Patents by Inventor Frank Holzer

Frank Holzer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240216484
    Abstract: The present invention addresses the problem of indicating active-ingredient classes which can treat virus diseases caused by coronaviruses in a human or animal. Said treatment includes the acute treatment of an already existing virus disease and the prophylaxis of same. The present invention relates to a bromelain protease, bromelain, jacalin-like lectin, extract from the stem and/or the fruit of a pineapple plant, combination preparation, bromelain protease inhibitor, protein/protease mix, and glycated bromelain protein formed by exogenous non-enzymatic glycation, for use in the treatment or prophylaxis of virus infections caused by coronaviruses in a human or animal.
    Type: Application
    Filed: June 10, 2021
    Publication date: July 4, 2024
    Applicants: URSAPHARM ARZNEIMITTEL GMBH, HOCHSCHULE KAISERSLAUTERN, HELMHOLTZ-INSTITUT FÜR PHARMAZEUTISCHE FORSCHUNG SAARLAND
    Inventors: Peter GROSS, Rolf MÜLLER, Frank HOLZER, Peter MEISER, Holger SEELERT
  • Publication number: 20240165219
    Abstract: The present invention relates to an immunogenic or vaccine composition against SARS-CoV-2, for use thereof in treatment of Covid-19, characterized in that it is administered on the ocular mucosa and/or the urogenital mucosa.
    Type: Application
    Filed: March 22, 2022
    Publication date: May 23, 2024
    Applicant: EYE VACC
    Inventors: Norbert Schrage, Frank Holzer, Joël Blomet, Daniel Desmecht
  • Patent number: 11518571
    Abstract: The present invention relates to a dispensing head (1) for a dispensing device, and to a dispensing device (100) for the metered dispensing of liquid preparations, which dispensing device is provided with the dispensing head. The dispensing head comprises a special valve (6), which comprises at least one sealing lip (7a, 7b), by means of which a passage channel (3) for dispensing the liquid preparation, which passage channel is formed in the dispensing head, can be closed. The present invention is characterized by the simplicity of the dispensing head (1) and the economic advantages in the manufacturing which are linked to this simplicity.
    Type: Grant
    Filed: April 1, 2019
    Date of Patent: December 6, 2022
    Assignee: F. HOLZER GMBH
    Inventors: Hyeck-Hee Lee, Ute Steinfeld, Markus Mahler, Frank Holzer
  • Patent number: 11221248
    Abstract: Disclosed is a pump head with a specially configured elastic valve which enables secure closure of the pump head. It is ensured by the valve that complete emptying and, at the same time, secure closing of the pump head is ensured so that no residues of fluid to be metered remain in the storage state of the pump head. In addition, the present invention relates to a metering device which can be configured for example as squeeze bottle, as non-airless system or as airless system, the metering device comprising a pump head according to the invention.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: January 11, 2022
    Assignee: F. Holzer GmbH
    Inventors: Hyek Hee Lee, Ute Steinfeld, Markus Mahler, Frank Holzer
  • Publication number: 20210346900
    Abstract: The invention relates to a pump head (I) with a specially designed flexible valve (20) which securely connects the pump head. The valve ensures the pump head is securely closed. The invention also relates to a metering device which can be designed, for example as a squeeze bottle, as a non-airless system or as an airless-system. Said metering device comprises the claimed pump head.
    Type: Application
    Filed: September 20, 2019
    Publication date: November 11, 2021
    Inventors: Hyeck-Hee Lee, Frank Holzer, Ute Steinfeld, Markus Mahler
  • Patent number: 11110472
    Abstract: The present invention relates to a pump head that enables a metered dispensing of fluids. The present invention also relates to a metering apparatus that can, for example, be configured as a squeeze bottle, wherein the metering apparatus comprises a pump head in accordance with the invention.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: September 7, 2021
    Assignee: F. Holzer GmbH
    Inventors: Hyek Hee Lee, Ute Steinfeld, Markus Mahler, Frank Holzer
  • Publication number: 20210197998
    Abstract: The present invention relates to a dispensing head (1) for a dispensing device, and to a dispensing device (100) for the metered dispensing of liquid preparations, which dispensing device is provided with the dispensing head. The dispensing head comprises a special valve (6), which comprises at least one sealing lip (7a, 7b), by means of which a passage channel (3) for dispensing the liquid preparation, which passage channel is formed in the dispensing head, can be closed. The present invention is characterized by the simplicity of the dispensing head (1) and the economic advantages in the manufacturing which are linked to this simplicity.
