Patents by Inventor Frank Jao

Frank Jao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • System for delaying drug delivery up to seven hours
    Patent number: 7736668
    Abstract: A dosage form is disclosed comprising means for delaying the delivery of drug from the dosage form following the administration of the dosage form to a patient in need of drug therapy.
    Type: Grant
    Filed: January 28, 2003
    Date of Patent: June 15, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Frank Jao, Patrick S.-L. Wong, Hoa T. Huynh, Kathy Mc Chesney, Pamela K. Wat
  • NOVEL DRUG COMPOSITIONS AND DOSAGE FORMS OF TOPIRAMATE
    Publication number: 20070243254
    Abstract: The present invention is directed to novel drug compositions and dosage forms comprising said drug compositions. The drug compositions of the present invention comprise a pharmaceutical agent and a solubilizing agent. The drug compositions of the present invention are particularly advantageous for use with low solubility and/or low dissolution rate pharmaceutical agents. The present invention is further directed to methods for manufacturing of said drug compositions and dosage forms. The present invention is further directed to methods of treatment comprising administration of said drug compositions and dosage forms.
    Type: Application
    Filed: June 28, 2007
    Publication date: October 18, 2007
    Inventors: David Edgren, Frank Jao, Rhea Kimbel, Padmaja Shivanand, Atul Ayer, Gurdish Bhatti, Andrew Lam, Shu Li, Robert Skluzacek, Winnie To, Patrick Wong, Shaoling Li, Noymi Yam, Sylvia Serofff
  • Novel drug compositions and dosage forms of topiramate
    Publication number: 20050175697
    Abstract: The present invention is directed to novel drug compositions and dosage forms comprising said drug compositions. The drug compositions of the present invention comprise a pharmaceutical agent and a solubilizing agent. The drug compositions of the present invention are particularly advantageous for use with low solubility and/or low dissolution rate pharmaceutical agents. The present invention is further directed to methods for manufacturing of said drug compositions and dosage forms. The present invention is further directed to methods of treatment comprising administration of said drug compositions and dosage forms.
    Type: Application
    Filed: December 28, 2004
    Publication date: August 11, 2005
    Inventors: David Edgren, Frank Jao, Rhea Kimbel, Shaoling Li, Noymi Yam, Sylvia Seroff, Padmaja Shivanand
  • Novel drug compositions and dosage forms
    Publication number: 20050175690
    Abstract: The present invention is directed to novel drug compositions and dosage forms comprising said drug compositions. The drug compositions of the present invention comprise a pharmaceutical agent and a solubilizing agent. The drug compositions of the present invention are particularly advantageous for use with low solubility and/or low dissolution rate pharmaceutical agents. The present invention is further directed to methods for manufacturing of said drug compositions and dosage forms. The present invention is further directed to methods of treatment comprising administration of said drug compositions and dosage forms.
    Type: Application
    Filed: December 28, 2004
    Publication date: August 11, 2005
    Inventors: David Edgren, Frank Jao, Rhea Kimbel, Shaoling Li, Noymi Yam, Sylvia Seroff, Padmaja Shivanand
  • Methods and dosage forms for increasing solubility of drug compositions for controlled delivery
    Publication number: 20050169992
    Abstract: Dosage forms and devices for enhancing controlled delivery of pharmaceutical agents by use of a drug core composition that increases the solubility of the pharmaceutical agent are described. The present invention provides a means of delivering high doses of poorly soluble drug in oral drug delivery systems that are convenient to swallow, for once-a-day administration.
    Type: Application
    Filed: December 22, 2004
    Publication date: August 4, 2005
    Inventors: Frank Jao, David Edgren, Robert Skluzacek, Noymi Yam
  • Antiepileptic dosage form and process for protecting antiepileptic drug
    Publication number: 20040191314
    Abstract: A dosage form for delivering an antiepileptic drug to a gastrointestinal tract includes a compartment containing a drug formulation layer which comprises an antiepileptic drug. The dosage form further includes a semipermeable wall surrounding the compartment. The semipermeable wall has a passageway that allows communication between the compartment and an exterior of the dosage form. An internal lamina is formed on an inner surface of the semipermeable wall. The internal lamina is substantially soluble in water. The internal lamina in a hydrated state forms a gelatinous layer that lubricates the semipermeable wall, thereby preventing crack formation in the semipermeable wall while the dosage form is dispensing the drug.
