Patents by Inventor Frank-Holm RÖGNER
Frank-Holm RÖGNER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11802271Abstract: The present invention relates to a method for irradiating a population of mammalian cells comprising at least one target mammalian cell with electron beams and/or X-rays, characterized in that: (i) a composition comprising a population of mammalian cells is irradiated in vitro with electron beams and/or X-rays, the population of mammalian cells containing at least one target mammalian cell and the dose rate being within the range from 5 Gy/sec to 107 Gy/sec, and (ii) optionally viable target mammalian cells are isolated or enriched from the population of mammalian cells, and to agents obtainable thereby and to uses thereof.Type: GrantFiled: March 14, 2018Date of Patent: October 31, 2023Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.Inventors: Frank-Holm Rögner, Sebastian Ulbert, Jana Burkhardt, Javier Portillo, Jessy Schönfelder
-
Publication number: 20230010204Abstract: Apparatuses and methods are provided for applying accelerated electrons to a gaseous medium by means of an electron beam generator, which has at least one cathode for emitting electrons and at least one electron exit window, wherein a) the at least one cathode is annular and the at least one electron exit window is in the form of an annular first hollow cylinder, the annular electron exit window in the form of the first hollow cylinder forms an inner wall of an annular housing of the electron beam generator, wherein the electrons emitted by the cathode are accelerated to the ring axis of the annular housing; b) an annular second hollow cylinder is arranged within the electron exit window in the form of the first hollow cylinder and delimits an annular space between the first hollow cylinder and the second hollow cylinder; c) a cooling gas is fed through the annular space between the first hollow cylinder and the second hollow cylinder; and d) the gaseous medium to which accelerated electrons are to be appliedType: ApplicationFiled: December 14, 2020Publication date: January 12, 2023Applicant: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.Inventors: Gösta MATTAUSCH, André WEIDAUER, Ralf BLÜTHNER, Jörg KUBUSCH, Frank-Holm RÖGNER, Volker KIRCHHOFF, Rainer LABITZKE, Burkhard ZIMMERMANN
-
Patent number: 10980903Abstract: Methods and Apparatus are provided for irradiating a liquid with accelerated electrons. The liquid is prepared. The liquid is mixed with particles having at least one luminescent substance, where the particles are formed such that the particles are dispersed in the liquid after mixing. The liquid is irradiated with an electromagnetic radiation, which induces the at least one luminescent substance to luminesce. An actual value of a physical quantity characterizing the luminescence of the luminescent substance is detected. The liquid is irradiated with accelerated electrons until the detected actual value corresponds to a target value.Type: GrantFiled: June 8, 2017Date of Patent: April 20, 2021Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.Inventors: Jessy Schönfelder, Frank-Holm Rögner, Javier Portillo Casado, Jörg Kubusch
-
Patent number: 10806018Abstract: An apparatus is provided for generating accelerated electrons, including a housing; an inlet for supplying a working gas; at least one first cathode; and at least one first anode, between which a corona discharge plasma can be generated. Ions from the corona discharge plasma can be accelerated onto the surface of a second cathode. Electrons emitted by the second cathode can be accelerated in the direction of the electron exit window by means of a second electric voltage applied between the second cathode and a second anode. The housing, the second cathode, and the electron exit window are ring-shaped. The ring-shaped space is divided into ring segments. Each ring segment has at least one wire-shaped electrode, which extends through the ring segment. At least one separate power supply device is associated with each ring segment, by means of which the strength of the electrical current is adjustable.Type: GrantFiled: March 2, 2018Date of Patent: October 13, 2020Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.Inventors: André Weidauer, Frank-Holm Rögner, Gösta Mattausch, Ralf Blüthner, Ignacio Gabriel Vicente Gabas, Jörg Kubusch
-
Publication number: 20200102539Abstract: The present invention relates to a method for irradiating a population of mammalian cells comprising at least one target mammalian cell with electron beams and/or X-rays, characterized in that: (i) a composition comprising a population of mammalian cells is irradiated in vitro with electron beams and/or X-rays, the population of mammalian cells containing at least one target mammalian cell and the dose rate being within the range from 5 Gy/sec to 107 Gy/sec, and (ii) optionally viable target mammalian cells are isolated or enriched from the population of mammalian cells, and to agents obtainable thereby and to uses thereof.Type: ApplicationFiled: March 14, 2018Publication date: April 2, 2020Applicant: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.Inventors: FRANK-HOLM RÖGNER, SEBASTIAN ULBERT, JANA BURKHARDT, JAVIER PORTILLO, JESSY SCHÖNFELDER
