2020
    Publication date: December 8, 2022
    Inventors: Florian Alexander Schiegg, Ignacio Llatser Marti, Frank Hofmann, Florian Wildschuette, Hendrik Fuchs, Maxim Dolgov, Thomas Michalke
  • Patent number: 11522624
    Abstract: A method is described for the locationally selective transmission of a signal by radio. Both a transmitter and a receiver are synchronized to the same time reference. The receiver receiving and demodulating, at a time that is one of the specified times of the time reference, a signal transmitted by the transmitter, if the receiver has received the signal at a time that is one of the specified times. The method includes the transmitter determining a receive location within a receive zone to which it wishes to transmit the signal in selective fashion, a position in the receive zone being a function of a position of the transmitter and a signal runtime. The method also includes the transmitter transmitting the signal; and the receiver, which is situated inside the receive zone, receives and demodulates the signal.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: December 6, 2022
    Assignee: Robert Bosch GmbH
    Inventors: Christoph Thein, Klaus Sambale, Frank Hofmann
  • Publication number: 20220378061
    Abstract: The invention provides a method of treating a beverage ingredient extract comprising the steps of: a. filtering a beverage ingredient extract to obtain a beverage ingredient extract retentate and a beverage ingredient extract permeate; b. raising the pH of said beverage ingredient extract retentate to provide a treated beverage ingredient extract retentate; and c. combining said treated beverage ingredient extract retentate with said beverage ingredient extract permeate to generate a recombined ingredient extract.
    Type: Application
    Filed: December 18, 2020
    Publication date: December 1, 2022
    Inventors: Gertjan Heijman, Rebecca Van Der Westen Skogvold, Thomas Frank Hofmann, Oliver Frank, Michael Josef Gigl
  • Publication number: 20220386169
    Abstract: A method for transferring a message in a communications network for communication between a road user and at least one further road user. The road user and the further road user each include an evaluation unit for transferring messages via the communications network. The method includes: receiving a first message in the evaluation unit, the first message including message segments, each including a priority value; determining an instantaneous capacity utilization of the communications network; filtering message segments to be transferred out of the first message, based on the priority values and the instantaneous capacity utilization of the communications network; and generating a second message including the message segments to be transferred, and sending the second message via the communications network.
    Type: Application
    Filed: September 25, 2020
    Publication date: December 1, 2022
    Inventors: Ignacio Llatser Marti, Florian Alexander Schiegg, Frank Hofmann, Maxim Dolgov, Florian Wildschuette, Hendrik Fuchs, Thomas Michalke
  • Publication number: 20220369088
    Abstract: A method for an apparatus operating in a wireless communication network. The method includes transmitting a plurality of functional safety containers offset in time along with at least one associated functional safety indicator that indicates a relevance according to at least one safety integrity level, wherein at least one of the plurality of functional safety containers comprises data, especially V2x data that comprises at least one of a vehicle operating parameter and a roadway event, or industrial data that comprises a machine operating parameter, or building technology data that comprises building operational data.
    Type: Application
    Filed: April 7, 2022
    Publication date: November 17, 2022
    Inventors: Frank Hofmann, Khaled Shawky Hassan, Kurt Eckert, Tobias Frye
  • Publication number: 20220358839
    Abstract: A method for an apparatus operating in a wireless communication network. The method includes: determining at least one functional safety indicator that indicates at least whether associated data, especially V2X data that comprises at least one of a vehicle operating parameter and a roadway event, or industrial data that comprises a machine operating parameter, or building technology data that comprises building operational data, is relevant according to at least one safety integrity level; and transmitting the data along with the at least one determined functional safety indicator.
    Type: Application
    Filed: April 8, 2022
    Publication date: November 10, 2022
    Inventors: Frank Hofmann, Khaled Shawky Hassan, Kurt Eckert, Tobias Frye
  • Publication number: 20220345856
    Abstract: A method for data transfer in a V2X communication network (V2X: vehicle-to-everything). A communication control module for an at least semi-automated vehicle is further provided, which is designed to carry out the method for data transfer. The data transfer in the V2X communication network takes place with the aid of V2X messages, which are coded by a sender and decoded by at least one receiver. A V2X message includes in each case a piece of context information about surroundings of the sender and/or of the receiver with respect to a vehicle and/or to an object and/or to a person. The piece of context information 505 is utilized for each V2X message for validation of the V2X message and/or for reduction of a packet size of the V2X message.
    Type: Application
    Filed: April 13, 2022
    Publication date: October 27, 2022
    Inventors: Tobias Frye, Frank Hofmann, Kurt Eckert