Patents by Inventor Frank Mercer

Frank Mercer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230314369
    Abstract: Provided herein is an electrophoresis separation medium comprising: (a) a non-crosslinked or sparsely cross-linked polymer or copolymer; (b) one or more denaturant compounds, in an amount sufficient to inhibit re-naturation of single stranded polynucleotides; (c) an aqueous solvent; (d) optionally, a wall-coating material suited to inhibition of electroosmotic flow; and (e) optionally, an organic water miscible solvent such as DMSO or acetonitrile, wherein the electrophoresis separation medium exhibits functional stability for at least seven days at 23° C. Also provided herein are sieving compositions, including polymer-based sieving compositions, for molecular sieving as well as related kits, devices and methods of use. Such compositions can be useful for separation of biomolecules such as nucleic acids, proteins, glycoproteins and glycans.
    Type: Application
    Filed: February 10, 2023
    Publication date: October 5, 2023
    Inventors: Jen-Kuei LIU, Bharti SOLANKI, Hans Michael WENZ, Frank MERCER, Cevat AKIN, Achim KARGER, Annelise BARRON, Scott MACK
  • Patent number: 11619608
    Abstract: Provided herein is an electrophoresis separation medium comprising: (a) a non-crosslinked or sparsely cross-linked polymer or copolymer; (b) one or more denaturant compounds, in an amount sufficient to inhibit re-naturation of single stranded polynucleotides; (c) an aqueous solvent; (d) optionally, a wall-coating material suited to inhibition of electroosmotic flow; and (e) optionally, an organic water miscible solvent such as DMSO or acetonitrile, wherein the electrophoresis separation medium exhibits functional stability for at least seven days at 23° C. Also provided herein are sieving compositions, including polymer-based sieving compositions, for molecular sieving as well as related kits, devices and methods of use. Such compositions can be useful for separation of biomolecules such as nucleic acids, proteins, glycoproteins and glycans.
    Type: Grant
    Filed: May 22, 2018
    Date of Patent: April 4, 2023
    Inventors: Jen-Kuei Liu, Bharti Solanki, Hans Michael Wenz, Frank Mercer, Cevat Akin, Achim Karger, Annelise Barron, Scott Mack
  • Publication number: 20200141901
    Abstract: Provided herein is an electrophoresis separation medium comprising: (a) a non-crosslinked or sparsely cross-linked polymer or copolymer; (b) one or more denaturant compounds, in an amount sufficient to inhibit re-naturation of single stranded polynucleotides; (c) an aqueous solvent; (d) optionally, a wall-coating material suited to inhibition of electroosmotic flow; and (e) optionally, an organic water miscible solvent such as DMSO or acetonitrile, wherein the electrophoresis separation medium exhibits functional stability for at least seven days at 23° C. Also provided herein are sieving compositions, including polymer-based sieving compositions, for molecular sieving as well as related kits, devices and methods of use. Such compositions can be useful for separation of biomolecules such as nucleic acids, proteins, glycoproteins and glycans.
    Type: Application
    Filed: May 22, 2018
    Publication date: May 7, 2020
    Inventors: Jen-Kuei LIU, Bharti SOLANKI, Hans Michael WENZ, Frank MERCER, Cevat AKIN, Achim KARGER, Annelise BARRON, Scott MACK
  • Publication number: 20140287416
    Abstract: A polyelectrolyte-coated particle, devices for using the particle, methods for using the particle for separating PCR reaction products and/or DNA sequencing reaction products, and compositions for coating the particle are provided.
    Type: Application
    Filed: February 14, 2014
    Publication date: September 25, 2014
    Inventors: Michael HARROLD, Aldrich LAU, Ben JOHNSON, Gilbert AMPARO, Frank MERCER
  • Publication number: 20060160122
    Abstract: A polyelectrolyte-coated particle, devices for using the particle, methods for using the particle for separating PCR reaction products and/or DNA sequencing reaction products, and compositions for coating the particle are provided.
    Type: Application
    Filed: February 15, 2006
    Publication date: July 20, 2006
    Applicant: Applera Corporation
    Inventors: Michael Harrold, Aldrich Lau, Ben Johnson, Gilbert Amparo, Frank Mercer
  • Patent number: 5849824
    Abstract: The invention provides for a thermoset or thermoplastic gel composition containing a polymer with anhydride groups along the polymer backbone at least at outset of the fabrication process and an extender fluid, optionally including thermally conductive fillers. The gel compositions are useful for sealing wires, vibration dampening, sporting goods, and toys.
