Patents by Inventor Frank Hubner

Frank Hubner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of unsaturated 4,5-allene ketones, 3,5-diene ketones and the corresponding saturated ketones
    Patent number: 6380437
    Abstract: Process for the preparation of unsaturated 4,5-allene ketones by reaction of tertiary propargyl alcohols with alkenyl alkyl ethers or ketals in the presence of aliphatic sulfonic acids or sulfonic acid salts.
    Type: Grant
    Filed: October 11, 2000
    Date of Patent: April 30, 2002
    Assignee: Degussa AG
    Inventors: Nongyuan Shi, Frank Hübner, Bernd Drapal, Rainer Peter, Steffen Krill, Klaus Huthmacher, Christoph Weckenbecker
  • Method for the production of trimethylhydroquinone
    Patent number: 6063968
    Abstract: The invention relates to an improved method for the production of 2,3,5-trimethylhydroquinone by rearranging 4-oxo-isophorone (keto-isophorone, 3,5,5-trimethylcyclohex-2-en[e]-1,4-dione) to a trimethylhydroquinone diester and by its subsequent saponification.
    Type: Grant
    Filed: May 14, 1997
    Date of Patent: May 16, 2000
    Assignee: Degussa Aktiengesellschaft
    Inventors: Frank Hubner, Steffen Krill, Bernd Drapal, Hermann Schmitt, Klaus Huthmacher, Herbert Tanner
  • Process for the production of .alpha.-tocopherol esters
    Patent number: 6048988
    Abstract: A process for the production of .alpha.-tocopherol esters, derivatives or homologs thereof of the general formula ##STR1## in which the mono- or diester of a hydroquinone is reacted with an allyl alcohol derivative or an allyl alcohol in the presence of zinc halides and proton-liberating acids at a temperature of 25.degree. to 100.degree. C.
    Type: Grant
    Filed: December 21, 1998
    Date of Patent: April 11, 2000
    Assignee: Degussa-Huls AG
    Inventors: Steffen Krill, Frank Hubner, Rainer Hahn, Horst Weigel, Klaus Huthmacher
  • Production and use of salts of 6,8-bis (amidiniumthio)-octanoic acid
    Patent number: 6013815
    Abstract: The invention relates to the production and purification of salts of 6,8-bis (amidiniumthio)octanoic acid, its enantiomers (+)-6,8-bis(amidiniumthio)octanoic acid and (-)-6,8-bis (amidiniumthio)octanoic acid and of the esters of these compounds as well as to their use to produce dihydrolipoic acid and .alpha.-lipoic acid.
    Type: Grant
    Filed: March 18, 1998
    Date of Patent: January 11, 2000
    Assignee: ASTA Medica Aktiengesellschaft
    Inventors: Thomas Beisswenger, Rainer Gewald, Alfred Olbrich, Horst Bethge, Frank Hubner, Klaus Huthmacher, Herbert Klenk, Roland Moller, Stephan Rautenberg, Gerhard Sator
  • Method of producing 3, 5, 5-trimethylcyclohexa-3-ene-1-one(.beta.-isophorone) by the isomerization of 3, 5, 5-trimethylcyclohexa-2-ene-1-(.alpha.-isophorone)
    Patent number: 6005147
    Abstract: A method of producing 3,5,5-trimethylcyclohexa-3-ene-1-one (.beta.-isophorone) including a catalyst of an oxide or mixed oxide of at least one element of the groups IIa, VIII, Ib, IIIa and Va of the periodic system. Isomerization is carried out without the addition of an organic base. The space-time yield in the production of .beta.-isophorone by the isomerization of .alpha.-isophorone is at a level suitable for an industrial application. .beta.-isophorone is especially suitable as an intermediate product for producing ketoisophorone.
    Type: Grant
    Filed: September 26, 1997
    Date of Patent: December 21, 1999
    Assignee: Degussa Aktiengesellschaft
    Inventors: Steffen Krill, Gunes Giray, Klaus Huthmacher, Frank Hubner, Herbert Tanner
  • Method of producing dry thioctic acid
    Patent number: 5981767
    Abstract: The present invention is relative to a method of producing dry thioctic acid in which a raw material in which concentrated thioctic acid is present is treated with liquid or supercritical CO.sub.2, thus yielding thioctic acid with low residual solvent contents in a simple industrial method.
