Patents by Inventor Frank Ralfs

Frank Ralfs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11925757
    Abstract: A ventilator (1) with a control unit (49). The control unit (49) controls the inhalation valve (41) and the exhalation valve (43) in order to raise an inhalation pressure level from a first pressure level to a predefined second pressure level and to maintain the inhalation pressure level for a first predefined time period and the control unit (49) controls the inhalation valve (41) and the exhalation valve (43) to raise the second pressure level to a predefined third pressure level and to maintain the third pressure level for a second predefined time period. The control unit (49) takes into consideration predefined values (80) for controlling the pressure levels and for controlling the time periods.
    Type: Grant
    Filed: March 4, 2021
    Date of Patent: March 12, 2024
    Assignee: Drägerwerk AG & Co. KGaA
    Inventor: Frank Ralfs
  • Patent number: 9981095
    Abstract: A process is provided for operating a respirator and/or anesthesia device in the APRV mode with at least one pressure release phase with the step of setting a first point in time for terminating the pressure release phase. The process includes measuring the electrical impedance and/or impedance change of the lungs and setting the first point in time such that the measured impedance and/or impedance change are taken into account. A device is provided for carrying out the process according to the present invention.
    Type: Grant
    Filed: August 27, 2008
    Date of Patent: May 29, 2018
    Assignee: DRÄGERWERK AG & CO. KGAA
    Inventors: Frank Ralfs, Eckhard Teschner
  • Patent number: 9233222
    Abstract: A method for managing patient ventilator operation includes receiving data representing one or more hemodynamic parameters. In response to the received data representing the one or more hemodynamic parameters, one or more commands are provided for adaptively altering ventilator operation.
    Type: Grant
    Filed: June 27, 2007
    Date of Patent: January 12, 2016
    Assignee: Draeger Medical Systems, Inc.
    Inventors: Joseph Elaz, Wolfgang Scholz, Samuel Cavallaro, Jay Butterbrodt, Frank Ralfs
  • Patent number: 8950399
    Abstract: A method is provided for automatically controlling a ventilation or breathing system with a ventilation unit (7), which is controlled by a control unit (5), in order to deliver an assist pressure preset by the control unit, wherein the current values of the tidal volume flow Flow(t) and those of the volume V(t) are detected in the control unit. The control unit (5) may carry out a proportionally assisting ventilation method (PAV: Proportional Assist Ventilation) by a factor for a degree of compensation (PPSp) being selected by the control unit and by the parameters for the volume assist (VA) and the flow assist (FA) being determined by: VA=PPSp·?E FA=PPSp·?R, wherein ?E is the deviation of a measured or assumed elastance (Emeasured) of the patient from an ideal elastance (Eideal) and ?R is the deviation of a measured or assumed resistance (Rmeasured) of the patient from an ideal resistance (Rideal).
    Type: Grant
    Filed: November 5, 2008
    Date of Patent: February 10, 2015
    Assignee: Dräger Medical GmbH
    Inventors: Thomas Handzsuj, Ernst Schubert, Frank Ralfs, Marcus Eger
  • Patent number: 8485981
    Abstract: A system and a method for synchronizing operation between a patient monitoring device and a patient treatment device are disclosed. The patient monitoring device and the patient treatment device are operatively connected via a network, for example, a patient area network (PAN) or a local area network (LAN). A controller with a display is configured to accept user input via a graphic user interface (GUI) and display a patient's physiological data and operating parameters of both the patient monitoring device and the patient treatment device. The operation is synchronized by starting to operate the patient monitoring device at a predetermined operating state of the patient treatment device, and delaying changes in the operating state of the patient treatment device, until the operation of the monitoring device is concluded or the operating state of the patient treatment device indicates an abort condition.
    Type: Grant
    Filed: June 25, 2008
    Date of Patent: July 16, 2013
    Assignee: Draeger Medical Systems, Inc.
    Inventor: Frank Ralfs
  • Patent number: 8350040
    Abstract: The present invention relates to a process for isolating (?S,?R)-6-bromo-?-[2-(dimethylamino)ethyl]-2-methoxy-?-1-naphthalenyl-?-phenyl-3-quinolineethanol from a mixture of stereoisomeric forms of 6-bromo-?-[2-(dimethylamino)ethyl]-2-methoxy-?-1-naphthalenyl-?-phenyl-3-quinolineethanol by optical resolution with chiral 4-hydroxydinaphtho[2,1-d:1?,2?-f][1,3,2]dioxaphosphepin 4-oxide or a derivative thereof, in particular (11bR)-4-hydroxydinaphtho[2,1-d:1?,2?-f][1,3,2]dioxaphosphepin 4-oxide, as resolution agent.
    Type: Grant
    Filed: September 6, 2011
    Date of Patent: January 8, 2013
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Frank Ralf Porstmann, Stefan Horns, Thomas Bader
  • Patent number: 8201558
    Abstract: A method for operating an anesthesia/ventilation apparatus (11) avoids cardiogenic triggering of a triggered ventilation stroke. An apparatus (11) for carrying out the method of the invention is also disclosed.
