Patents by Inventor Frank P. Palopoli

Frank P. Palopoli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reducing reperfusion injury with 1,3-dihydro-4-methyl-5-(4-methylthio)benzoyl)-2H-imidazol-2-thione
    Patent number: 4868197
    Abstract: A sulfur analog of enoximone, 1,3-dihydro-4-methyl-5-[4-(methylthio)benzoyl]-2H-imidazol-2-thione, is reported to reduce reperfusion injury, the injry which occurs when molecular oxygen is reintroduced into an ischemic tissue. The compound could be used to prevent much of the damage which occurs to the heart of a heart attack victim.
    Type: Grant
    Filed: March 21, 1988
    Date of Patent: September 19, 1989
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Richard A. Schnettler, Richard C. Dage, J. Martin Grisar, Frank P. Palopoli
  • 4-Pyridylimidazolones and method of use
    Patent number: 4405628
    Abstract: This invention relates to aroylimidazole-2-ones and their acid and base addition salts as well as their use as cardiotonics in the treatment of cardiac failure.
    Type: Grant
    Filed: October 23, 1981
    Date of Patent: September 20, 1983
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Richard C. Dage, Frank P. Palopoli, Richard A. Schnettler, J. Martin Grisar
  • Process for preparing 2-(2,2-dicyclohexylethyl)piperidine
    Patent number: 4191828
    Abstract: 2-(2,2-Dicyclohexylethyl)piperidine is prepared via the catalytic hydrogenation of 2-(2,2-diphenylethenyl)pyridine in a single step. High yields are obtained using a rhodium supported catalyst.
    Type: Grant
    Filed: April 14, 1976
    Date of Patent: March 4, 1980
    Assignee: Richardson-Merrell Inc.
    Inventors: Stephen W. Horgan, Frank P. Palopoli, David L. Wenstrup
  • Process for preparing 2-(2,2-dicyclohexylethyl)piperidine
    Patent number: 4069222
    Abstract: 2-(2,2-Dicyclohexylethyl)piperidine is prepared via the catalytic hydrogenation of 2-(2,2-diphenylethenyl)pyridine in a single step. High yields are obtained using an anhydrous Raney nickel catalyst.
    Type: Grant
    Filed: April 14, 1976
    Date of Patent: January 17, 1978
    Assignee: Richardson-Merrell Inc.
    Inventors: Stephen W. Horgan, Frank P. Palopoli, Edward J. Schwoegler