    Type: Grant
    Filed: February 6, 1996
    Date of Patent: December 15, 1998
    Assignee: Raychem Corporation
    Inventors: Frank Mercer, Hendrik Graulus
  • Patent number: 5145936
    Abstract: A fluorinated poly(naphthyl ether) having a repeat unit of the formula ##STR1## wherein Y is (CF.sub.2).sub.m, ##STR2## m is an integer from 1 to 4, inclusive, and X is S, CO, SO.sub.2, O, P(C.sub.6 H.sub.5), or C(OH)H. Such polymers are useful as low dielectric constant, low moisture absorption insulators for multilayered integrated circuit articles, especially in their crosslinked form.
    Type: Grant
    Filed: September 6, 1991
    Date of Patent: September 8, 1992
    Assignee: Raychem Corporation
    Inventor: Frank Mercer
  • Patent number: 5108840
    Abstract: A fluorinated poly(naphthyl ether) having a repeat unit of the formula ##STR1## wherein Y is (CF.sub.2).sub.m, ##STR2## m is an integer from 1 to 4, inclusive, and X is S, CO, SO.sub.2, O, P(C.sub.6 H.sub.5), or C(OH)H. Such polymers are useful as low dielectric constant, low moisture absorption insulators for multilayered integrated circuit articles, especially in their crosslinked form.
    Type: Grant
    Filed: December 8, 1989
    Date of Patent: April 28, 1992
    Assignee: Raychem Corporation
    Inventor: Frank Mercer
  • Patent number: 5047487
    Abstract: This invention relates to novel compositions of a poly(imide) having phenylindane diamine and/or dianhydride moieties in the poly(imide) backbone and a polymeric component comprising:(a) a poly(etherimide) free of phenyl indane moieties in its backbone;(b) a poly(sulfone);(c) a poly(aryl ether ketone);(d) a poly(carbonate); or(e) a poly(arylate);and the compositions which have been cured. The compositions are useful as adhesives, coatings and matrix resins for fiber reinforced composites. The invention also relates to a multi-layered article for use in electronic devices, the article comprising a plurality of layers each comprising a cured composition of the invention with one or more intervening layers of conductive or semi-conductive material.
    Type: Grant
    Filed: April 10, 1989
    Date of Patent: September 10, 1991
    Assignee: Raychem Corporation
    Inventors: Rafael Camargo, Frank Mercer, Tai C. Cheng
  • Patent number: 4920005
    Abstract: This invention relates to novel curable compositions comprising (a) a first component comprising an aromatic polymer having a first preponderant repeat unit and (b) a second component comprising an acetylene, maleimide, or vinyl terminated poly(imide) or poly(isoimide) or precursor thereof, which second component is compatible with the first component, has 1 to 300 second preponderant repeat units which are different from the first preponderant repeat units of the first component, is substantially free of elemental sulfur and reactive divalent sulfur, and is present in an amount effective to substantially cure the composition. The compositions are useful as adhesives, coatings and matrix resins for fiber reinforced composites. They exhibit improved adhesion to various substrates, increased tensile strength and improved resistance to cracking. The invention also relates to the composition which contains a reinforcing filler. The invention also relates to the composition after it has been cured.
    Type: Grant
    Filed: May 23, 1989
    Date of Patent: April 24, 1990
    Assignee: Raychem Corporation
    Inventor: Frank Mercer
  • Patent number: 4835197
    Abstract: This invention relates to novel curable compositions comprising (a) a first component comprising an aromatic polymer having a first preponderant repeat unit and (b) a second component comprising an acetylene, maleimide, or vinyl terminated poly(imide) or poly(isoimide) or precursor thereof, which second component is compatible with the first component, has 1 to 300 second preponderant repeat units which are different from the first preponderant repeat units of the first component, is substantially free of elemental sulfur and reactive divalent sulfur, and is present in an amount effective to substantially cure the composition. The compositions are useful as adhesives, coatings and matrix resins for fiber reinforced composites. They exhibit improved adhesion to various substrates, increased tensile strength and improved resistance to cracking. The invention also relates to the composition which contains a reinforcing filler. The invention also relates to the composition after it has been cured.
    Type: Grant
    Filed: January 27, 1987
    Date of Patent: May 30, 1989
    Assignee: Raychem Corporation
    Inventor: Frank Mercer