    Type: Application
    Filed: April 2, 2004
    Publication date: September 30, 2004
    Inventors: Frank Jao, Patrick S. L. Wong, Evangeline Cruz
  • System for delaying drug delivery up to seven hours
    Patent number: 6764697
    Abstract: A dosage form is disclosed comprising means for delaying the delivery of drug from the dosage form following the administration of the dosage form to a patient in need of drug therapy.
    Type: Grant
    Filed: February 13, 1998
    Date of Patent: July 20, 2004
    Assignee: ALZA Corporation
    Inventors: Frank Jao, Patrick S. -L. Wong, Hoa T. Huynh, Kathy Mc Chesney, Pamela K. Wat
  • Formulations and dosage forms for controlled delivery of topiramate
    Publication number: 20040115262
    Abstract: Dosage forms and devices for enhancing controlled delivery of lowly soluble active agents including topiramate by use of a drug core composition that increases the solubility of the pharmaceutical agent are described. The present invention provides a drug core composition for delivering high doses of lowly soluble topiramate in solid oral drug delivery systems that are convenient to swallow, for once-a-day administration. The drug core composition contains topiramate, a surfactant and a carrier in ratios for optimal solubility and delivery.
    Type: Application
    Filed: July 28, 2003
    Publication date: June 17, 2004
    Inventors: Frank Jao, David Edgren, Patrick S.L. Wong, Robert Skluzacek, Shu Li, Andrew Lam, Atul Ayer, Shaoling Li, Winnie To
  • Methods and dosage forms for increasing solubility of drug compositions for controlled delivery
    Publication number: 20040091529
    Abstract: Dosage forms and devices for enhancing controlled delivery of pharmaceutical agents by use of a drug core composition that increases the solubility of the pharmaceutical agent are described. The present invention provides a means of delivering high doses of lowly soluble drug in oral drug delivery systems that are convenient to swallow, for once-a-day administration.
    Type: Application
    Filed: June 26, 2003
    Publication date: May 13, 2004
    Inventors: David Edgren, Patrick S.L. Wong, Frank Jao, Robert Skluzacek, Shu Li, Andrew Lam, Gurdish Bhatti, Shaoling Li, Atul Ayer, Winnie To
  • System for delaying drug delivery up to seven hours
    Publication number: 20030215510
    Abstract: A dosage form is disclosed comprising means for delaying the delivery of drug from the dosage form following the administration of the dosage form to a patient in need of drug therapy.
    Type: Application
    Filed: January 28, 2003
    Publication date: November 20, 2003
    Inventors: Frank Jao, Patrick S.-L. Wong, Hoa T. Huynh, Kathy McChesney, Pamela K. Wat
  • Effective therapy for epilepsies
    Publication number: 20030056896
    Abstract: A dosage form is disclosed for delivering an antiepileptic drug, which dosage form comprises for maintaining the integrity of the dosage form and of the antiepileptic drug.
    Type: Application
    Filed: September 30, 2002
    Publication date: March 27, 2003
    Inventors: Frank Jao, Patrick S.-L. Wong, Evangeline Cruz, Eduardo C. Sy, Anthony L. Kuczynski
  • System for delaying drug delivery up to seven hours
    Patent number: 6146662
    Abstract: A dosage form is disclosed comprising means for delaying the delivery of drug from the dosage form following the administration of the dosage form to a patient in need of drug therapy.
    Type: Grant
    Filed: March 24, 1993
    Date of Patent: November 14, 2000
    Assignee: ALZA Corporation
    Inventors: Frank Jao, Patrick S.-L. Wong, Hoa T. Huynh, Kathy Mc Chesney, Pamela K. Wat
  • Dosage form comprising antiepileptic drug
    Patent number: 5955103
    Abstract: A dosage form is disclosed for delivering an antiepileptic drug, which dosage form comprises a laminated wall for maintaining the integrity of the dosage form and of the antiepileptic drug.
