Abstract: The present invention is related to a compound comprising a cyclic peptide of formula (I) and an N-terminal modification group A attached to Xaa1, wherein Xaa1, Xaa2, Xaa3, Xaa4, Xaa5 and Xaa6 are each residues of an amino acid, Xaa7 is a residue of an amino thiol or an amino acid of formula, Yc is a cyclization element which is either present or absent, and the N-terminal modification group A is either a blocking group Abl or an amino acid Aaa.

Abstract: A tyre strip extrusion apparatus includes extruders and an extrusion head which includes a head housing having feed openings respectively connected to the extruders for feed of extrusion material. An injection moulding tool is connected to the head housing and includes a profile plate formed with an outlet opening which communicates with the feed openings for extrusion material to flow from the feed openings to the outlet opening for extruding a web from the extrusion material. Bearing against the head housing along a first parting surface is a first distributor plate. A second distributor plate is arranged upstream of the profile plate in flow direction of the extrusion material. The first distributor plate bears along a second parting surface against the second distributor plate. The first and second distributor plates are configured such that at least a majority of the material paths runs through the first and second parting surfaces.

Abstract: An extrusion device including at least one extruder having a screw cylinder, a screw shaft rotatably supported in the screw cylinder and an extruder outlet, an injection mould having an outlet nozzle determining the cross-sectional contour of the extruder, and an extrusion head arranged between the extruder outlet of the at least one extruder and the outlet nozzle of the injection mould, wherein at least one perforated plate arranged in the extruder head is provided, which has a plurality of passage openings, wherein the passage openings are designed to dam up extrusion material conveyed from the at least one extruder through the passage openings of the perforated plate differently into at least one first region of the perforated plate and at least one second region of the perforated plate, in such a way that the extrusion material is partly diverted from its preferential direction within a central section of the perforated plate, specifically increasingly into at least one edge section of the perforated plat

Abstract: The invention relates to a hose extrusion head for producing a hose (50), said head comprising a head housing, a duct (14) formed in the head housing (12) for supplying a hose material (22), a pin (16) which is arranged in the duct (14), a die (18) and at least one securing element (20). According to the invention, the securing element (20) is attached by one end (39) to the die (18) such that said end (39) follows the movement of the die (18).

Abstract: A tyre strip extrusion apparatus includes extruders and an extrusion head which includes a head housing having feed openings respectively connected to the extruders for feed of extrusion material. An injection moulding tool is connected to the head housing and includes a profile plate formed with an outlet opening which communicates with the feed openings for extrusion material to flow from the feed openings to the outlet opening for extruding a web from the extrusion material. Bearing against the head housing along a first parting surface is a first distributor plate. A second distributor plate is arranged upstream of the profile plate in flow direction of the extrusion material. The first distributor plate bears along a second parting surface against the second distributor plate. The first and second distributor plates are configured such that at least a majority of the material paths runs through the first and second parting surfaces.

Abstract: The invention relates to a hose extrusion head for producing a hose (50), said head comprising a head housing, a duct (14) formed in the head housing (12) for supplying a hose material (22), a pin (16) which is arranged in the duct (14), a die (18) and at least one securing element (20). According to the invention, the securing element (20) is attached by one end (39) to the die (18) such that said end (39) follows the movement of the die (18).

Abstract: A strand-form vehicle seal is equipped with a flexible reinforcement with a substantially U-cross section. The flexible reinforcement includes at least two different substances formed of individual sections of a nonmetallic, soft-elastic material together with individual sections of another nonmetallic, however dimensionally stable and hard or rigid material. The individual sections in the reinforcement are interrupted and disposed intermittently each alternating one after the other along the direction of the reinforcement. The rigid sections form the clamping portions of the reinforcement. The soft elastic sections disposed between them lend flexibility to the reinforcement. In this manner, the vehicle seal is easier to process, dispose of and recycle. A method is also disclosed for making the seal.

Abstract: An extruded strand-shaped flexible profile includes a plurality of first elements including a first extrudable plastic having a first deformability, a first flexibility and a first hardness, and a plurality of second elements including a second extrudable plastic having a second deformability, a second flexibility and a second hardness. Each of the first and second elements are arranged alternatingly one after the other in a lengthwise direction of the strand. The first deformability is greater than the second deformability, the first flexibility is greater than the second flexibility, and the second hardness is greater than the first hardness. In addition, a method for producing a strand-shaped flexible profile includes extruding at a first extrudable plastic and a second extrudable plastic alternatingly one after the other in a lengthwise direction.

Abstract: The invention relates to a strand-form vehicle seal, which is equipped with a flexible reinforcement with U- or C-form cross section, or one derived therefrom, as well as method and devices for its production. The vehicle seal according to the invention with a flexible strand-form reinforcement is distinguished thereby that the reinforcement forms a strand of at least two different substances, which is comprised of individual sections of a nonmetallic, soft-elastic material together with individual sections of another nonmetallic, however dimensionally stable and rigid material, with the individual sections in the reinforcement being disposed intermittently each alternating one after the other.

Abstract: The invention relates to devices for sealing an annular gap between two sealing surfaces of machine parts with the aid of a ring which is in contact on these two sealing surfaces, in particular on extrusion machines, where this sealing is of significance in strainer—and tool-changing devices. It is the task of the invention to create compact very simple constructed sealings built with simple means, which seals operate faultlessly even at very high pressures and yet can be relieved if a machine part is to be displaced against the other.