Patents by Inventor Frank LÖSCHER

Frank LÖSCHER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Opthalmic compositions comprising F6H8
    Patent number: 11896559
    Abstract: The present disclosure provides methods of treatment using ophthalmic compositions comprising semifluorinated alkanes for keratoconjunctivitis sicca and/or Meibomian gland dysfunction, which methods provide for the enrichment of an ophthalmic tissue in the semifluorinated alkane, and optionally methods of delayed release of the semifluorinated alkane from the enriched ophthalmic tissue to the surface of the cornea and/or conjunctiva, and/or to the Meibomian gland.
    Type: Grant
    Filed: October 3, 2018
    Date of Patent: February 13, 2024
    Assignee: NOVALIQ GMBH
    Inventors: Bernhard Günther, Frank Löscher, Hartmut Voss, Sonja Krösser, Kirsten Eickhoff, Daniela Willen, Markus Beier, Thomas Schlüter
  • OPHTHALMIC COMPOSITIONS COMPRISING LATANOPROST FOR USE IN THE TREATMENT OF OCULAR DISEASES
    Publication number: 20230398065
    Abstract: The invention provides a pharmaceutical composition for use in the prevention or therapy of glaucoma, increased intraocular pressure, ocular hypertension and/or a symptom associated therewith, wherein—the composition comprises latanoprost and a liquid vehicle comprising a semifluorinated alkane; and—the composition is administered to the eye of a subject; and—the amount of latanoprost administered in a single dose per eye is in the range of from about 0.5 to 1.4 ?g.
    Type: Application
    Filed: June 12, 2023
    Publication date: December 14, 2023
    Inventors: Bernhard GÜNTHER, Frank LÖSCHER, Kirsten EICKHOFF
  • Ophthalmic compositions comprising latanoprost for use in the treatment of ocular diseases
    Patent number: 11723861
    Abstract: The invention provides a pharmaceutical composition for use in the prevention or therapy of glaucoma, increased intraocular pressure, ocular hypertension and/or a symptom associated therewith, wherein—the composition comprises latanoprost and a liquid vehicle comprising a semifluorinated alkane; and—the composition is administered to the eye of a subject; and—the amount of latanoprost administered in a single dose per eye is in the range of from about 0.5 to 1.4 ?g.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: August 15, 2023
    Assignee: NOVALIQ GMBH
    Inventors: Bernhard Günther, Frank Löscher, Kirsten Eickhoff
  • Pharmaceutical compositions for use in the therapy of blepharitis
    Patent number: 11684589
    Abstract: The present invention provides a pharmaceutical composition comprising 1-perfluorohexyl-octane (F6H8) for use in the therapy, treatment, prevention or amelioration of anterior or posterior blepharitis, preferably posterior blepharitis or symptoms associated therewith. Furthermore, the present invention provides a pharmaceutical kit for the therapy of anterior or posterior blepharitis or symptoms associated therewith.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: June 27, 2023
    Assignee: NOVALIQ GMBH
    Inventors: Bernhard Günther, Frank Löscher, Sonja Krösser
  • OPHTHALMIC COMPOSITION FOR THE TREATMENT OF UVEITIS
    Publication number: 20230181679
    Abstract: The invention provides pharmaceutical compositions comprising cyclosporine dissolved in a semifluorinated alkane for use in the treatment of uveitis.
    Type: Application
    Filed: September 5, 2020
    Publication date: June 15, 2023
    Inventors: Jörg HAISSER, Frank LÖSCHER, Chiara Silvana LEO, Markus BEIER
  • ANTIPARASITIC COMPOSITION
    Publication number: 20230066008
    Abstract: The present invention relates to an antiparasitic composition comprising an antiparasitic agent and a semifluorinated alkane.
    Type: Application
    Filed: February 6, 2021
    Publication date: March 2, 2023
    Applicant: DERMALIQ THERAPEUTICS, INC.
    Inventors: Frank LÖSCHER, Verena JUNG, Mikhail BARKOVSKIY, Bernhard HAUPTMEIER, Chiara Silvana LEO
  • Pharmaceutical compositions comprising nebivolol
    Patent number: 11576893
    Abstract: The present invention relates to pharmaceutical compositions comprising the selective beta 1 (B1)-receptor blocker nebivolol and/or a pharmaceutically acceptable salt thereof and a liquid vehicle comprising a semifluorinated alkane. The pharmaceutical composition of the present invention is useful for topical administration, for example ophthalmic topical administration and for use in the treatment of glaucoma, increased intraocular pressure, ocular hypertension and/or a symptom associated therewith.
    Type: Grant
    Filed: March 1, 2019
    Date of Patent: February 14, 2023
    Assignee: NOVALIQ GMBH
    Inventors: Frank Löscher, Kirsten Eickhoff, Diana Strehl
  • OPHTHALMIC COMPOSITION FOR TREATMENT OF DRY EYE DISEASE
    Publication number: 20230043641
    Abstract: The invention provides pharmaceutical compositions comprising about 0.05 to 0.1% (w/v) cyclosporine dissolved in 1-perfluorobutyl-pentane for use in the topical treatment of dry eye disease and provides for dosing and treatment methods thereof. The invention further provides kits comprising such compositions.
    Type: Application
    Filed: September 19, 2022
    Publication date: February 9, 2023
    Applicant: NOVALIQ GMBH
    Inventors: Markus BEIER, Jörg HAISSER, Alice MEIDES, Sonja KRÖSSER, Hartmut VOSS, Frank LÖSCHER, Bernhard GÜNTHER
  • Topical sunscreen formulation
    Patent number: 11510855
    Abstract: The present disclosure relates to topical sunscreen formulations comprising a semifluorinated alkane and a metal oxide selected from titanium dioxide, zinc oxide or mixtures thereof.
    Type: Grant
    Filed: September 20, 2019
    Date of Patent: November 29, 2022
    Assignee: DERMALIQ THERAPEUTICS, INC.
    Inventors: Frank Löscher, Ralf Grillenberger, Chiara Silvana Leo, Markus Beier
  • SEMIFLUORINATED COMPOUNDS AND THEIR COMPOSITIONS
    Publication number: 20220370377
    Abstract: The present invention is directed to compositions comprising semifluorinated compounds and their use as medicaments for topical administration to the eye.
    Type: Application
    Filed: June 6, 2022
    Publication date: November 24, 2022
    Inventors: Dieter SCHERER, Ralf GRILLENBERGER, Frank LÖSCHER, Hartmut VOSS
  • TOPICAL COMPOSITION COMPRISING A PROSTAGLANDIN ANALOGUE
    Publication number: 20220362382
    Abstract: The present invention relates to a topical composition useful for the treatment of hair disorders such as androgenetic alopecia, hirsutism, alopecia of the eyebrows and eyelashes, and hypotrichosis.
    Type: Application
    Filed: August 6, 2020
    Publication date: November 17, 2022
    Inventors: Frank LÖSCHER, Bernhard HAUPTMEIER
  • OPHTHALMIC COMPOSITIONS COMPRISING CICLOSPORIN
    Publication number: 20220354926
    Abstract: The present invention relates to compositions in the form of a clear solution comprising ciclosporin with low residual water content and 1-perfluorobutyl-pentane. The compositions may be used for topical administration to the eye.
    Type: Application
    Filed: July 25, 2022
    Publication date: November 10, 2022
    Applicant: NOVALIQ GMBH
    Inventors: Frank LÖSCHER, Ralf GRILLENBERGER, Johan ENGBLOM
  • Ophthalmic compositions comprising ciclosporin
    Patent number: 11400132
    Abstract: The present invention relates to compositions in the form of a clear solution comprising ciclosporin with low residual water content and 1-perfluorobutyl-pentane. The compositions may be used for topical administration to the eye.
    Type: Grant
    Filed: October 13, 2020
    Date of Patent: August 2, 2022
    Assignee: NOVALIQ GMBH
    Inventors: Frank Löscher, Ralf Grillenberger, Johan Engblom
  • OPHTHALMIC COMPOSITION FOR THE TREATMENT OF OCULAR ALLERGY
    Publication number: 20220226426
    Abstract: The invention provides ophthalmic composition comprising cyclosporine and a semifluorinated alkane for use in the treatment of ocular allergy and any symptoms associated thereto.
    Type: Application
    Filed: May 23, 2020
    Publication date: July 21, 2022
    Inventors: Frank LÖSCHER, Markus BEIER, Chiara Silvana LEO
  • Semifluorinated compounds and their compositions
    Patent number: 11357738
    Abstract: The present invention is directed to compositions comprising semifluorinated compounds and their use as medicaments for topical administration to the eye.
    Type: Grant
    Filed: May 14, 2020
    Date of Patent: June 14, 2022
    Assignee: NOVALIQ GMBH
    Inventors: Dieter Scherer, Ralf Grillenberger, Frank Löscher, Hartmut Voss
  • IODINE COMPOSITIONS
    Publication number: 20220152096
    Abstract: The present invention relates to compositions comprising molecular iodine and a vehicle comprising a semifluorinated alkane. The compositions of the invention may be used to treat or prevent diseases or conditions caused by, or associated with microorganisms.
    Type: Application
    Filed: February 4, 2022
    Publication date: May 19, 2022
    Inventors: Frank LÖSCHER, Ralf GRILLENBERGER
  • LIPID BARRIER REPAIR
    Publication number: 20220079980
    Abstract: The present disclosure is in the field of ointments which can be useful for the treatment of diseases or conditions associated with lipid barrier damage of the skin. The ointment comprises a semifluorinated alkane and a solid thickening agent, e.g., a wax, a triglyceride, cetyl alcohol, cetyl palmitate, or tetradecanol.
    Type: Application
    Filed: September 20, 2019
    Publication date: March 17, 2022
    Inventors: Frank LÖSCHER, Ralf GRILLENBERGER, Chiara Silvana LEO, Markus BEIER
  • Iodine compositions
    Patent number: 11273174
    Abstract: The present invention relates to compositions comprising molecular iodine and a vehicle comprising a semifluorinated alkane. The compositions of the invention may be used to treat or prevent diseases or conditions caused by, or associated with microorganisms.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: March 15, 2022
    Assignee: NOVALIQ GMBH
    Inventors: Frank Löscher, Ralf Grillenberger
  • SEMIFLUORINATED ALKANE COMPOSITIONS COMPRISING OMEGA-3 FATTY ACID ETHYL ESTERS
    Publication number: 20220031844
    Abstract: The invention provides compositions comprising omega-3 fatty acid ethyl esters, specifically compositions that are based on semifluorinated alkanes. The compositions of the present invention may be topical ophthalmic compositions useful in the treatment of ocular diseases or conditions. The invention further provides kits comprising such compositions.
    Type: Application
    Filed: November 25, 2019
    Publication date: February 3, 2022
    Inventors: Jörg Martin MAUDEN, Anja STICHER, Emanuele FRANZINI, Frank LÖSCHER, Michael COORS
  • Semifluorinated compounds
    Patent number: 11154513
    Abstract: The present invention is directed to certain semifluorinated compounds and to compositions comprising such compounds. The invention further provides the use of the compounds and of the compositions as medicaments for topical administration to the eye.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: October 26, 2021
    Assignee: NOVALIQ GMBH
    Inventors: Dieter Scherer, Ralf Grillenberger, Frank Löscher, Hartmut Voss