Patents by Inventor Frank R. Korosec

Frank R. Korosec has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10405772
    Abstract: Techniques and systems for non-contrast enhanced magnetic resonance angiography and venography (MRAV) are described. For example, within one cardiac cycle of a subject, a single shot acquisition of non-suppressed arterial MR signals and a single shot acquisition of non-suppressed venous MR signals are employed. Radio frequency (RF) saturation pulses may be applied to one or more slabs such that MR signals indicative of venous blood that flows into the arterial imaging slice are substantially suppressed and MR signals indicative of arterial blood that flows in the venous imaging slice are substantially suppressed. The RF saturation pulses and the single shot acquisitions may be timed such that one or more of the single shot acquisitions occur during substantially steady state inflow of blood into the respective imaging slice. In this manner, k-space data may be acquired from arterial specific and venous specific imaging slices occurring within a single cardiac cycle.
    Type: Grant
    Filed: September 18, 2012
    Date of Patent: September 10, 2019
    Assignees: WISCONSIN ALUMNI RESEARCH FOUNDATION, INC., GENERAL ELECTRIC COMPANY
    Inventors: Frank R. Korosec, James H. Holmes, Daniel V. Litwiller, Mahdi Salmani Rahimi
  • Patent number: 9274197
    Abstract: A magnetic resonance imaging data sampling method includes randomly undersampling a first half of a k-space plane such that a plurality of points in the first half are sampled points and the remaining plurality of points in the first half are unsampled points. The method also includes determining, for each sampled point in the first half, a corresponding point in a second half of the k-space plane that corresponds to the point-wise complex conjugate location of the sampled point.
    Type: Grant
    Filed: November 30, 2012
    Date of Patent: March 1, 2016
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Kang Wang, Peng Lai, James Hartman Holmes, Frank R. Korosec
  • Publication number: 20140152303
    Abstract: A magnetic resonance imaging data sampling method includes randomly undersampling a first half of a k-space plane such that a plurality of points in the first half are sampled points and the remaining plurality of points in the first half are unsampled points. The method also includes determining, for each sampled point in the first half, a corresponding point in a second half of the k-space plane that corresponds to the point-wise complex conjugate location of the sampled point.
    Type: Application
    Filed: November 30, 2012
    Publication date: June 5, 2014
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Kang Wang, Peng Lai, James Hartman Holmes, Frank R. Korosec
  • Publication number: 20140081123
    Abstract: Techniques and systems for non-contrast enhanced magnetic resonance angiography and venography (MRAV) are described. For example, within one cardiac cycle of a subject, a single shot acquisition of non-suppressed arterial MR signals and a single shot acquisition of non-suppressed venous MR signals are employed. Radio frequency (RF) saturation pulses may be applied to one or more slabs such that MR signals indicative of venous blood that flows into the arterial imaging slice are substantially suppressed and MR signals indicative of arterial blood that flows in the venous imaging slice are substantially suppressed. The RF saturation pulses and the single shot acquisitions may be timed such that one or more of the single shot acquisitions occur during substantially steady state inflow of blood into the respective imaging slice. In this manner, k-space data may be acquired from arterial specific and venous specific imaging slices occurring within a single cardiac cycle.
    Type: Application
    Filed: September 18, 2012
    Publication date: March 20, 2014
    Applicants: GENERAL ELECTRIC COMPANY, WISCONSIN ALUMNI RESEARCH FOUNDATION, INC.
    Inventors: Frank R. Korosec, James H. Holmes, Daniel V. Litwiller, Mahdi Salmani Rahimi
  • Patent number: 6044290
    Abstract: A dynamic MRA study of a subject is performed using a 3D echo-planar imaging pulse sequence. Four phase encoding views are acquired for each pulse repetition period (TR) and this enables higher resolution images to be acquired without a reduction of temporal frame rate or a loss of image CNR.