    Type: Application
    Filed: April 1, 2019
    Publication date: July 1, 2021
    Applicant: F. HOLZER GMBH
    Inventors: Hyeck-Hee LEE, Ute STEINFELD, Markus MAHLER, Frank HOLZER
  • Patent number: 10865779
    Abstract: The present invention relates to a metering pump for a metering device, the metering pump being connectable to a storage container. The metering pump thereby comprises a non-return valve which has sealing elements on the base-side, which sealing elements enable internal sealing of the metering pump. In addition, the present invention relates to a metering device in which the metering pump according to the invention is connected to a storage container.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: December 15, 2020
    Assignee: F. Holzer GmbH
    Inventors: Hyeck-Hee Lee, Ute Steinfeld, Markus Mahler, Frank Holzer
  • Patent number: 10384221
    Abstract: The present invention relates to a pump head for a metering device for a metered dispensing of a fluid. The pump head can thereby be fitted on a storage container, for example a bottle, which is designed for storing the fluid to be dispensed. Pump head and storage vessel together thereby form the metering device according to the invention. The pump head is distinguished by including a passage for air, by means of which air from outside can be transferred into the storage vessel during the pumping process for pressure compensation. The present invention relates in addition to purposes of use for the pump head and the metering device.
    Type: Grant
    Filed: October 7, 2015
    Date of Patent: August 20, 2019
    Assignee: F. Holzer GmbH
    Inventors: Hyek Hee Lee, Ute Steinfeld, Markus Mahler, Frank Holzer
  • Publication number: 20190224705
    Abstract: The present invention relates to a pump head that enables a metered dispensing of fluids. The present invention also relates to a metering apparatus that can, for example, be configured as a squeeze bottle, wherein the metering apparatus comprises a pump head in accordance with the invention.
    Type: Application
    Filed: June 1, 2017
    Publication date: July 25, 2019
    Applicant: F. Holzer GmbH
    Inventors: Hyek Hee Lee, Ute Steinfeld, Markus Mahler, Frank Holzer
  • Publication number: 20190212179
    Abstract: The present invention relates to a pump head with a specially configured elastic valve which enables secure closure of the pump head. It is ensured by the valve that complete emptying and, at the same time, secure closing of the pump head is ensured so that no residues of fluid to be metered remain in the storage state of the pump head. In addition, the present invention relates to a metering device which can be configured for example as squeeze bottle, as non-airless system or as airless system, the metering device comprising a pump head according to the invention.
    Type: Application
    Filed: June 1, 2017
    Publication date: July 11, 2019
    Applicant: F.Holzer GmbH
    Inventors: Hyek Hee Lee, Ute Steinfeld, Markus Mahler, Frank Holzer
  • Publication number: 20190101108
    Abstract: The present invention relates to a metering pump for a metering device, the metering pump being connectable to a storage container. The metering pump thereby comprises a non-return valve which has sealing elements on the base-side, which sealing elements enable internal sealing of the metering pump. In addition, the present invention relates to a metering device in which the metering pump according to the invention is connected to a storage container.
    Type: Application
    Filed: March 21, 2017
    Publication date: April 4, 2019
    Inventors: Hyeck-Hee Lee, Ute Steinfeld, Markus Mahler, Frank Holzer
  • Publication number: 20190099441
    Abstract: The present invention relates to an ophthalmological composition with high viscosity. The composition according to the invention comprises or thereby consists of hyaluronic acid or a hyaluronic acid derivative, such as for example an ophthalmologically acceptable salt of hyaluronic acid and also ectoin or an ophthalmologically acceptable ectoin derivative. The composition is further characterised in that it comprises no further pharmaceutically active ingredient.
    Type: Application
    Filed: March 7, 2017
    Publication date: April 4, 2019
    Inventors: Markus Mahler, Isabella Warda, Ute Steinfeld, Frank Holzer
  • Publication number: 20170291183
    Abstract: The present invention relates to a pump head for a metering device for a metered dispensing of a fluid. The pump head can thereby be fitted on a storage container, for example a bottle, which is designed for storing the fluid to be dispensed. Pump head and storage vessel together thereby form the metering device according to the invention. The pump head is distinguished by including a passage for air, by means of which air from outside can be transferred into the storage vessel during the pumping process for pressure compensation. The present invention relates in addition to purposes of use for the pump head and the metering device.
    Type: Application
    Filed: October 7, 2015
    Publication date: October 12, 2017
    Inventors: Hyeck-Hee Lee, Ute Steinfeld, Markus Mahler, Frank Holzer
  • Patent number: 9415925
    Abstract: The invention relates to a metering device for metered dispensing of a fluid, in which a storage container is connected to a metering head, a spindle being guided in the metering head and having a through-channel for the fluid to be transported.
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: August 16, 2016
    Assignee: F. HOLZER GMBH
    Inventors: Hyeck Hee Lee, Frank Holzer, Ute Steinfeld, Markus Mahler
  • Publication number: 20150139973
    Abstract: The present invention relates to an ophthalmological vehicle system for the permeation and/or for the active substance transport of ophthalmological active substances through the cornea and/or the sclera of the eye of mammals. This vehicle system assists the transport of the active substances through the cornea and/or the sclerotic tissue of the eye. The vehicle system is suitable for the prophylaxis and/or treatment of diseases of the front and/or back portion of the eye. Likewise, the present invention relates to an ophthalmological kit, comprising a special ophthalmological composition and also, as separate formulation, an ophthalmological active substance.
    Type: Application
    Filed: May 14, 2013
    Publication date: May 21, 2015
    Inventors: Ute Steinfeld, Frank Holzer, Hyeck Hee Lee, Markus Mahler
  • Publication number: 20140301875
    Abstract: The invention relates to a metering pump for a metering device for metered dispensing of a liquid, which can be connected to a storage container, comprising a cylindrical pump body and an actuation body.
    Type: Application
    Filed: October 20, 2011
    Publication date: October 9, 2014
    Applicant: Ursapharm Arzneimittel GmbH
    Inventors: Hyeck-Hee Lee, Ute Steinfeld, Frank Holzer, Markus Mahler
  • Publication number: 20140287012
    Abstract: The present invention relates to an antibacterially-acting moulded article which is formed from a moulding compound which comprises at least one sort of a particular antibacterial material. The invention is distinguished by the moulded article having an essentially cylindrical, cuboid, spherical or ellipsoid basic body, the basic body having special dimensions which depend upon the average particle diameter of the particular antibacterial material which is used.
    Type: Application
    Filed: May 11, 2012
    Publication date: September 25, 2014
    Applicant: F. HOLZER GMBH
    Inventors: Hyeck-Hee Lee, Frank Holzer, Ute Steinfeld, Markus Mahler
  • Patent number: 8648057
    Abstract: The invention relates to a pharmaceutical composition free from dexpanthenol, calcium ions and phosphate, comprising at least one calcium chelating agent and at least one opthalmologically compatible viscosity regulator and optionally one or more pharmaceutical excipients. The invention further relates to the use of a calcium chelating agent and an opthalmologically compatible viscosity regulator for the production of a phosphate-free pharmaceutical composition for the treatment and/or prevention of epithelial defects.
    Type: Grant
    Filed: November 17, 2006
    Date of Patent: February 11, 2014
    Assignee: Ursapharm Arzneimittel GmbH & Co. KG
    Inventors: Frank Holzer, Dorothea Gross
  • Publication number: 20120122976
    Abstract: The invention relates to a phosphate-free pharmaceutical composition which comprises at least one FP prostanoid receptor agonist and/or at least one prostamide receptor agonist and also citrate salts and/or citric acid.
    Type: Application
    Filed: May 14, 2010
    Publication date: May 17, 2012
    Applicant: URSAPHARM ARZNEIMITTEL GMBH
    Inventor: Frank Holzer