-
Publication number: 20190387605Abstract: An apparatus is provided for generating accelerated electrons, including a housing; an inlet for supplying a working gas; at least one first cathode; and at least one first anode, between which a corona discharge plasma can be generated. Ions from the corona discharge plasma can be accelerated onto the surface of a second cathode. Electrons emitted by the second cathode can be accelerated in the direction of the electron exit window by means of a second electric voltage applied between the second cathode and a second anode. The housing, the second cathode, and the electron exit window are ring-shaped. The ring-shaped space is divided into ring segments. Each ring segment has at least one wire-shaped electrode, which extends through the ring segment. At least one separate power supply device is associated with each ring segment, by means of which the strength of the electrical current is adjustable.Type: ApplicationFiled: March 2, 2018Publication date: December 19, 2019Applicant: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.Inventors: André Weidauer, Frank-Holm Rögner, Gösta Mattausch, Ralf Blüthner, Ignacio Gabriel Vicente Gabas, Jörg Kubusch
-
Publication number: 20190175769Abstract: Methods and Apparatus are provided for irradiating a liquid with accelerated electrons. The liquid is prepared. The liquid is mixed with particles having at least one luminescent substance, where the particles are formed such that the particles are dispersed in the liquid after mixing. The liquid is irradiated with an electromagnetic radiation, which induces the at least one luminescent substance to luminesce. An actual value of a physical quantity characterizing the luminescence of the luminescent substance is detected. The liquid is irradiated with accelerated electrons until the detected actual value corresponds to a target value.Type: ApplicationFiled: June 8, 2017Publication date: June 13, 2019Applicant: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.Inventors: Jessy SCHÖNFELDER, Frank-Holm RÖGNER, Javier PORTILLO CASADO, Jörg KUBUSCH
-
Patent number: 9949425Abstract: An apparatus includes at least one electron beam generator for generating accelerated electrons with which bulk material particles are impingeable during free fall. The electron beam generator has an annular design in which the electrons are emitted and accelerated by an annular cathode. The electrons exit from an electron outlet window in the direction of the ring axis. The annular electron beam generator is arranged in such a way that the ring axis of the electron beam generator is oriented perpendicular to, or at an angle of up to 45° from the horizontal. The apparatus may further include a device for separating bulk material particles arranged above the annular electron beam generator, the bottom wall of said device having at least one opening out of which the bulk material particles fall and, from there, fall through the ring which is formed by the electron beam generator.Type: GrantFiled: November 12, 2014Date of Patent: April 24, 2018Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.Inventors: Frank-Holm Rögner, André Weidauer, Gösta Mattausch, Jörg Kubusch
-
Publication number: 20170236692Abstract: A plasma generation process that is more optimized for vapor deposition processes in general, and particularly for directed vapor deposition processing. The features of such an approach enables a robust and reliable coaxial plasma capability in which the plasma jet is coaxial with the vapor plume, rather than the orthogonal configuration creating the previous disadvantages. In this way, the previous deformation of the vapor gas jet by the work gas stream of the hollow cathode pipe can be avoided and the carrier gas consumption needed for shaping the vapor plume can be significantly decreased.Type: ApplicationFiled: April 28, 2017Publication date: August 17, 2017Applicant: University of Virginia Patent FoundationInventors: Haydn N. G. Wadley, Goesta Mattausch, Henry Morgner, Frank-Holm Roegner
-
Publication number: 20170175246Abstract: Methods are provided for production of a composite layer comprising a plastic foil and a layer deposited directly thereon. A method for production of a composite layer comprising a plastic foil and at least one layer deposited directly onto the plastic foil by means of chemical gas-phase deposition within a vacuum chamber may be provided, wherein the plastic foil has a proportion of at least 20 percent by mass of a metal element or of a semiconductor element, wherein during the layer deposition, at least one monomer is supplied into the vacuum chamber and a plasma is formed within the vacuum chamber. After completed deposition of the layer, at least one surface region of the layer is exposed to accelerated electrons.Type: ApplicationFiled: November 21, 2016Publication date: June 22, 2017Inventors: Hendrik Drese, John Fahlteich, Wolfgang Schwarz, Frank-Holm Rögner, Nicolas Schiller
