Abstract: The present invention concerns antigen binding proteins specifically binding melanoma associated antigen A (MAGE-A) protein-derived antigens. The invention in particular provides antigen binding proteins which specifically bind to the MAGE-A antigenic peptide comprising or consisting of SEQ ID NO: 1 in a complex with a major histocombatibility (MHC) protein. The antigen binding proteins of the invention contain, in particular, the complementary determining regions (CDRs) of novel engineered T cell receptors (TCRs) that specifically bind to said MAGE-A peptide/MHC complex. The antigen binding proteins of the invention are of use for the diagnosis, treatment and prevention of MAGE-A expressing cancerous diseases. Further provided are nucleic acids encoding the antigen binding proteins of the invention, vectors comprising these nucleic acids, recombinant cells expressing the antigen binding proteins and pharmaceutical compositions comprising the antigen binding proteins of the invention.

Abstract: A method for an apparatus operating in a wireless communication network. The method includes transmitting a plurality of functional safety containers offset in time along with at least one associated functional safety indicator that indicates a relevance according to at least one safety integrity level, wherein at least one of the plurality of functional safety containers comprises data, especially V2x data that comprises at least one of a vehicle operating parameter and a roadway event, or industrial data that comprises a machine operating parameter, or building technology data that comprises building operational data.

Abstract: The disclosure provides novel personalized therapies, kits, transmittable forms of information and methods for use in treating patients having cancer, wherein the cancer is amenable to therapeutic treatment with an inhibitor, e.g., an inhibitor of any of the targets disclosed herein. Kits, methods of screening for candidate inhibitors, and associated methods of treatment are also provided.

Abstract: A method for providing a maneuver message for coordinating a maneuver between a road user and at least one further road user in a communication network. The method includes: receiving the communication data and/or the sensor data in the evaluation unit; determining a possible trajectory of the road user based on the communication data and/or the sensor data, at least one trajectory parameter describing a property of the possible trajectory being ascertained; calculating a trajectory transfer priority from the trajectory parameter, the trajectory transfer priority representing a relevance of the at least one possible trajectory for the road user and/or the further road user; determining, based on the trajectory transfer priority, whether the at least one possible trajectory is to be included in a maneuver message; if so: generating the maneuver message including the at least one possible trajectory, and sending the maneuver message via the communication network.

Abstract: A method for transferring a message in a communications network for communication between a road user and at least one further road user. The road user and the further road user each include an evaluation unit for transferring messages via the communications network. The method includes: receiving a first message in the evaluation unit, the first message including message segments, each including a priority value; determining an instantaneous capacity utilization of the communications network; filtering message segments to be transferred out of the first message, based on the priority values and the instantaneous capacity utilization of the communications network; and generating a second message including the message segments to be transferred, and sending the second message via the communications network.

Abstract: There is provided a method comprising: determining at least one V2X message (M) comprising at least one data container (DSC) comprising at least one environment image (I #1) representing a part (E #1) of an environment in at least one spatial dimension at one point in time; and wireless transmitting the at least one V2X message (M).

Abstract: A treatment machine comprises a chamber for the treatment of one substrate or a plurality of substrates. A rotatably supported temperature-controlled shaft (30) defines a cylindrical, gas-tight hollow space. A heating arrangement (40, 50) is provided for electrically heating at least a part of the shaft (30) arranged in the chamber. The heating arrangement (40, 50) comprises an accommodation mandrel (40) for accommodating at least one electrical heating element (50), said accommodation mandrel (40) being arranged in a non-rotating manner and extending into the hollow space of the shaft (30). An outer surface of the accommodation mandrel (40) is spaced apart from an inner surface of the shaft (30) by a gap.

Abstract: A method for an apparatus operating in a wireless communication network. The method includes transmitting a plurality of functional safety containers offset in time along with at least one associated functional safety indicator that indicates a relevance according to at least one safety integrity level, wherein at least one of the plurality of functional safety containers comprises data, especially V2x data that comprises at least one of a vehicle operating parameter and a roadway event, or industrial data that comprises a machine operating parameter, or building technology data that comprises building operational data.

Abstract: A method for additively printing extension segments on workpieces using an additive manufacturing machine includes controlling, with a computing system, an operation of a print head of the machine such that a region of interest of a build plate of the machine is scanned with an electromagnetic radiation beam. Additionally, the method includes receiving, with the computing system, data associated with reflections of the beam off of the build plate as the region interest is scanned. Furthermore, the method includes receiving, with the computing system, data associated with a location of the beam relative to the build plate. Moreover, the method includes determining, with the computing system, a location of a workpiece interface based on the received data. In addition, the method includes controlling, with the computing system, the operation of the print head such that an extension segment is additively printed on the determined workpiece interface.

Abstract: A method for radio communication, especially according to an estimation support mode. The method includes monitoring at least one downlink channel; determining at least one downlink channel quality associated with the monitored at least one downlink channel; determining, based at least on the at least one monitored downlink channel quality, at least one future downlink channel quality indicator that characterizes an estimated future quality associated with the downlink channel; determining, based at least on the at least one monitored downlink channel quality, at least one estimation quality indicator that characterizes an estimation quality of the at least one associated future downlink channel indicator; transmitting the at least one estimation quality indicator; and transmitting the at least one future downlink channel quality indicator.

