Patents by Inventor Frank Mikkelsen

Frank Mikkelsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protease Variants and Compositions
    Publication number: 20110028378
    Abstract: The present invention relates to enzymes produced by mutating the genes for a number of subtilases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved wash performance in any detergent in comparison to their wild type parent enzymes.
    Type: Application
    Filed: October 14, 2010
    Publication date: February 3, 2011
    Applicant: Novozymes A/S
    Inventors: Peter Kamp Hansen, Peter Bauditz, Frank Mikkelsen, Kim Vilbour Andersen
  • Protease Variants and Compositions
    Publication number: 20090099056
    Abstract: The present invention relates to enzymes produced by mutating the genes for a number of subtilases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved wash performance in any detergent in comparison to their wild type parent enzymes.
    Type: Application
    Filed: September 26, 2007
    Publication date: April 16, 2009
    Applicant: Novozymes A/S
    Inventors: Peter Kamp Hansen, Peter Bauditz, Frank Mikkelsen, Kim Vilbour Andersen
  • Protease variants and compositions
    Patent number: 7288401
    Abstract: The present invention relates to enzymes produced by mutating the genes for a number of subtilases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved wash performance in any detergent in comparison to their wild type parent enzymes.
    Type: Grant
    Filed: April 12, 2005
    Date of Patent: October 30, 2007
    Assignee: Novozymes A/S
    Inventors: Peter Kamp Hansen, Peter Bauditz, Frank Mikkelsen, Kim Vilbour Andersen
  • Protease variants and compositions
    Patent number: 7026153
    Abstract: The present invention relates to protease subtilase enzyme, characterized by an insertion in at least one active site loop. The enzymes exhibit improved wash performance in a detergent in comparison to its parent enzyme if it is a subtilase variant.
    Type: Grant
    Filed: March 31, 2003
    Date of Patent: April 11, 2006
    Assignee: Novozymes A/S
    Inventors: Peter Kamp Hansen, Peter Bauditz, Frank Mikkelsen
  • Protease variants and compositions
    Publication number: 20050239185
    Abstract: The present invention relates to enzymes produced by mutating the genes for a number of subtilases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved wash performance in any detergent in comparison to their wild type parent enzymes.
    Type: Application
    Filed: April 12, 2005
    Publication date: October 27, 2005
    Applicant: Novozymes A/S
    Inventors: Peter Hansen, Peter Bauditz, Frank Mikkelsen, Kim Andersen
  • Protease variants and compositions
    Patent number: 6921657
    Abstract: The present invention relates to enzymes produced by mutating the genes for a number of subtilases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved wash performance in any detergent in comparison to their wild type parent enzymes.
    Type: Grant
    Filed: January 3, 2003
    Date of Patent: July 26, 2005
    Assignee: Novozymes A/S
    Inventors: Peter Kamp Hansen, Peter Bauditz, Frank Mikkelsen, Kim Vilbour Andersen
  • Subtilase enzymes
    Patent number: 6780629
    Abstract: The present invention relates to subtilase enzymes of the I-S1 and I-S2 sub-groups having an additional amino acid in the active site loop (c) region from positions 125 to 132. The variant subtilases of the present invention exhibit improved wash performance in a detergent in comparison to its parent enzyme.
    Type: Grant
    Filed: September 13, 2002
    Date of Patent: August 24, 2004
    Assignee: Novozymes A/S
    Inventors: Peter Kamp Hansen, Peter Bauditz, Frank Mikkelsen, Kim Vilbour Andersen, Carsten Andersen, Mads Norregaard-Madsen
  • Subtilase enzymes having an improved wash performance on egg stains
    Patent number: 6777218
    Abstract: The present invention relates to novel subtilases having an improved wash performance on egg stains. The present invention also relates to isolated nucleic acid sequences encoding the subtilases, nucleic acid constructs, recombinant expression vectors, host cells comprising the nucleic acid construct, and methods for producing and using the subtilases of the invention. Further, the present invention relates to cleaning and detergent compositions comprising the subtilase enzymes of the invention as well as to use of such enzymes in detergent compositions and for removal of egg stains.
    Type: Grant
    Filed: March 23, 2000
    Date of Patent: August 17, 2004
    Assignees: Novozymes A/S, Maxygen, Inc
    Inventors: Frank Mikkelsen, Tina Sejersgård Fanø, Jon E. Ness, Mark D. Welch, Lorraine J. Giver, Jeremy S. Minshull, Torben V. Borchert, Joel Cherry
  • Subtilase enzymes
    Patent number: 6773907
    Abstract: The present invention relates to subtilase enzymes of the I-S1 and I-S2 sub-groups having an additional amino acid in the active site loop (b) region from positions 95 to 103. The variant subtilases of the present invention exhibit improved wash performance in a detergent in comparison to its parent enzyme.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: August 10, 2004
    Inventors: Peter Kamp Hansen, Peter Bauditz, Frank Mikkelsen, Kim Vilbour Andersen, Carsten Andersen, Mads Norregaard-Madsen
  • Subtilase variants having an improved wash performance on egg stains
    Patent number: 6727085
    Abstract: The present invention relates to the use of a subtilase variant for removal of egg stains from laundry or from hard surfaces, where the subtilase variant comprises at least one additional amino acid residue in the active site loop (b) region from position 95 to 103 (BASBPN numbering). These subtilase variants are useful exhibiting excellent or improved wash performance on egg stains when used in e.g. cleaning or detergent compositions, including automatic dishwash compositions. The present invention also relates to novel subtilase variants, to isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the variants of the invention. Further, the present invention relates to cleaning and detergent compositions comprising the variants of the invention.