    Type: Grant
    Filed: June 23, 1998
    Date of Patent: November 9, 1999
    Assignee: Asta Medica Aktiengesellschaft
    Inventors: Herbert Tanner, Karlheinz Drauz, Gerhard Sator, Horst Bethge, Roland Moller, Frank Hubner, Thomas Tacke, Claus Rehren
  • Process for the production of trimethylhydroquinone diesters and of trimethylhydroquinone
    Patent number: 5969176
    Abstract: An improved process for the production of 2,3,5-trimethylhydroquinone by rearrangement of 4-oxoisophorone (ketoisophorone, 3,5,5-trimethyl-2-cyclohexen-1,4-dione) to yield a trimethylhydroquinone diester and the subsequent saponification thereof. Trimethylhydroquinone is in turn an important starting material for the production of vitamin E.
    Type: Grant
    Filed: February 12, 1999
    Date of Patent: October 19, 1999
    Assignee: Degussa-Huls AG
    Inventors: Steffen Krill, Horst Weigel, Nongyuan Shi, Hans J. Hasselbach, Klaus Huthmacher, Frank Hubner
  • Method of producing .beta.-isophorone by the isomerization of .alpha.-isophorone
    Patent number: 5907065
    Abstract: A method of producing 3,5,5-trimethylcyclohexa-3-ene-1-one (.beta.-isophorone) by isomerization of 3,5,5-trimethylcyclohexa-2-ene-1-one (.alpha.-isophorone) in a liquid phase in the presence of a homogeneous or heterogeneous catalyst in which a mixture with a relatively low concentration of .beta.-isophorone is drawn off from the reaction container and the .beta.-isophorone isolated by vacuum distillation. .beta.-isophorone is an important synthetic structural element for the production of carotinoids, vitamins and pharmaceutical products.
    Type: Grant
    Filed: September 26, 1997
    Date of Patent: May 25, 1999
    Assignee: Degussa Aktiengesellschaft
    Inventors: Steffen Krill, Gunes Giray, Frank Hubner, Rainer Hahn, Klaus Huthmacher, Herbert Tanner
  • Method of producing ketoisophorone
    Patent number: 5874632
    Abstract: An improved method of producing 3,5,5-trimethylcyclohex-2-ene-1,4-dione (KIP) by the oxidation of 3,5,5-trimethylcyclohex-3-ene-1-one (.beta.-IP) in the presence of managansalene-like catalysts and certain catalytic additives. ##STR1## KIP is an important intermediary product in the synthesis of trimethylhydroquinone, an initial substance in the synthesis of vitamin E. Furthermore, KIP is an initial compound for the synthesis of various carotinoids.
    Type: Grant
    Filed: May 15, 1997
    Date of Patent: February 23, 1999
    Assignee: Degussa Aktiengesellschaft
    Inventors: Rainer Hahn, Ulrich Gora, Klaus Huthmacher, Frank Hubner, Steffen Krill
  • Production and use of salts of 6, 8-bis (amidiniumthio) -octanoic acid
    Patent number: 5760268
    Abstract: The invention relates to the production and purification of salts of 6,8-bis(amidiniumthio) octanoic acid, its enantiomers (+)-6,8-bis(amidiniumthio)octanoic acid and (-)-6,8-bis (amidiniumthio)octanoic acid and of the esters of these compounds as well as to their use to produce dihydrolipoic acid and .alpha.-lipoic acid.
    Type: Grant
    Filed: January 21, 1997
    Date of Patent: June 2, 1998
    Assignee: Asta Medica Aktiengesellschaft
    Inventors: Thomas Beisswenger, Rainer Gewald, Alfred Olbrich, Horst Bethge, Frank Hubner, Klaus Huthmacher, Herbert Klenk, Roland Moller, Stephan Rautenberg, Gerhard Sator
  • Method of producing salcomine
    Patent number: 5618957
    Abstract: A method of producing salcomine by reacting ethylene diamine with salicylaldehyde and a cobalt salt in a liquid reaction medium containing solvent.
    Type: Grant
    Filed: September 28, 1995
    Date of Patent: April 8, 1997
    Assignee: Degussa AG
    Inventors: Frank Hubner, Ulrich Gora, Klaus Huthmacher, Karlheinz Drauz
  • RS-thioctic acid with novel morphology
    Patent number: 5455264
    Abstract: RS-thioctic acid with a novel morphology which is obtained by a recrystallization process.
    Type: Grant
    Filed: October 12, 1993
    Date of Patent: October 3, 1995
    Assignee: ASTA Medica Aktiengesellschaft
    Inventors: Thomas Beisswenger, Horst Bethge, Joachim Goede, Frank Hubner, Klaus Huthmacher, Herbert Klenk, Roland Moller