Abstract: Methods, systems, and computer instructions for virtual radiation oncology training are provided. The methods can allow for screening of many virtual patients in a clinical setting for radiation oncology training. The methods, system, and computer instructions can include receiving a medical record for a virtual patient, presenting the medical record to a trainee, receiving a treatment plan for the virtual patient from the trainee indicating an area to be treated and dose constraints, and computing one or more comparison metrics for the treatment plan.

Abstract: A three-dimensional radiological image of a living being is acquired and an anatomical feature of interest therein is identified. A three-dimensional print of the feature is created; the print has haptic characteristics that are similar to those of the anatomical feature of interest. The print is incorporated into a model upon which a medical student can simulate a surgical operation. A simulator is provided; the simulator simulates the operation of a c-arm fluoroscope. This enables the medical student to simulate surgery while operating a fluoroscope.

Abstract: Methods, systems, and computer instructions for virtual radiation oncology training are provided. The methods can allow for screening of many virtual patients in a clinical setting for radiation oncology training. The methods, system, and computer instructions can include receiving a medical record for a virtual patient, presenting the medical record to a trainee, receiving a treatment plan for the virtual patient from the trainee indicating an area to be treated and dose constraints, and computing one or more comparison metrics for the treatment plan.

Abstract: A three-dimensional radiological image of a living being is acquired and an anatomical feature of interest therein is identified. A three-dimensional print of the feature is created; the print has haptic characteristics that are similar to those of the anatomical feature of interest. The print is incorporated into a model upon which a medical student can simulate a surgical operation. A simulator is provided; the simulator simulates the operation of a c-arm fluoroscope. This enables the medical student to simulate surgery while operating a fluoroscope.

Abstract: An imaging platform system that provides integrated navigation capabilities for surgical guidance. The system can include two robotic arm systems, one robotic arm system holding an imaging source, and the other holding an imaging sensor. These robotic arm systems are able to move and provide three-dimensional tomographic scans, static radiographic images, and dynamic fluoroscopic image sequences. A third robotic arm system can be included in the imaging platform system as a surgeon guided tool-holder to accurately implement an image-guided surgical plan. The robotic systems can manipulate imaging and surgical components into and out of the operative field as needed, enhancing the choreography between a surgical team and assistive technology. A handle can be included as part of a manual positioning control subsystem. The handle can be mounted to an imaging robotic system above and/or below an operating table, and also can be mounted to a tool-holding robotic system.

Abstract: A method of formulating a patient-specific plan for a diagnostic or therapeutic procedure performed upon a patient is provided. The method includes obtaining a standard plan based upon a scan of an anatomy of a standard anatomic specimen, the scan defining a standard scan. The method also includes scanning the patient to obtain a patient-specific scan of an anatomy of the patient. Additionally, the method includes morphing the standard scan to the anatomy of the patient by mapping the standard scan to the patient-specific scan. The method further includes determining the patient-specific plan by modifying the standard plan based upon the mapping.

Abstract: An imaging platform system that provides integrated navigation capabilities for surgical guidance. The system can include two robotic arm systems, one robotic arm system holding an imaging source, and the other holding an imaging sensor. These robotic arm systems are able to move and provide three-dimensional tomographic scans, static radiographic images, and dynamic fluoroscopic image sequences. A third robotic arm system can be included in the imaging platform system as a surgeon guided tool-holder to accurately implement an image-guided surgical plan. The robotic systems can manipulate imaging and surgical components into and out of the operative field as needed, enhancing the choreography between a surgical team and assistive technology. A handle can be included as part of a manual positioning control subsystem. The handle can be mounted to an imaging robotic system above and/or below an operating table, and also can be mounted to a tool-holding robotic system.

Abstract: This invention provides computerized image guidance systems for deep brain stimulation (DBS) surgery and related methods that improve accuracy of positioning of electrodes in the brains of subjects. Image guidance systems in accordance with the present invention incorporate advanced features such as capability of displaying, in any desired plane of view, a digitized three-dimensional neuroanatomical brain map that can be form fitted to a patient's medical images, such as brain MR images, and capability of displaying on the patient's medical images both the contours of anatomic structures from a digitized brain map, and digitized electrode recording data obtained intra-operatively.

Abstract: A method of formulating a patient-specific plan for a diagnostic or therapeutic procedure performed upon a patient is provided. The method includes obtaining a standard plan based upon a scan of an anatomy of a standard anatomic specimen, the scan defining a standard scan. The method also includes scanning the patient to obtain a patient-specific scan of an anatomy of the patient. Additionally, the method includes morphing the standard scan to the anatomy of the patient by mapping the standard scan to the patient-specific scan. The method further includes determining the patient-specific plan by modifying the standard plan based upon the mapping.

Abstract: Repeat fixation for medical procedures is accomplished using a non-invasive locator, specifically a face mask. The face mask has at least three fiducial markers on it. By detecting the position of the markers, the position of features within the patient can be determined with great precision. The features can be the location of head or neck cancer or other target to which radiation or other medical procedure is to be applied. Since the face mask has been molded to uniquely fit to the patient's face, it may be removed after an initial imaging of the patient. The face mask may then be re-attached one or more times to the teeth. The face mask is molded to conform to the patient's face by using thermoplastic material.

