Abstract: Disclosed is a method for sequencing a nucleotide sequence of a target nucleic acid. The method comprises: providing a pool of amplicons, wherein the pool of amplicons is prepared by attaching a unique identifier to the target nucleic acid, and amplifying by PCR the target nucleic acid to which the unique identifier is attached; and sequencing the amplicons comprising the unique identifier and the target nucleic acid. In the method, a nucleotide sequence of the unique identifier comprises both a random nucleotide (N) and a predetermined nucleotide.

Abstract: Disclosed is a method for sequencing a nucleotide sequence of a target nucleic acid. The method comprises: providing a pool of amplicons, wherein the pool of amplicons is prepared by attaching a unique identifier to the target nucleic acid, and amplifying by PCR the target nucleic acid to which the unique identifier is attached; and sequencing the amplicons comprising the unique identifier and the target nucleic acid. In the method, a nucleotide sequence of the unique identifier comprises both a random nucleotide (N) and a predetermined nucleotide.

Abstract: Provided herein are methods for the detection of genetic mutations associated with cancer, particularly in the KIT gene.

Abstract: Provided herein are methods for the detection of genetic mutations associated with cancer, particularly in the KIT gene.

Abstract: Resins obtainable from compounds of formula 1 in which the substituents R2 and HNR1 can be in the ortho, meta or para position relative to one another, and R1 has the same meaning as R2, or has the meaning —COR2, where R1 is independent of R2, R2 is C1-C30-alkyl, C2-C30-alkenyl, C6-C18-aryl, C7-C30-alkylaryl, by the steps, which can be carried out in any order, of A) reaction with an aldehyde of the formula 2 R3—CHO  (2), wherein R3 is H, C1-C30-alkyl, C2-C30-alkenyl, C6-C18-aryl or C7-C30-alkylaryl, and B) alkoxylation with a C2-C4-alkylene oxide in molar excess, such that the resulting alkoxylate has a degree of alkoxylation of from 1 to 100 alkylene oxide units per —NH group, and the resin has a molecular weight of from 250 to 100,000 units, and their use as emulsion breakers.

Abstract: Resins useful in methods of breaking oil-water emulsions. The resins obtained by reacting a compound of formula 1 with an aldehyde and alkoxylating, in any order: wherein X is —NHR1; —COOH; or —CONHR2; and is ortho—, meta— or para— to X and is a radical of —O—R3; —C(O)R4; —OC(O)R5; —NR6R7; wherein R1-R7 values are defined herein.

Abstract: The present invention relates to resins obtainable from compounds of the formula 1 1

Abstract: The present invention relates to resins obtained by reacting a compound of formula 1 with an aldehyde and alkoxylating, in any order: wherein X is —OH, Y is ortho-, meta- or para- to X and is a radical of formula 4, wherein R5 is a C1-C30-alkyl, C2-C30-alkenyl, C6-C18-aryl, or C7-C30-alkylaryl. The resin has a molecular mass from 250 to 100,000 and is useful in methods of breaking oil-water emulsions.

Abstract: The invention relates to an additive for inhibiting gas hydrate formation, containing a) from 5 to 90% by weight of 2-isobutoxyethanol, b) from 5 to 60% by weight of a copolymer which has structural units which are derived from maleic acid, maleic anhydride or derivatives of maleic acid or of maleic anhydride, and c) at least 10% by weight of water or a monohydric or polyhydric alcohol, except the 2-isobutoxyethanol, or mixtures of the stated substances, based on the total weight of the additive, the sum of the contents of compounds a) and b) being from 10 to 90% by weight, and a process for inhibiting gas hydrate formation using 2-isobutoxyethanol.