Abstract: A spine stabilization device having an interbody spacer shaped to be inserted between a vertebral body of an upper vertebra and a vertebral body of a lower vertebra. The device further includes a fixation device to be inserted after placement of the interbody spacer, the fixation device having a support portion securing the interbody spacer against escaping from between the vertebral bodies into a ventral direction. The support portion rests against a portion of an anterior surface of the interbody spacer, and includes an anchor. The anchor has an anchoring material portion that is inserted, in a liquid state, into cancellous bone tissue of at least one of the vertebral bodies of the upper and lower vertebra, to thereby infiltrate the cancellous bone tissue, and to harden thereafter so as to fix the support portion to the vertebral body.

Abstract: In one form, a system for use in percutaneous surgical procedures includes a cannula having an elongate body extending along a longitudinal axis between a proximal end and a distal end and including a working channel dynamically expandable from a first, unexpanded configuration. The system also includes a device that is positionable in and engageable with the working channel to expand the working channel from the first configuration as the device is moved through the working channel. In response to disengagement of the device with the working channel, the working channel returns to the first, unexpanded configuration. In one aspect of this form, the device includes an interbody spinal implant that is deliverable to a surgical site through the working channel of the cannula. In another form, a method for performing a percutaneous surgical procedure is provided. However, different forms and applications are envisioned.

Abstract: A spine stabilization device is provided, the spine stabilization device including an interbody spacer shaped to be inserted between a vertebral body of an upper vertebra and a vertebral body of a lower vertebra, and including a top surface oriented towards the lower endplate of the vertebral body of the upper vertebra and a bottom surface oriented towards the upper endplate of the vertebral body of the lower vertebra; and a fixation device to be inserted after placement of the interbody spacer, the fixation device including a support portion securing the interbody spacer against escaping from between the vertebral bodies of the upper and lower vertebra into a ventral direction, the support portion shaped to rest against a portion of an anterior surface of the interbody spacer, and further including an anchor, the anchor including an anchoring material portion that is configured to be inserted, in a liquid state, into cancellous bone tissue of at least one of the vertebral body of the upper vertebra and of th

Abstract: In one form, a system for use in percutaneous surgical procedures includes a cannula having an elongate body extending along a longitudinal axis between a proximal end and a distal end and including a working channel dynamically expandable from a first, unexpanded configuration. The system also includes a device that is positionable in and engageable with the working channel to expand the working channel from the first configuration as the device is moved through the working channel. In response to disengagement of the device with the working channel, the working channel returns to the first, unexpanded configuration. In one aspect of this form, the device includes an interbody spinal implant that is deliverable to a surgical site through the working channel of the cannula. In another form, a method for performing a percutaneous surgical procedure is provided. However, different forms and applications are envisioned.

Abstract: An encapsulated three-dimensional (3-D) bone matrix composition for inducing bone growth includes a 3-D bone matrix, an oxygen carrier incorporated into the 3-D bone matrix, and an encapsulation material which encapsulates the 3-D bone matrix incorporated with the oxygen carrier. Methods are disclosed for preparing an encapsulated 3-D bone matrix that can be maintained in packaging.

Abstract: An improved composition for inducing bone growth is provided that is a mixture of DBM and a perfluorocarbon oxygen carrier. Injection/implantation of a composition of DBM and a perfluorocarbon results in enhancement of bone formation.

Abstract: An improved composition for inducing bone growth is provided that is a mixture of DBM and a perfluorocarbon oxygen carrier. Injection/implantation of a composition of DBM and a perfluorocarbon results in enhancement of bone formation.

Abstract: An improved composition for inducing bone growth is provided that is a mixture of DBM and a perfluorocarbon oxygen carrier. Injection/implantation of a composition of DBM and a perfluorocarbon results in enhancement of bone formation.

Abstract: A cannula assembly and related methods of use. The cannula assembly includes a cannula and a stylet. The cannula has an outer surface that is non-circular. Rotation of the cannula about its longitudinal axis changes the orientation of the cannula's larger outer dimension so that the cannula may be used as a distraction tool. Rotation is effected by rotating a stylet handle, which rotates the associated stylet shaft, which in turn rotates the cannula. Related methods include rotating a handle of the stylet, while the shaft of the stylet is disposed in the bore of the cannula, about the first longitudinal axis so as to rotate the cannula about the longitudinal axis to distract vertebral bodies.

Abstract: In one form, a system for use in percutaneous surgical procedures includes a cannula having an elongate body extending along a longitudinal axis between a proximal end and a distal end and including a working channel dynamically expandable from a first, unexpanded configuration. The system also includes a device that is positionable in and engageable with the working channel to expand the working channel from the first configuration as the device is moved through the working channel. In response to disengagement of the device with the working channel, the working channel returns to the first, unexpanded configuration. In one aspect of this form, the device includes an interbody spinal implant that is deliverable to a surgical site through the working channel of the cannula. In another form, a method for performing a percutaneous surgical procedure is provided. However, different forms and applications are envisioned.

Abstract: An improved composition for inducing bone growth is provided that is a combination of at least DBM and an oxygen carrier. Injection/implantation of a composition of DBM and an oxygen carrier (e.g. a perfluorocarbon) results in enhancement of bone formation compared to DBM alone.

Abstract: Constrained fluid delivery devices are described that deliver fluid to an anatomical region of a mammal in a controlled release manner where the device comprises an elongate body defining a lumen throughout a portion thereof, a distal end interiorly positionable adjacent the anatomical region of the mammal and a proximal end in communication with an exterior of the mammal. The device also includes a delivery member and one or more withdrawal members. Also provided herein are methods and kits incorporating the fluid delivery device.

Abstract: A spine stabilization device is provided, the spine stabilization device including an interbody spacer shaped to be inserted between a vertebral body of an upper vertebra and a vertebral body of a lower vertebra, and including a top surface oriented towards the lower endplate of the vertebral body of the upper vertebra and a bottom surface oriented towards the upper endplate of the vertebral body of the lower vertebra; and a fixation device to be inserted after placement of the interbody spacer, the fixation device including a support portion securing the interbody spacer against escaping from between the vertebral bodies of the upper and lower vertebra into a ventral direction, the support portion shaped to rest against a portion of an anterior surface of the interbody spacer, and further including an anchor, the anchor including an anchoring material portion that is configured to be inserted, in a liquid state, into cancellous bone tissue of at least one of the vertebral body of the upper vertebra and of th

Abstract: A system and methods for performing spinal fixation, including a spinal fixation system with at least rod member having shaped ends, at least two pedicle screws capable of receiving the shaped ends of the rod member, and a system for percutaneously introducing the rod member and pedicle screws to perform spinal fixation.

Abstract: Several embodiments of cutting tips for tools for creating voids in interior body regions are provided. The cutting tips provide for rotational and translational cutting. An actuator mechanism for deploying a cutting tip converts the rotational movement of a wheel into translational movement of a plunger rod. The actuator mechanism provides positive cutting action as the cutting tip is moved from a first, non-deployed position to a second, deployed position and from the second, deployed position to the first, non-deployed position. Methods of creating a void in bone provide one or more mechanical cutting tools that may be used in combination with one or more expandable void-creating structures to form a void of a desired size and configuration.