    Type: Grant
    Filed: April 6, 1998
    Date of Patent: March 28, 2000
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Karl K Vigen, Charles A Mistretta, Thomas M Grist, Frank R Korosec, Richard Frayne
  • Patent number: 5873825
    Abstract: A dynamic MRA study of a subject is performed using a 3D fast gradient-recalled echo pulse sequence. The frame rate of the resulting series of reconstructed images is increased by sampling a central region of k-space at a higher rate than the peripheral regions of k-space. A difference image is produced by subtracting a mask formed by central region k-space sampling from a selected image frame formed by central region and peripheral regions k-space sampling.
    Type: Grant
    Filed: April 6, 1998
    Date of Patent: February 23, 1999
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Charles A Mistretta, Frank R Korosec, Thomas M Grist, Richard Frayne
  • Patent number: 5830143
    Abstract: A dynamic MRA study of a subject is performed using a 3D fast gradient-recalled echo pulse sequence that employs a non-selective RF excitation pulse. The frame rate of the resulting series of reconstructed images is increased by sampling a central region of k-space at a higher rate than the peripheral regions of k-space. The acquisition is gated using a cardiac trigger signal and the central region of k-space is acquired during diastole and the peripheral regions of k-space are acquired during systole. Image frames are reconstructed at each sampling of the central k-space region using the temporally nearest samples from the peripheral k-space regions. Two of the image frames are subtracted to form an MR angiogram.
    Type: Grant
    Filed: January 21, 1997
    Date of Patent: November 3, 1998
    Assignee: Wisconsin Alumnin Research Foundation
    Inventors: Charles M. Mistretta, Frank R. Korosec, Thomas M. Grist, Richard Frayne
  • Patent number: 5713358
    Abstract: A dynamic MRA study of a subject is performed using a 3D fast gradient-recalled echo pulse sequence. The frame rate of the resulting series of reconstructed images is increased by sampling a central region of k-space at a higher rate than the peripheral regions of k-space. Image frames are reconstructed at each sampling of the central k-space region using the temporally nearest samples from the peripheral k-space regions.
    Type: Grant
    Filed: March 26, 1996
    Date of Patent: February 3, 1998
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Charles A. Mistretta, Frank R. Korosec, Thomas M. Grist, Richard Frayne, Jason A. Polzin
  • Patent number: 5285158
    Abstract: An angiogram is produced using NMR fast pulse sequences in which the views are acquired in shots preceded by a preparatory pulse sequence. Each shot is acquired twice with differing preparatory pulse sequences and the resulting NMR data is subtracted to null the stationary tissues in the reconstructed image.
    Type: Grant
    Filed: August 6, 1992
    Date of Patent: February 8, 1994
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Charles A. Mistretta, Frank R. Korosec, David M. Weber, Thomas M. Grist
  • Patent number: 5204627
    Abstract: A magnetic resonance angiogram is produced by projecting a 3D array of motion sensitized NMR data. A mask which locates the vessels in the 3D array is produced by thresholding the NMR data, and this mask is combined with the 3D NMR data set to exclude signals produced by surrounding stationary tissues. An integration projection technique is used to produce the angiogram from the masked data set.
    Type: Grant
    Filed: March 14, 1991
    Date of Patent: April 20, 1993
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Charles A. Mistretta, Frank R. Korosec, David M. Weber
  • Patent number: 5031624
    Abstract: An NMR angiogram is produced using a line scan data acquisition. Each line of NMR data is acquired twice, once with a velocity sensitizing gradient having a positive first moment and once with a velocity sensitizing gradient having a negative first moment. The two signals from the acquisition are subtracted to cancel signals from stationary spins while enhancing signals from flowing spins. The magnitude of the velocity sensitizing gradient moment is changed during the cardiac cycle so that aliasing does not occur at high blood velocities and the signal strength does not drop too low at low blood velocities. An angiogram is produced by reconstructing an image from line scan data acquired from a series of slices.
    Type: Grant
    Filed: August 17, 1990
    Date of Patent: July 16, 1991
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Charles A. Mistretta, Frank R. Korosec