Patents by Inventor Frank Michiels
Frank Michiels has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20160106049Abstract: Methods are provided for hybrid seed production using 3-phyletic crosses between female, maintainer and male, particularly restorer lines, wherein the trait is introduced in the female line only at the stage of basic seed production via crossing of the female line with a maintainer line containing the gene or genes encoding the trait in homozygous state.Type: ApplicationFiled: May 23, 2014Publication date: April 21, 2016Inventors: Frank Michiels, KIrk Johnson
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Patent number: 8313909Abstract: The invention provides specific transgenic rice plants, plant material and seeds, characterized in that these products harbor a specific transformation event at a specific location in the rice genome. Tools are also provided which allow rapid and unequivocal identification of the event in biological samples.Type: GrantFiled: March 1, 2011Date of Patent: November 20, 2012Assignee: Bayer Cropscience N.V.Inventors: Marc De Beuckeleer, Kirk Johnson, Frank Michiels
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Publication number: 20110165571Abstract: The invention provides specific transgenic rice plants, plant material and seeds, characterized in that these products harbor a specific transformation event at a specific location in the rice genome. Tools are also provided which allow rapid and unequivocal identification of the event in biological samples.Type: ApplicationFiled: March 1, 2011Publication date: July 7, 2011Applicant: Bayer Bioscience N.V.Inventors: Marc DE BEUCKELEER, Kirk Johnson, Frank Michiels
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Patent number: 7928295Abstract: The invention provides specific transgenic rice plants, plant material and seeds, characterized in that these products harbor a specific transformation event at a specific location in the rice genome. Tools are also provided which allow rapid and unequivocal identification of the event in biological samples.Type: GrantFiled: August 24, 2007Date of Patent: April 19, 2011Assignee: Bayer Bioscience N.V.Inventors: Marc De Beuckeleer, Kirk Johnson, Frank Michiels
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Publication number: 20080289060Abstract: The invention provides specific transgenic rice plants, plant material and seeds, characterized in that these products harbor a specific transformation event at a specific location in the rice genome. Tools are also provided which allow rapid and unequivocal identification of the event in biological samples.Type: ApplicationFiled: August 24, 2007Publication date: November 20, 2008Applicant: BAYER BIOSCIENCE N.V.Inventors: MARC DE BEUCKELEER, KIRK JOHNSON, FRANK MICHIELS
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Patent number: 6933111Abstract: This invention pertains to plants, plant material and seeds characterized by harboring a specific transformation event particularly by the presence of the bar gene under control of a CaMV 35S promoter, at a specific location in the rice genome. The rice plants of the invention combine glufosinate tolerance with optimal overall agronomic performance, genetic stability and adaptability to different genetic backgrounds.Type: GrantFiled: April 28, 2000Date of Patent: August 23, 2005Assignee: Bayer BioScience N.V.Inventors: Marc De Beuckeleer, Frank Michiels, Kirk Johnson
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Patent number: 6759575Abstract: An improved barstar gene and improved barstar protein can be used to neutralize the activity of a barnase in eukaryotic cells, particular in plant cells. The improved barstar gene can be used to produce fertility restorer plants capable of restoring the fertility to a line of male-sterile plants that contain in the nuclear genome of their cells a chimeric gene comprising a stamen-selective promoter and a DNA coding for a barnase. Restorer plants containing the barstar gene in the restorer plant's nuclear genome is also disclosed.Type: GrantFiled: October 5, 2001Date of Patent: July 6, 2004Assignee: Bayer Bioscience N.V.Inventors: Frank Michiels, Mark Williams
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Patent number: 6468747Abstract: This invention pertains to rice plants, plant material and seeds characterized by harboring a specific transformation event particularly by the presence of the bar gene under control of a CaMV 35S promoter, at a specific location in the rice genome. The rice plants of the invention combine glufosinate tolerance with optimal overall agronomic performance, genetic stability and adaptability to different genetic backgrounds.Type: GrantFiled: December 23, 1999Date of Patent: October 22, 2002Assignee: Plant Genetic System, N.V.Inventors: Marc De Beuckeleer, Frank Michiels, Kirk Johnson
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Publication number: 20020133845Abstract: An improved barstar gene and improved barstar protein can be used to neutralize the activity of a barnase in eukaryotic cells, particular in plant cells. The improved barstar gene can be used to produce fertility restorer plants capable of restoring the fertility to a line of male-sterile plants that contain in the nuclear genome of their cells a chimeric gene comprising a stamen-selective promoter and a DNA coding for a barnase. Restorer plants containing the barstar gene in the restorer plant's nuclear genome is also disclosed.Type: ApplicationFiled: October 5, 2001Publication date: September 19, 2002Applicant: Plant Genetic Systems NVInventors: Frank Michiels, Mark Williams