Abstract: Method for safeguarding a communication between a first vehicle 3 and a second vehicle 4, wherein the first vehicle 3 has a first communication device and the second vehicle 4 has a second communication device, wherein the first vehicle 3 forms a leading vehicle and the second vehicle 4 forms a following vehicle, wherein data are interchanged between the first communication device and the second communication device by way of a wireless communication connection, wherein the communication connection has a transmission quality, wherein a future transmission quality is estimated and/or determined for the communication connection, wherein if the future transmission quality is below a minimum transmission quality then a countermeasure to improve the transmission quality is performed.

Abstract: A method for providing an object message about an object, recognized in surroundings of a road user, in a communication network for communicating with other road users. The road user includes a sensor system for detecting the surroundings and an evaluation unit for evaluating sensor data generated by the sensor system and transferring object messages via the communication network. The method includes: receiving sensor data, generated by the sensor system, in the evaluation unit; recognizing at least one object in the surroundings of the road user based on the sensor data, a movement parameter and a further object parameter being ascertained; calculating an object transfer priority; determining, based on the object transfer priority, whether the recognized object is to be included in an object message; and, if so, generating the object message including the recognized object, and sending the object message via the wireless communication network.

Abstract: A method for an apparatus operating in a wireless communication network. The method includes: determining at least one functional safety indicator that indicates at least whether associated data, especially V2X data that comprises at least one of a vehicle operating parameter and a roadway event, or industrial data that comprises a machine operating parameter, or building technology data that comprises building operational data, is relevant according to at least one safety integrity level; and transmitting the data along with the at least one determined functional safety indicator.

Abstract: Methods and apparatuses for radio communication. The method comprises: transmitting first information that characterizes at least one quality associated with a downlink channel received by a radio terminal; and transmitting second information that characterizes a present or future environmental situation of a physical entity that is associated with the radio terminal.

Abstract: A method for additively printing extension segments on workpieces using an additive manufacturing machine includes controlling, with a computing system, an operation of a print head of the machine such that a region of interest of a build plate of the machine is scanned with an electromagnetic radiation beam. Additionally, the method includes receiving, with the computing system, data associated with reflections of the beam off of the build plate as the region interest is scanned. Furthermore, the method includes receiving, with the computing system, data associated with a location of the beam relative to the build plate. Moreover, the method includes determining, with the computing system, a location of a workpiece interface based on the received data. In addition, the method includes controlling, with the computing system, the operation of the print head such that an extension segment is additively printed on the determined workpiece interface.

Abstract: A method for additively printing extension segments on workpieces using an additive manufacturing machine includes controlling, with a computing system, an operation of a print head of the machine such that a region of interest of a build plate of the machine is scanned with an electromagnetic radiation beam. Additionally, the method includes receiving, with the computing system, data associated with reflections of the beam off of the build plate as the region interest is scanned. Furthermore, the method includes receiving, with the computing system, data associated with a location of the beam relative to the build plate. Moreover, the method includes determining, with the computing system, a location of a workpiece interface based on the received data. In addition, the method includes controlling, with the computing system, the operation of the print head such that an extension segment is additively printed on the determined workpiece interface.

Abstract: A method for operating a control unit of a light-weight vehicle, especially of a pedal electric cycle or of an electric kick scooter. The method includes: receiving at least one sensor information associated with a sensor of the vehicle; and transmitting, via a communication channel between the control unit and a personal mobile terminal, the at least one sensor information and/or at least an information based thereon.

Abstract: A method for communicating between a motor vehicle and an infrastructure. The method includes: ascertaining a requirement vector for at least one function to be carried out with the aid of the motor vehicle and/or the infrastructure, the requirement vector indicating which characteristics of a communication link between the motor vehicle and the infrastructure should simultaneously be satisfied for an execution of the function; ascertaining a communication state, which indicates which communication possibilities exist for a communication link between the motor vehicle and the infrastructure; ascertaining a radio channel between the motor vehicle and the infrastructure based on the requirement vector and based on the ascertained communication state; establishing a communication link between the motor vehicle and the infrastructure using the ascertained radio channel to carry out the at least one function using the established communication link.

Abstract: A first road-side network node for operating in a cell-supported radio communications network and for operating in an adhoc radio communications network is provided. Data is exchanged with at least a second road-side network node via a sidelink radio channel of the cell-supported radio communications network. Data is exchanged with at least a third road-side network node via an adhoc radio channel of the adhoc radio communications network.

Abstract: An apparatus configured to generate a relay transmission to a second radio node based on observing a transmission attempt from a first radio node. The apparatus includes a radio interface configured to receive data comprising radio channel observations of the environment and to generate data comprising radio transmissions for transmission into the environment, a monitoring interface configured to receive data characterising the physical state of the environment, and a processor communicatively coupled to the radio interface and the monitoring interface. The processor is configured to: update a model characterising the environment occupied by the first radio node and the second radio node; observe an indication of an attempt of the first radio node to communicate with the second radio node; initiate the relaying of the attempt of the first radio node to communicate with the second radio node.