Abstract: A method for planning an intensity modulated radiation therapy system comprising outlining a 3D target volume, providing relative radiation intensities of the 3D, a) selecting specific beam directions for the system to use and b) optimizing the system using an arcing paradigm; back-projecting the given intensities to the selected beam entry portals; sub-dividing each entry portal into discrete dose elements; applying thereto a cost function that scores the goodness of the plan by positively rewarding doses in selected regions and negatively rewarding doses in protected regions, and adjusting the weights of each of the dose elements to increase the overall score.

Abstract: A method for planning an intensity modulated radiation therapy system comprising outlining a 3D target volume, providing relative radiation intensities of the 3D, a) selecting specific beam directions for the system to use and b) optimizing the system using an arcing paradigm; back-projecting the given intensities to the selected beam entry portals; subdividing each entry portal into discrete dose elements; applying thereto a cost function that scores the goodness of the plan by positively rewarding doses in selected regions and negatively rewarding doses in protected regions, and adjusting the weights of each of the dose elements to increase the overall score.

Abstract: A computer controlled system for guiding the needle device, such as a biopsy needle, by reference to a single mode medical imaging system employing any one of computed tomography imaging (CTI) equipment, magnetic resonance imaging equipment (MRI), fluoroscopic imaging equipment, or 3D ultrasound system, or alternatively, by reference to a multi-modal imaging system, which includes any combination of the aforementioned systems. The 3D ultrasound system includes a combination of an ultrasound probe and both passive and active infrared tracking systems so that the combined system enables a real time image display of the entire region of interest without probe movement.

Abstract: Repeat fixation for medical procedures is accomplished using a non-invasive locator, specifically a bite plate. The bite plate has at least three fiducial markers on it. The fiducial markers may be LEDs, radiopaque markers for angiography or computerized tomography (CT) imaging or magnetic resonance markers for magnetic resonance (MR) imaging. By detecting the position of the markers, the position of features within the patient (such as a brain tumor or other intracranial target to which radiation is to be applied) can be determined with great precision. Since the bite plate has been molded to uniquely fit to the patient's teeth, it may be removed after an initial imaging of the patient. The bite plate may then be re-attached one or more times to the teeth. An alternate embodiment uses a head ring or head holder such as a head mask system with the LEDs thereon. The head ring is useful for single fraction treatments.

Abstract: Repeat fixation for medical procedures is accomplished using a non-invasive locator, specifically a bite plate. The bite plate has at least three fiducial markers on it. The fiducial markers may be LEDs, radiopaque markers for angiography or computerized tomography (CT) imaging or magnetic resonance markers for magnetic resonance (MR) imaging. By detecting the position of the markers, the position of features within the patient (such as a brain tumor or other intracranial target to which radiation is to be applied) can be determined with great precision. Since the bite plate has been molded to uniquely fit to the patient's teeth, it may be removed after an initial imaging of the patient. The bite plate may then be re-attached one or more times to the teeth and the location of the features will be in a known position relative to the sensed markers.

Abstract: Stereostactic radiosurgery apparatus for eliminating misalignments due to mechanical inaccuracies and sag of a linear accelerator radiation-emitting head which is swung through an arc comprises a guiding and support structure with a first bearing system for accurately rotating a collimator through a precise arc in a vertical plane with respect to a predetermined center point in the plane corresponding to a treatment location, a second gimbal bearing system for coupling the collimator to the head so that the rotating head can drive the collimator through its arc while mechanically uncoupling the head from the collimator by eliminating torques and forces on the collimator which would be exerted by mechanical inaccuracies or sag of the head, and a third bearing system for rotatably supporting a stereotactic floorstand for rotation about a vertical axis which intersects the center point.

Abstract: Stereotactic radiosurgery is facilitated by a technique for computing the doses at various points within the patient's body. In particular, the doses are computed at a relatively high density of points within a fine dose grid and at a relatively low density of points within a coarse dose grid. In that fashion, the user can quickly obtain necessary information about the radiation dose distribution before implementation of a proposed treatment plan. An advantageous technique of locating the intersection between the radiation beam and the contour or other surface of the patient is also provided. The method is especially well suited for use with a particular structure which allows one to utilize relatively narrow beam widths as a result of great mechanical accuracy.

Abstract: An apparatus and method are provided for imaging an object undergoing high energy irradiation, such as a patient being treated by radiation teletherapy, the apparatus employing an array of ion chambers in a detector, the detector being rotatable with respect to the object, the image being obtained by acquiring projection data from each of the ion chambers at a sequence of predetermined orientations, the projection data for each location being reconstructed into an image by convolution filtering or other reconstruction technique, and subsequently employed in a back-projection of all projection data, which may then be displayed on a video monitor. The detector employs a liquid fluorocarbon as the ionizing medium in the plurality of ion chambers.