Abstract: A ventilator (1) with a control unit (49). The control unit (49) controls the inhalation valve (41) and the exhalation valve (43) in order to raise an inhalation pressure level from a first pressure level to a predefined second pressure level and to maintain the inhalation pressure level for a first predefined time period and the control unit (49) controls the inhalation valve (41) and the exhalation valve (43) to raise the second pressure level to a predefined third pressure level and to maintain the third pressure level for a second predefined time period. The control unit (49) takes into consideration predefined values (80) for controlling the pressure levels and for controlling the time periods.

Abstract: An apparatus and process (100) for processing data (101, 102, 103) obtained by an imaging technique enables an improvement of a determination of quality and quantity of ventilation of the lungs. By including a correction data set KDS determined during one or more inhalation phases, it is determined which effects result from adjustments of pressure levels (PEEPA, PEEPB) (81, 82) during ventilation. The result of the determination is provided as an output signal (900).

Abstract: A ventilator (100) ventilates a patient (102) by a high-flow oxygen therapy via a tube system (104). The ventilator has at least one sensor element (110), at least one actuatable inhalation valve or exhalation valve (120) and a control unit (130). The sensor element is arranged and configured to determine and to output a measured variable (112) within the tube system. The measured variable indicates a gas flow within the tube system. The actuatable inhalation valve or exhalation valve is arranged and configured to make possible a flow of a breathing gas from a ventilation circuit (107) of the ventilator. The control unit regulates a ventilation pressure provided by the ventilator via the at least one sensor element and the at least one inhalation valve or exhalation valve such that a predefined maximum pressure is not exceeded in a predefined area (140) of the tube system.

Abstract: A device and a process determine a value indicative of a respective regional compliance of lungs of a patient (P) in a plurality of different regions of the lungs. An airway pressure sensor (3) measures a value indicative of the pressure (Paw), which is variable over time, at the airway of the patient (P). A difference between the end-inspiratory transpulmonary pressure and the end-expiratory transpulmonary pressure is determined. An EIT measuring device (17) measures by electrical impedance tomography (EIT) a change in volume of a lung region. The difference between the end-inspiratory volume and the end-expiratory volume of the lung region is determined with the use of signals of the EIT measuring device (17). A quotient of the volume difference for the region in question and the pressure difference present at the lungs is calculated as the value indicative of the regional compliance of the lung region.

Abstract: A ventilator (1) with a control unit (49). The control unit (49) controls the inhalation valve (41) and the exhalation valve (43) in order to raise an inhalation pressure level from a first pressure level to a predefined second pressure level and to maintain the inhalation pressure level for a first predefined time period and the control unit (49) controls the inhalation valve (41) and the exhalation valve (43) to raise the second pressure level to a predefined third pressure level and to maintain the third pressure level for a second predefined time period. The control unit (49) takes into consideration predefined values (80) for controlling the pressure levels and for controlling the time periods.

Abstract: A process is provided for operating a respirator and/or anesthesia device in the APRV mode with at least one pressure release phase with the step of setting a first point in time for terminating the pressure release phase. The process includes measuring the electrical impedance and/or impedance change of the lungs and setting the first point in time such that the measured impedance and/or impedance change are taken into account. A device is provided for carrying out the process according to the present invention.

Abstract: A method for managing patient ventilator operation includes receiving data representing one or more hemodynamic parameters. In response to the received data representing the one or more hemodynamic parameters, one or more commands are provided for adaptively altering ventilator operation.

Abstract: A method is provided for automatically controlling a ventilation or breathing system with a ventilation unit (7), which is controlled by a control unit (5), in order to deliver an assist pressure preset by the control unit, wherein the current values of the tidal volume flow Flow(t) and those of the volume V(t) are detected in the control unit. The control unit (5) may carry out a proportionally assisting ventilation method (PAV: Proportional Assist Ventilation) by a factor for a degree of compensation (PPSp) being selected by the control unit and by the parameters for the volume assist (VA) and the flow assist (FA) being determined by: VA=PPSp·?E FA=PPSp·?R, wherein ?E is the deviation of a measured or assumed elastance (Emeasured) of the patient from an ideal elastance (Eideal) and ?R is the deviation of a measured or assumed resistance (Rmeasured) of the patient from an ideal resistance (Rideal).

Abstract: A system and a method for synchronizing operation between a patient monitoring device and a patient treatment device are disclosed. The patient monitoring device and the patient treatment device are operatively connected via a network, for example, a patient area network (PAN) or a local area network (LAN). A controller with a display is configured to accept user input via a graphic user interface (GUI) and display a patient's physiological data and operating parameters of both the patient monitoring device and the patient treatment device. The operation is synchronized by starting to operate the patient monitoring device at a predetermined operating state of the patient treatment device, and delaying changes in the operating state of the patient treatment device, until the operation of the monitoring device is concluded or the operating state of the patient treatment device indicates an abort condition.

