Patents by Inventor Frank Runge

Frank Runge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12115157
    Abstract: The invention relates to 3-phenoxyazetidin-1-yl-heteroaryl pyrrolidine derivatives of general formula (I) which are agonists of GPR52, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to the 3-phenoxyazetidin-1-yl-heteroaryl pyrrolidine derivatives of general formula (I) for use as a medicament, pharmaceutical compositions comprising at least a compound of general formula (I) and processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.
    Type: Grant
    Filed: September 9, 2022
    Date of Patent: October 15, 2024
    Assignees: Boehringer Ingelheim International GmbH, Arena Pharmaceuticals, Inc.
    Inventors: Kai Gerlach, Daniela Gavina Berta, Marco Ferrara, Kirsten Gutsche, Ursula Mueller-Vieira, Scott Hobson, Frank Runge, Graeme Semple, Viktor Vintonyak, Yifeng Xiong
  • Patent number: 11780827
    Abstract: The invention relates to substituted 3-phenoxyazetidin-1-yl-pyrazines of general formula (I) which are agonists of GPR52, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to the 3-phenoxyazetidin-1-yl-pyrazines of general formula (I) for use as a medicament, pharmaceutical compositions comprising the 3-phenoxyazetidin-1-yl-pyrazines of general formula (I) and processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.
    Type: Grant
    Filed: March 29, 2021
    Date of Patent: October 10, 2023
    Assignees: Boehringer Ingelheim International GmbH, Arena Pharmaceuticals, Inc.
    Inventors: Kai Gerlach, Graeme Semple, Yifeng Xiong, Barbara Bertani, Marco Ferrara, Giacomo Fossati, Scott Hobson, Uta Friederike Lessel, Frank Runge, Ursula Mueller-Vieira, Julian Wippich
  • Publication number: 20230131465
    Abstract: The invention relates to 3-phenoxyazetidin-1-yl-heteroaryl pyrrolidine derivatives of general formula (I) which are agonists of GPR52, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to the 3-phenoxyazetidin-1-yl-heteroaryl pyrrolidine derivatives of general formula (I) for use as a medicament, pharmaceutical compositions comprising at least a compound of general formula (I) and processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.
    Type: Application
    Filed: September 9, 2022
    Publication date: April 27, 2023
    Applicants: Boehringer Ingelheim International GmbH, Arena Pharmaceuticals, Inc.
    Inventors: Kai Gerlach, Daniela Gavina Berta, Marco Ferrara, Kirsten Gutsche, Ursula Mueller-Vieira, Scott Hobson, Frank Runge, Graeme Semple, Viktor Vintonyak, Yifeng Xiong
  • Publication number: 20220356172
    Abstract: The invention relates to substituted 3-phenoxyazetidin-1-yl-pyrazines of general formula (I) which are agonists of GPR52, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to the 3-phenoxyazetidin-1-yl-pyrazines of general formula (I) for use as a medicament, pharmaceutical compositions comprising the 3-phenoxyazetidin-1-yl-pyrazines of general formula (I) and processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.
    Type: Application
    Filed: March 29, 2021
    Publication date: November 10, 2022
    Applicants: Boehringer Ingelheim International GmbH, Arena Pharmaceuticals, Inc.
    Inventors: Kai Gerlach, Graeme Semple, Yifeng Xiong, Barbara Bertani, Marco Ferrara, Giacomo Fossati, Scott Hobson, Uta Friederike Lessel, Frank Runge, Ursula Mueller-Vieira, Julian Wippich
  • Publication number: 20160213000
    Abstract: Methods for controlling weeds in sugar cane plantations, wherein at least one herbicide (A) is applied as solid agrochemical formulation (B) to the plantation; and solid agrochemical formulations (B), which are dry, ready for use granules, comprising at least one herbicide (A) selected from metribuzin, diuron, bentazone, hexazinone, tebuthiuron, sulfentrazone, imazapic, imazapyr, glyphosate, MSMA, ametryn, clomazone, isoxaflutole, mesotrione, amicarbazone, atrazine, paraquat, 2,4-D, pendimethalin, saflufenacil and 1,5-dimethyl-6-thioxo-3-(2,2,7-trifluoro-3-oxo-4-(prop-2-ynyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-1,3,5-triazinane-2,4-dione (CAS 1258836-72-4) and at least one carrier (C) selected from the groups (C1) to (C7): (C1) organic based materials (botanicals); (C2) fertilizers; (C3) clays; (C4) carbonates; (C5) sulfates; (C6) synthetic of synthetically modified minerals; (C7) synthetic polymers, polymer dispersions and superabsorbent polymers.
    Type: Application
    Filed: September 23, 2014
    Publication date: July 28, 2016
    Inventors: Mariano Ignacio ETCHEVERRY, Frank RUNGE, Paulo Cesar QUEIROZ, