Patents by Inventor Frank Hon

Frank Hon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aza penem compounds
    Patent number: 4431658
    Abstract: Described is a novel process for the preparation of penems and carbapenems useful as antibacterial agents which comprises the reaction of an appropriate 4-substituted-azetidine-2-one with an acid halide in the presence of a tertiary amine and an alkaline earth metal carbonate, followed by reaction of the thereby formed 1-imido-4-substituted-azetidine-2-one with a trialkyl phosphite.Also described are novel penems useful as antibacterials which are prepared by the described process.This is a division; of application Ser. No. 230,774, filed Feb. 2, 1981 now U.S. Pat. No. 4,347,183.
    Type: Grant
    Filed: June 11, 1982
    Date of Patent: February 14, 1984
    Assignee: Schering Corporation
    Inventors: Adriano Afonso, Frank Hon
  • Process for the synthesis of penems and carbapenems
    Patent number: 4347183
    Abstract: Described is a novel process for the preparation of penems and carbapenems useful as antibacterial agents which comprises the reaction of an appropriate 4-substituted-azetidine-2-one with an acid halide in the presence of a tertiary amine and an alkaline earth metal carbonate, followed by reaction of the thereby formed 1-imido-4-substituted-azetidine-2-one with a trialkyl phosphite.Also described are novel penems useful as antibacterials which are prepared by the described process.
    Type: Grant
    Filed: February 2, 1981
    Date of Patent: August 31, 1982
    Assignee: Schering Corporation
    Inventors: Adriano Afonso, Frank Hon
  • AZA penem compounds
    Patent number: RE32465
    Abstract: Described is a novel process for the preparation of penems and carbapenems useful as antibacterial agents which comprises the reaction of an appropriate 4-substituted-azetidine-2-one with an acid halide in the presence of a tertiary amine and an alkaline earth metal carbonate, followed by reaction of the thereby formed 1-imido-4-substituted-azetidine-2-one with a trialkyl phosphite.Also described are novel penems useful as antibacterials which are prepared by the described process.
    Type: Grant
    Filed: May 29, 1985
    Date of Patent: July 28, 1987
    Assignee: Schering Corporation
    Inventors: Adriano Afonso, Frank Hon