Patents by Inventor Frank Roerink

Frank Roerink has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PCV-2 vaccine
    Patent number: 8008001
    Abstract: The present invention relates to a vaccine and a method for protecting piglets against PCV-2 infection by administering a vaccine comprising at least 20 micrograms/dose of ORF-2 protein of porcine circovirus type 2, even when they have a relatively high titer of maternally derived antibodies against PCV-2. A vaccine according to the invention may contain a recombinant ORF-2 protein, wherein said recombinant protein is preferably produced by way of expression from a baculovirus expression vector in insect cells, said baculovirus expression vector containing the PCV-2 ORF-2 gene sequence under control of a suitable promoter.
    Type: Grant
    Filed: December 11, 2009
    Date of Patent: August 30, 2011
    Assignee: Intervet International B.V.
    Inventors: Frank Roerink, Peter Van Woensel
  • ANALYTICAL METHOD TO MONITOR VACCINE POTENCY AND STABILITY
    Publication number: 20110091984
    Abstract: The present invention is directed to methods of evaluating whether an antigen or vaccine has degraded over time using liquid chromatography. The methods described herein also relate to using liquid chromatography to evaluate the relative potency of a given antigen or vaccine.
    Type: Application
    Filed: May 21, 2009
    Publication date: April 21, 2011
    Inventors: Mark D. Williams, James Slightom, Frank Roerink
  • PCV-2 VACCINE
    Publication number: 20110064765
    Abstract: The present invention relates to a vaccine against porcine circovirus type 2 (PCV-)2 and a method for the manufacture of such a vaccine, for protecting piglets against PCV-2 infection. It has been found that a vaccine comprising at least 20 microgram/dose of ORF-2 protein of porcine circovirus type 2 (PCV-2 is capable of eliciting a protective immune response against PCV-2 (and thus against PMWS) even when they have a relatively high titer of MDA against PCV-2. A vaccine according to the invention may contain a recombinant ORF-2 protein, wherein said recombinant protein is preferably produced by way of expression from a baculovirus expression vector in insect cells, said baculovirus expression vector containing the PCV-2 ORF-2 gene sequence under control of a suitable promoter.
    Type: Application
    Filed: December 11, 2009
    Publication date: March 17, 2011
    Inventors: Frank Roerink, Peter Van Woensel
  • Pcv-2 Vaccine
    Publication number: 20080248061
    Abstract: The present invention relates to a vaccine against porcine circovirus type 2 (PCV-)2 and a method for the manufacture of such a vaccine, for protecting piglets against PCV-2 infection. It has been found that a vaccine comprising at least 20 microgram/dose of ORF-2 protein of porcine circovirus type 2 (PCV-2 is capable of eliciting a protective immune response against PCV-2 (and thus against PMWS) even when they have a relatively high titer of MDA against PCV-2. A vaccine according to the invention may contain a recombinant ORF-2 protein, wherein said recombinant protein is preferably produced by way of expression from a baculovirus expression vector in insect cells, said baculovirus expression vector containing the PCV-2 ORF-2 gene sequence under control of a suitable promoter.
    Type: Application
    Filed: September 8, 2006
    Publication date: October 9, 2008
    Applicant: Intervet International B.V.
    Inventors: Frank Roerink, Peter van Woensel