Abstract: The present invention relates to a process for isolating (?S,?R)-6-bromo-?-[2-(dimethylamino)ethyl]-2-methoxy-?-1-naphthalenyl-?-phenyl-3-quinolineethanol from a mixture of stereoisomeric forms of 6-bromo-?-[2-(dimethylamino)ethyl]-2-methoxy-?-1-naphthalenyl-?-phenyl-3-quinolineethanol by optical resolution with chiral 4-hydroxydinaphtho[2,1-d:1?,2?-f][1,3,2]dioxaphosphepin 4-oxide or a derivative thereof, in particular (11bR)-4-hydroxydinaphtho[2,1-d:1?,2?-f][1,3,2]dioxaphosphepin 4-oxide, as resolution agent.

Abstract: A method for operating an anesthesia/ventilation apparatus (11) avoids cardiogenic triggering of a triggered ventilation stroke. An apparatus (11) for carrying out the method of the invention is also disclosed.

Abstract: The present invention relates to a process for isolating (?S,?R)-6-bromo-?-[2-(dimethylamino)ethyl]-2-methoxy-?-1-naphthalenyl-?-phenyl-3-quinolineethanol from a mixture of stereoisomeric forms of 6-bromo-?-[2-(dimethylamino)ethyl]-2-methoxy-?-1-naphthalenyl-?-phenyl-3-quinolineethanol by optical resolution with chiral 4-hydroxydinaphtho[2,1-d:1?,2?-f][1,3,2]dioxaphosphepin 4-oxide or a derivative thereof, in particular (11bR)-4-hydroxydinaphtho[2,1-d:1?,2?-f][1,3,2]dioxaphosphepin 4-oxide, as resolution agent.

Abstract: The present invention relates to a process for isolating (?S,?R)-6-bromo-?-[2-(dimethylamino)ethyl]-2-methoxy-?-1-naphthalenyl-?-phenyl-3-quinolineethanol from a mixture of stereoisomeric forms of 6-bromo-?-[2-(dimethylamino)ethyl]-2-methoxy-?-1-naphthalenyl-?-phenyl-3-quinolineethanol by optical resolution with chiral 4-hydroxydinaphtho[2,1-d:1?,2?-f][1,3,2]dioxaphosphepin 4-oxide or a derivative thereof, in particular (11bR)-4-hydroxydinaphtho[2,1-d:1?,2?-f][1,3,2]dioxaphosphepin 4-oxide, as resolution agent.

Abstract: A system and a method for synchronizing operation between a patient monitoring device and a patient treatment device are disclosed. The patient monitoring device and the patient treatment device are operatively connected via a network, for example, a patient area network (PAN) or a local area network (LAN). A controller with a display is configured to accept user input via a graphic user interface (GUI) and display a patient's physiological data and operating parameters of both the patient monitoring device and the patient treatment device. The operation is synchronized by starting to operate the patient monitoring device at a predetermined operating state of the patient treatment device, and delaying changes in the operating state of the patient treatment device, until the operation of the monitoring device is concluded or the operating state of the patient treatment device indicates an abort condition.

Abstract: A process is provided for operating a respirator and/or anesthesia device in the APRV mode with at least one pressure release phase with the step of setting a first point in time for terminating the pressure release phase. The process includes measuring the electrical impedance and/or impedance change of the lungs and setting the first point in time such that the measured impedance and/or impedance change are taken into account. A device is provided for carrying out the process according to the present invention.

Abstract: A method is provided for automatically controlling a ventilation or breathing system with a ventilation unit (7), which is controlled by a control unit (5), in order to deliver an assist pressure preset by the control unit, wherein the current values of the tidal volume flow Flow(t) and those of the volume V(t) are detected in the control unit. The control unit (5) may carry out a proportionally assisting ventilation method (PAV: Proportional Assist Ventilation) by a factor for a degree of compensation (PPSp) being selected by the control unit and by the parameters for the volume assist (VA) and the flow assist (FA) being determined by: VA=PPSp·?E FA=PPSp·?R, wherein ?E is the deviation of a measured or assumed elastance (Emeasured) of the patient from an ideal elastance (Eideal) and ?R is the deviation of a measured or assumed resistance (Rmeasured) of the patient from an ideal resistance (Rideal).

Abstract: A method for operating an anesthesia/ventilation apparatus (11) avoids cardiogenic triggering of a triggered ventilation stroke. An apparatus (11) for carrying out the method of the invention is also disclosed.

Abstract: The present invention relates to a process for isolating (?S,?R)-6-bromo-?-[2-(dimethylamino)ethyl]-2-methoxy-?-1-naphthalenyl-?-phenyl-3-quinolineethanol from a mixture of stereoisomeric forms of 6-bromo-?-[2-(dimethylamino)ethyl]-2-methoxy-?-1-naphthalenyl-?-phenyl-3-quinolineethanol by optical resolution with chiral 4-hydroxydinaphtho[2,1-d:1?,2?-f][1,3,2]dioxaphosphepin 4-oxide or a derivative thereof, in particular (11bR)-4-hydroxydinaphtho[2,1-d:1?,2?-f][1,3,2]dioxaphosphepin 4-oxide, as resolution agent.

Abstract: A method for managing patient ventilator operation includes receiving data representing one or more hemodynamic parameters. In response to the received data representing the one or more hemodynamic parameters, one or more commands are provided for adaptively altering ventilator operation.