Abstract: A biological fluid analysis device including a biosensor is disclosed.

Abstract: A method for automatically processing a biological fluid is disclosed. The method includes the steps of obtaining a container having a biological fluid therein, providing a first signal and communicating with an automated control arrangement to establish flow of at least a portion of the biological fluid along a fluid flow path through a leukocyte depletion medium, providing a second signal and communicating with the automatic control arrangement to terminate flow along the fluid flow path wherein providing the second signal includes sensing the back pressure in the fluid flow path or the flow rate through the leukocyte depletion medium.

Abstract: An automated system for processing biological fluid includes a pressure differential generator, a biological fluid processing assembly, and an automated control arrangement coupled to at least one of the pressure differential generator and the biological fluid processing assembly. The automated system may include a porous medium, such as a red cell barrier medium, a leukocyte depletion medium, or a combination red cell barrier/leukocyte depletion medium. The automated system may also include a sensor producing a signal reflecting a parameter of fluid flow.

Abstract: The present invention provides for processing a biological fluid such as blood, to separate at least one component from the biological fluid, and to remove leukocytes from the separated component while returning the component depleted biological fluid to the source of the fluid. Illustratively, blood is obtained from a source such as a donor, and platelets are separated from the bold. Gas is separated from the flow path of the separated platelets, which are depleted of leukocytes, while platelet depleted blood is returned to the donor.

Abstract: An automated system for processing biological fluid includes a pressure differential generator, a biological fluid processing assembly including a first container operatively associated with the pressure differential generator, at least one satellite container in fluid communication with the first container and a porous medium including a leukocyte depletion medium interposed between the first container and the satellite container and a sensor downstream of the porous medium for sensing and providing a signal reflecting the presence of red blood cells downstream of the porous medium. An automated control arrangement is coupled to the sensor to receive the signal from the sensor and coupled to at least one of the pressure differential generator and the biological fluid processing assembly to control flow between the first container and the satellite container.

Abstract: A method for processing a biological fluid comprises separating a transition zone material from the biological fluid; processing the transition zone material to form a supernatant layer which includes platelets and a sediment layer which includes red blood cells; and separating the supernatant layer from the sediment layer by passing the supernatant layer through a porous medium. A method for processing a biological fluid comprises passing a biological fluid through a leukocyte depletion filter assembly and into a container downstream of the filter assembly; and separating gas displaced by the biological fluid into the downstream container by passing the gas from the container through a liquid barrier medium in a gas collection and displacement loop. Devices for carrying out the methods are also disclosed.

Abstract: A method for removing undesirable material including leukocytes from a biological fluid in an extracorporeal circuit comprises passing a leukocyte containing biological fluid from a patient into a container; passing a portion of biological fluid from the container through a recirculation loop including a filter assembly for removing leukocytes to leukocyte deplete the biological fluid and to pass the portion of leukocyte-depleted biological fluid into the container; passing additional leukocyte containing biological fluid from a patient into the container so that the additional fluid is mixed with leukocyte depleted biological fluid in the container to provide a mixture including leukocyte depleted and non-leukocyte depleted biological fluid; passing the mixture of biological fluid from the container; passing a portion of the mixture to the patient while passing another portion of the mixture through the recirculation loop.

Abstract: Methods, systems and devices for processing fluid provide for contacting the fluid with iodine.

Abstract: An expressor for varying the amount of fluid in a variable-volume container connected to at least one conduit includes a housing defining an enclosed chamber which can accommodate the container. The housing has at least one opening through which a conduit can extend. A pressure regulating mechanism is coupled to the housing to vary the pressure of fluid in the chamber and thereby vary the volume of the container.

Abstract: Methods and systems for processing a biological fluid and treating a separated component of the biological fluid are disclosed.

Abstract: Methods, systems, and devices for processing a biological fluid including leukocytes during cardioplegia are disclosed. A method for processing a biological fluid including leukocytes comprises passing a cardioplegia fluid through a bacterial removing filter; mixing the cardioplegia fluid with the biological fluid including leukocytes to form a cardioplegia mixture; and, passing the cardioplegia mixture through a cardioplegia mixture filter assembly to produce a leukocyte-depleted cardioplegia mixture, said assembly comprising a porous medium to remove leukocytes from the cardioplegia mixture.

Abstract: Methods and devices for treating transition zone material are disclosed. Transition zone material is processed to form a supernatant layer which includes platelets and a sediment layer which includes red blood cells, and the supernatant layer is separated from the sediment layer by passing the supernatant layer through a porous medium. Once the supernatant layer has been separated from the sediment layer, gas may be separated from the supernatant layer.

Abstract: Processes and systems for combining multiple units of a biological fluid in independent containers into a single container are disclosed.

Abstract: Processes and systems for combining multiple units of a biological fluid in independent containers into a single container are disclosed.

Abstract: The invention involves a method and apparatus for treating and administering biological fluids, particularly hyperconcentrated biological fluids.

Abstract: A device for reducing the amount of particulate contaminant in a liquid is provided which includes a hollow elongate member having first and second openings and filter means, preferably depth filter means, positioned in the elongate member, the filter means in combination with the elongate member defining a reservoir between the filter means and the first opening. The device is intended to be used with means associated with the first opening for generating a pressure differential between the interior of the elongate member and the exterior thereof whereby a liquid containing particulate contaminant may be introduced into the reservoir in the elongate member through the second opening, particulate contaminant being trapped within the filter means and a liquid with a reduced particulate contaminant may be removed from the elongate member through the second opening.

Abstract: The method hereof, conducted at the factory or site of printing of the wall covering, advantageously uses the same work or printing station reference that accurately positions the imprinted pattern on the wall covering substrate for the positioning of cutting means effective to sever said substrate free of the opposite unprinted selvage areas. Thus, although the substrate, which typically is a 100-foot strip, may be inadvertently slightly misaligned from a perfectly straight orientation, the cutting means nevertheless effectively moves along that path which accurately slits free the selvages of the "misaligned" substrate because it is guided by said imprinting reference during said movement.