    Type: Grant
    Filed: June 9, 1997
    Date of Patent: September 21, 1999
    Assignee: ALZA Corporation
    Inventors: Frank Jao, Patrick S. -L. Wong, Evangeline Cruz, Eduardo C. Sy, Anthony L. Kuczynski
  • Method for treating epilepsies
    Patent number: 5906832
    Abstract: A dosage form is disclosed for delivering an antiepileptic drug, which dosage form comprises for maintaining the integrity of the dosage form and of the antiepileptic drug.
    Type: Grant
    Filed: May 12, 1995
    Date of Patent: May 25, 1999
    Assignee: ALZA Corporation
    Inventors: Frank Jao, Patrick S.-L. Wong, Evangeline Cruz, Eduardo C. Sy, Anthony L. Kuczynski
  • Effective therapy for epilepsies
    Patent number: 5876750
    Abstract: A dosage form is disclosed for delivering an antiepileptic drug, which dosage form comprises a laminated wall for maintaining the integrity of the dosage form and of the antiepileptic drug.
    Type: Grant
    Filed: June 9, 1997
    Date of Patent: March 2, 1999
    Assignee: ALZA Corporation
    Inventors: Frank Jao, Patrick S.-L. Wong, Evangeline Cruz, Eduardo C. Sy, Anthony L. Kuczynski
  • Effective therapy for epilepsies
    Patent number: 5863558
    Abstract: A dosage form is disclosed for delivering an antiepileptic drug, which dosage form comprises a laminated wall for maintaining the integrity of the dosage form and of the antiepileptic drug.
    Type: Grant
    Filed: October 21, 1997
    Date of Patent: January 26, 1999
    Assignee: Alza Corporation
    Inventors: Frank Jao, Patrick S.-L. Wong, Evangeline Cruz, Eduardo C. Sy, Anthony L. Kuczynski
  • Effective therapy for epilepsies
    Patent number: 5660861
    Abstract: A dosage form is disclosed for delivering an antiepileptic drug, which dosage form comprises for maintaining the integrity of the dosage form and of the antiepileptic drug.
    Type: Grant
    Filed: May 12, 1995
    Date of Patent: August 26, 1997
    Assignee: ALZA Corporation
    Inventors: Frank Jao, Patrick S.-L. Wong, Evangeline Cruz, Eduardo C. Sy, Anthony L. Kuczynski
  • Therapy delayed
    Patent number: 5252338
    Abstract: A dosage form is disclosed comprising means for delaying the delivery of drug from the dosage form following the administration of the dosage form to a patient in need of drug therapy.
    Type: Grant
    Filed: November 2, 1992
    Date of Patent: October 12, 1993
    Assignee: Alza Corporation
    Inventors: Frank Jao, Patrick S. L. Wong, Hoa T. Huynh, Kathy McChesney, Pamela K. Wat
  • Therapy delayed
    Patent number: 5190765
    Abstract: A dosage form is disclosed comprising means for delaying the delivery of drug from the dosage form following the administration of the dosage form to a patient in need of drug therapy.
    Type: Grant
    Filed: November 26, 1991
    Date of Patent: March 2, 1993
    Assignee: ALZA Corporation
    Inventors: Frank Jao, Patrick S. L. Wong, Hoa T. Huynh, Kathy McChesney, Pamela K. Wat
  • Verapmil therapy
    Patent number: 5160744
    Abstract: A dosage form is disclosed comprising means for delaying the delivery of drug from the dosage form following the administration of the dosage form to a patient in need of drug therapy.
    Type: Grant
    Filed: June 27, 1991
    Date of Patent: November 3, 1992
    Assignee: Alza Corporation
    Inventors: Frank Jao, Patrick S. Wong, Hoa T. Huynh, Kathy McChesney, Pamela K. Wat