    Type: Grant
    Filed: July 3, 2008
    Date of Patent: June 19, 2012
    Assignee: Draeger Medical GmbH
    Inventor: Frank Ralfs
  • Publication number: 20110319623
    Abstract: The present invention relates to a process for isolating (?S,?R)-6-bromo-?-[2-(dimethylamino)ethyl]-2-methoxy-?-1-naphthalenyl-?-phenyl-3-quinolineethanol from a mixture of stereoisomeric forms of 6-bromo-?-[2-(dimethylamino)ethyl]-2-methoxy-?-1-naphthalenyl-?-phenyl-3-quinolineethanol by optical resolution with chiral 4-hydroxydinaphtho[2,1-d:1?,2?-f][1,3,2]dioxaphosphepin 4-oxide or a derivative thereof, in particular (11bR)-4-hydroxydinaphtho[2,1-d:1?,2?-f][1,3,2]dioxaphosphepin 4-oxide, as resolution agent.
    Type: Application
    Filed: September 6, 2011
    Publication date: December 29, 2011
    Inventors: Frank Ralf PORSTMANN, Stefan Horns, Thomas Bader
  • Patent number: 8039628
    Abstract: The present invention relates to a process for isolating (?S,?R)-6-bromo-?-[2-(dimethylamino)ethyl]-2-methoxy-?-1-naphthalenyl-?-phenyl-3-quinolineethanol from a mixture of stereoisomeric forms of 6-bromo-?-[2-(dimethylamino)ethyl]-2-methoxy-?-1-naphthalenyl-?-phenyl-3-quinolineethanol by optical resolution with chiral 4-hydroxydinaphtho[2,1-d:1?,2?-f][1,3,2]dioxaphosphepin 4-oxide or a derivative thereof, in particular (11bR)-4-hydroxydinaphtho[2,1-d:1?,2?-f][1,3,2]dioxaphosphepin 4-oxide, as resolution agent.
    Type: Grant
    Filed: May 22, 2006
    Date of Patent: October 18, 2011
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Frank Ralf Porstmann, Stefan Horns, Thomas Bader
  • Publication number: 20090326389
    Abstract: A system and a method for synchronizing operation between a patient monitoring device and a patient treatment device are disclosed. The patient monitoring device and the patient treatment device are operatively connected via a network, for example, a patient area network (PAN) or a local area network (LAN). A controller with a display is configured to accept user input via a graphic user interface (GUI) and display a patient's physiological data and operating parameters of both the patient monitoring device and the patient treatment device. The operation is synchronized by starting to operate the patient monitoring device at a predetermined operating state of the patient treatment device, and delaying changes in the operating state of the patient treatment device, until the operation of the monitoring device is concluded or the operating state of the patient treatment device indicates an abort condition.
    Type: Application
    Filed: June 25, 2008
    Publication date: December 31, 2009
    Applicant: DRAEGER MEDICAL SYSTEMS, INC.
    Inventor: Frank Ralfs
  • Publication number: 20090114222
    Abstract: A process is provided for operating a respirator and/or anesthesia device in the APRV mode with at least one pressure release phase with the step of setting a first point in time for terminating the pressure release phase. The process includes measuring the electrical impedance and/or impedance change of the lungs and setting the first point in time such that the measured impedance and/or impedance change are taken into account. A device is provided for carrying out the process according to the present invention.
    Type: Application
    Filed: August 27, 2008
    Publication date: May 7, 2009
    Applicant: DRAGER MEDICAL AG & CO. KG
    Inventors: Frank Ralfs, Eckhard Teschner
  • Publication number: 20090007916
    Abstract: A method for operating an anesthesia/ventilation apparatus (11) avoids cardiogenic triggering of a triggered ventilation stroke. An apparatus (11) for carrying out the method of the invention is also disclosed.
    Type: Application
    Filed: July 3, 2008
    Publication date: January 8, 2009
    Inventor: Frank Ralfs
  • Publication number: 20080200683
    Abstract: The present invention relates to a process for isolating (?S,?R)-6-bromo-?-[2-(dimethylamino)ethyl]-2-methoxy-?-1-naphthalenyl-?-phenyl-3-quinolineethanol from a mixture of stereoisomeric forms of 6-bromo-?-[2-(dimethylamino)ethyl]-2-methoxy-?-1-naphthalenyl-?-phenyl-3-quinolineethanol by optical resolution with chiral 4-hydroxydinaphtho[2,1-d:1?,2?-f][1,3,2]dioxaphosphepin 4-oxide or a derivative thereof, in particular (11bR)-4-hydroxydinaphtho[2,1-d:1?,2?-f][1,3,2]dioxaphosphepin 4-oxide, as resolution agent.
    Type: Application
    Filed: May 22, 2006
    Publication date: August 21, 2008
    Inventors: Frank Ralf Porstmann, Stefan Horns, Thomas Bader
  • Publication number: 20080000479
    Abstract: A method for managing patient ventilator operation includes receiving data representing one or more hemodynamic parameters. In response to the received data representing the one or more hemodynamic parameters, one or more commands are provided for adaptively altering ventilator operation.
    Type: Application
    Filed: June 27, 2007
    Publication date: January 3, 2008
    Inventors: Joseph Elaz, Wolfgang Scholz, Samuel Cavallaro, Jay Butterbrodt, Frank Ralfs