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Patent number: 6372960Abstract: Improved barstar DNAs, such as synthetic barstar DNAs, produce high amounts of barstar protein in eucaryotic cells, particularly in plant cells, and especially in stamen cells such as tapetum cells. Synthetic barstar DNAs have less than 40% A and T nucleotides. Other improved barstar DNAs encode improved barstar proteins which have an N-terminus which starts with Met-Xaa wherein Xaa is Alanine, Valine, Glycine, Aspartic acid or Glutamic acid. Plan cells and plants contain the improved barstar DNAs and/or express the improved barstar protein.Type: GrantFiled: August 26, 1998Date of Patent: April 16, 2002Assignee: Plant Genetic Systems, N.V.Inventors: Frank Michiels, Mark Williams
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Patent number: 6344602Abstract: A plant having in the nuclear genome of its cells foreign DNA comprising i) a male-sterility gene comprising a male-sterility DNA encoding a sterility RNA, protein or polypeptide which, when produced or overproduced in a stamen cell of the plant, significantly disturbs the metabolism, functioning and/or development of the stamen cell, and, a sterility promoter directing expression of the male-sterility DNA selectively in specific stamen cells of said plant, the male-sterility DNA being in the same transcriptional unit as, and under the control of, the sterility promoter, and ii) a coregulating gene comprising a coregulating DNA encoding a coregulating RNA, protein or polypeptide which, when produced in plant cells wherein said sterility RNA, protein or polypeptide is produced, prevents the activity of said sterility RNA, protein or polypeptide, and a coregulating promoter which is selected from the group consisting of a promoter directing expression of said coregulating DNA in non-stamen cells of said plant,Type: GrantFiled: December 10, 1999Date of Patent: February 5, 2002Assignee: Aventis CropScience N.V.Inventors: Frank Michiels, Johan Botterman, Marc Cornelissen
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Patent number: 6333449Abstract: The invention relates to an elite event glufosinate tolerant rice plant transformed with a bar gene, such as a 35S-bar gene, where the gene is inserted into the location defined by SEQ ID [No] NO: 9 within the rice genome, and methods of making and using the glufosinate tolerant rice plant.Type: GrantFiled: November 3, 1998Date of Patent: December 25, 2001Assignee: Plant Genetic Systems, N.V.Inventors: Frank Michiels, Kirk Johnson
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Patent number: 6299754Abstract: An apparatus is disclosed for electrolytic desilvering of photographic processing solutions, more particularly fixing solutions or bleach-fixing solutions, comprising an electrolysis unit equiped with a monitoring system comprising a cathode, an anode and a reference electrode, characterized in that said reference electrode is a pH sensitive electrode. The desilvering is preferably performed under potentiostatic conditions. Whe using a pH sensitive reference electrode the cathodic plating potential is automatically corrected for pH changes. A preferred pH sensitive electrode is a glass electrode.Type: GrantFiled: May 22, 1996Date of Patent: October 9, 2001Assignee: Agfa-GevaertInventors: Patrick Mertens, Benny Jansen, Werner Van de Wynckel, Frank Michiels
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Patent number: 6238853Abstract: A method of processing has been described for a light-sensitive black-and-white silver halide photographic material comprising the distinct steps of developing, fixing, rinsing and drying, wherein during said processing said developer comprises, besides one or more developing agent(s), one or more agent(s) preventing oxidation thereof and agent(s) providing pH buffering in running equilibrium conditions during said processing, at least one agent preventing silver dissolution and at least one silver complexing agent, characterized in that said agent preventing silver dissolution, if present in an amount of 50 mg/l of developer, makes silver content of the developer decrease in an amount of more than 50% versus in the absence thereof, without loss in speed in an amount of more than 0.10 log Exposure after processing in said developer composition; said silver complexing agent makes silver content of the said developer increase in an amount of more than 1 mg per liter per mmole of said complexing agent.Type: GrantFiled: June 6, 2000Date of Patent: May 29, 2001Assignee: Agfa-GevaertInventors: Govert De Baecke, Benny Jansen, Frank Michiels, Johan Loccufier, Ton Rutges
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Patent number: 6238854Abstract: A black-and-white silver halide developer composition has been disclosed comprising, besides one or more developing agent(s), agent(s) preventing oxidation thereof and agent(s) providing pH buffering, at least one silver complexing agent, characterized in that said silver complexing agent has a silver complexing stability ratio of at least 70% and, besides said silver complexing agent, at least one agent preventing silver dissolution characterized in that said agent preventing silver dissolution, if present in an amount of 50 mg/l of developer, makes silver content of the developer decrease in an amount of more than 50% versus in the absence thereof, without loss in speed in an amount of more than 0.10 log Exposure after processing in said developer composition.Type: GrantFiled: June 6, 2000Date of Patent: May 29, 2001Assignee: Agfa-GevaertInventors: Benny Jansen, Govert De Baecke, Frank Michiels, Johan Loccufier, Ton Rutges