    Type: Grant
    Filed: December 13, 2000
    Date of Patent: April 27, 2004
    Inventors: Tina Sejersgård Fanø, Frank Mikkelsen
  • Subtilase variants having an improved wash performance on egg stains
    Publication number: 20030199077
    Abstract: The present invention relates to the use of a subtilase variant for removal of egg stains from laundry or from hard surfaces, where the subtilase variant comprises at least one additional amino acid residue in the active site loop (b) region from position 95 to 103 (BASBPN numbering). These subtilase variants are useful exhibiting excellent or improved wash performance on egg stains when used in e.g. cleaning or detergent compositions, including automatic dishwash compositions. The present invention also relates to novel subtilase variants, to isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the variants of the invention. Further, the present invention relates to cleaning and detergent compositions comprising the variants of the invention.
    Type: Application
    Filed: December 13, 2000
    Publication date: October 23, 2003
    Inventors: Tina Sejersgard Fano, Frank Mikkelsen
  • Subtilase enzymes
    Publication number: 20030191038
    Abstract: The present invention relates to subtilase enzymes of the I-S1 and I-S2 sub-groups having an additional amino acid in the active site loop (c) region from positions 125 to 132. The variant subtilases of the present invention exhibit improved wash performance in a detergent in comparison to its parent enzyme.
    Type: Application
    Filed: September 13, 2002
    Publication date: October 9, 2003
    Applicant: Novozymes A/S
    Inventors: Peter Kamp Hansen, Peter Bauditz, Frank Mikkelsen, Kim Vilbour Andersen, Carsten Andersen, Mads Norregaard-Madsen
  • Protease variants and compositions
    Publication number: 20030180933
    Abstract: The present invention relates to protease subtilase enzyme, characterized by an insertion in at least one active site loop. The enzymes exhibit improved wash performance in a detergent in comparison to its parent enzyme if it is a subtilase variant.
    Type: Application
    Filed: March 31, 2003
    Publication date: September 25, 2003
    Applicant: Novozymes A/S
    Inventors: Peter Kamp Hansen, Peter Bauditz, Frank Mikkelsen
  • Protease variants and compositions
    Publication number: 20030176304
    Abstract: The present invention relates to enzymes produced by mutating the genes for a number of subtilases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved wash performance in any detergent in comparison to their wild type parent enzymes.
    Type: Application
    Filed: January 3, 2003
    Publication date: September 18, 2003
    Applicant: Novozymes A/S
    Inventors: Peter Kamp Hansen, Peter Bauditz, Frank Mikkelsen, Kim Vilbour Andersen
  • Subtilase enzymes
    Publication number: 20030171235
    Abstract: The present invention relates to subtilase enzymes of the I-S1 and I-S2 sub-groups having an additional amino acid in the active site loop (b) region from positions 95 to 103. The variant subtilases of the present invention exhibit improved wash performance in a detergent in comparison to its parent enzyme.
    Type: Application
    Filed: September 12, 2002
    Publication date: September 11, 2003
    Applicant: Novozymes A/S
    Inventors: Peter Kamp Hansen, Peter Bauditz, Frank Mikkelsen, Kim Vilbour Andersen, Carsten Andersen, Mads Norregaard-Madsen
  • Protease variants and compositions
    Patent number: 6605458
    Abstract: A protease subtilase enzyme, characterized by an insertion in at least one active site loop. The enzymes exhibit improved wash performance in a detergent in comparison to its parent enzyme if it is a subtilase variant.
    Type: Grant
    Filed: November 19, 1998
    Date of Patent: August 12, 2003
    Assignee: Novozymes A/S
    Inventors: Peter Kamp Hansen, Peter Bauditz, Frank Mikkelsen
  • Protease variants and compositions
    Patent number: 6558938
    Abstract: Enzymes produced by mutating the genes for a number of subtilases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved wash performance in any detergent in comparison to their wild type parent enzymes.
    Type: Grant
    Filed: February 29, 2000
    Date of Patent: May 6, 2003
    Assignee: Novozymes, A/S
    Inventors: Peter Kamp Hansen, Peter Bauditz, Frank Mikkelsen, Kim Vilbour Andersen
  • Protease variants and compositions
    Patent number: 6555355
    Abstract: Enzymes produced by mutating the genes for a number of subtilases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved wash performance in any detergent in comparison to their wild type parent enzymes.
    Type: Grant
    Filed: February 24, 2000
    Date of Patent: April 29, 2003
    Assignee: Novozymes, A/S
    Inventors: Peter Kamp Hansen, Peter Bauditz, Frank Mikkelsen, Kim Vilbour Andersen
  • Phage display for detergent enzyme activity
    Patent number: 6506566
    Abstract: The invention relates to a method of identifying enzymes suitable for use in detergents, especially the selection of specific enzyme variants among a large number of such variants created through random mutagenesis.
    Type: Grant
    Filed: December 18, 2000
    Date of Patent: January 14, 2003
    Assignee: Novozymes A/S
    Inventors: Peter Markvardsen, Mads Eskelund Bjornvad, Frank Mikkelsen, Borge Diderichsen
  • Phage display for detergent enzyme activity
    Publication number: 20020058246
    Abstract: The invention relates to a method of identifying enzymes suitable for use in detergents, especially the selection of specific enzyme variants among a large number of such variants created through random mutagenesis.
    Type: Application
    Filed: December 18, 2000
    Publication date: May 16, 2002
    Inventors: Peter Markvardsen, Mads Eskelund Bjornvad, Frank Mikkelsen, Borge Diderichsen