-
Patent number: 9640369Abstract: A plasma generation process that is more optimized for vapor deposition processes in general, and particularly for directed vapor deposition processing. The features of such an approach enables a robust and reliable coaxial plasma capability in which the plasma jet is coaxial with the vapor plume, rather than the orthogonal configuration creating the previous disadvantages. In this way, the previous deformation of the vapor gas jet by the work gas stream of the hollow cathode pipe can be avoided and the carrier gas consumption needed for shaping the vapor plume can be significantly decreased.Type: GrantFiled: February 24, 2010Date of Patent: May 2, 2017Assignee: University of Virginia Patent FoundationInventors: Haydn N. G. Wadley, Goesta Mattausch, Henry Morgner, Frank-Holm Roegner
-
Publication number: 20160374261Abstract: An apparatus includes at least one electron beam generator for generating accelerated electrons with which bulk material particles are impingeable during free fall. The electron beam generator has an annular design in which the electrons are emitted and accelerated by an annular cathode. The electrons exit from an electron outlet window in the direction of the ring axis. The annular electron beam generator is arranged in such a way that the ring axis of the electron beam generator is oriented perpendicular to, or at an angle of up to 45° from the horizontal. The apparatus may further include a device for separating bulk material particles arranged above the annular electron beam generator, the bottom wall of said device having at least one opening out of which the bulk material particles fall and, from there, fall through the ring which is formed by the electron beam generator.Type: ApplicationFiled: November 12, 2014Publication date: December 29, 2016Inventors: Frank-Holm RÖGNER, André WEIDAUER, Gösta MATTAUSCH, Jörg KUBUSCH
-
Patent number: 8232443Abstract: Method and device for inactivating a microbiologically contaminated mass containing solid particles. The method includes mixing the mass containing solid particles with a gelatinizing agent, transporting the mixed mass of solid particles and gelatinizing agent through a shaping device structured so that the mixed mass, at least in one area, is shaped to form a lamellar volume with a layer thickness of between 1 mm and 3 mm, and impinging the formed lamellar volume of the mixed mass with accelerated electrons.Type: GrantFiled: June 15, 2009Date of Patent: July 31, 2012Assignees: Fraunhoffer-Gesellschaft zur Foerderung der Angewandten Forschung E.V., Glatt Ingenieurtechnik GmbH, Glatt Systemtechnik GmbHInventors: Olaf Roeder, Henrik Flaske, Christiane Wetzel, Frank-Holm Roegner, Wolfgang Prahl, Ralf Kretzschmar, Thomas Wegner, Reinhard Boeber
-
Publication number: 20110318498Abstract: A plasma generation process that is more optimized for vapor deposition processes in general, and particularly for directed vapor deposition processing. The features of such an approach enables a robust and reliable coaxial plasma capability in which the plasma jet is coaxial with the vapor plume, rather than the orthogonal configuration creating the previous disadvantages. In this way, the previous deformation of the vapor gas jet by the work gas stream of the hollow cathode pipe can be avoided and the carrier gas consumption needed for shaping the vapor plume can be significantly decreased.Type: ApplicationFiled: February 24, 2010Publication date: December 29, 2011Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATIONInventors: Haydn N.G. Wadley, Goesta Mattausch, Henry Morgner, Frank-Holm Roegner
-
Publication number: 20100130805Abstract: Method and device for inactivating a microbiologically contaminated mass containing solid particles. The method includes mixing the mass containing solid particles with a gelatinizing agent, transporting the mixed mass of solid particles and gelatinizing agent through a shaping device structured so that the mixed mass, at least in one area, is shaped to form a lamellar volume with a layer thickness of between 1 mm and 3 mm, and impinging the formed lamellar volume of the mixed mass with accelerated electrons.Type: ApplicationFiled: June 15, 2009Publication date: May 27, 2010Applicants: FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V., GLATT INGENIEURTECHNIK GMBH, GLATT SYSTEMTECHNIK GMBHInventors: Olaf ROEDER, Dipl.-lng. Henrik FLASKE, Christiane WETZEL, Dipl.-Phys. Frank-Holm ROEGNER, Wolfgang PRAHL, Ralf KRETZSCHMAR, Thomas WEGNER, Reinhard BOEBER