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Patent number: 6102589Abstract: A method of processing an exposed black-and-white silver halide photographic film material, the method having the steps of developing in a developer solution, fixing in a fixer solution, replenishing of fixer and developer solution, rinsing in a washing solution and drying, characterized in that fixing is performed in one step and under such conditions that a "silver equilibrium ratio" of less than 2.0 is maintained, the said ratio being defined as the ratio between actual by the film material in the rinsing step through carry-over (cross-over) of silver from the fixing solution to the washing solution and amount of silver brought into the washing solution and the total amount of silver that theoretically could be brought into the washing solution by the film material by such carry-over; a "fixer to film silver ratio" of less than 0.Type: GrantFiled: January 22, 1999Date of Patent: August 15, 2000Assignee: Agfa-Gevaert, N.V.Inventors: Frank Michiels, Benedictus Jansen
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Patent number: 6083672Abstract: A method of processing an exposed black-and-white silver halide light-sensitive photographic material has been disclosed, said method comprising the steps of developing in a developer solution, followed by fixing in a fixer solution, comprising a hardening agent, preferably a compound providing aluminum ions, and wherein, in running equilibrium conditions, said fixer solution has a pH of at least 4.3, further adding to said fixer a fixer replenisher at a rate of from 0 ml/m.sup.2 up to 300 ml/m.sup.2 ; followed by rinsing and drying, wherein rinsing between developing and fixing is excluded and wherein an .alpha.Type: GrantFiled: September 23, 1998Date of Patent: July 4, 2000Assignee: Agfa-Gevaert, N.V.Inventors: Andre Roefs, Benedictus Jansen, Frank Michiels
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Patent number: 6066441Abstract: A method is disclosed of processing an exposed black-and-white light-sensitive silver halide photographic material having silver halide, coated in an amount, expressed as an equivalent amount of silver nitrate of less than 6 g/m.sup.2 comprising the steps of developing, fixing, rinsing and drying, making use in the developing step of an ascorbic acid type developer and of an equivalent developer replenisher providing a regeneration amount of less than 150 ml/m.sup.2, characterized in that the said material has a buffering capacity of less than 6 mmole/m.sup.2, wherein said buffering capacity is defined as the amount of alkali, expressed in mmole/square meter, required to bridge across pH differences between the material and the developer.Type: GrantFiled: May 3, 1999Date of Patent: May 23, 2000Assignee: Agfa-Gevaert, N.V.Inventors: Benedictus Jansen, Freddy Henderickx, Ann Verbeeck, Frank Michiels
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Patent number: 6025546Abstract: A plant having in the nuclear genome of its cells foreign DNA comprisinga male-sterility gene comprising:a male-sterility DNA encoding a sterility RNA, protein or polypeptide which, when produced or overproduced in a stamen cell of the plant, significantly disturbs the metabolism, functioning and/or development of the stamen cell, and,a sterility promoter directing expression of the male-sterility DNA selectively in specific stamen cells of said plant, the male-sterility DNA being in the same transcriptional unit as, and under the control of, the sterility promoter, anda coregulating gene comprising:a coregulating DNA encoding a coregulating RNA, protein or polypeptide which is capable, when produced in plant cells wherein said sterility RNA, protein or polypeptide is produced, of sufficiently preventing the activity of said sterility RNA, protein or polypeptide,whereby said coregulating DNA is in a transcriptional unit which is different from the transcriptional unit of said sterility DNA.Type: GrantFiled: November 12, 1997Date of Patent: February 15, 2000Assignee: Plant Genetic System, N.V.Inventors: Frank Michiels, Johan Botterman, Marc Cornelissen
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Patent number: 5951844Abstract: An apparatus for de-silvering silver-containing solutions comprises an electrolytic cell (10) having an anode (20), a cathode (30) and a reference electrode (45) positioned adjacent the cathode (30), and electrical power supply control means (41) for controlling the supply of electrical power to the anode (20) and the cathode (30). Operation of the cell (10) is controlled potentiostatically while the current exceeds a certain threshold value and the current is controlled galvanostatically at that threshold (minimum) value in circumstances in which the potentiostatic control would result in a current below the threshold value.Type: GrantFiled: April 10, 1997Date of Patent: September 14, 1999Assignee: Agfa GevaertInventors: Benedictus Jansen, Werner Van de Wynckel, Frank Michiels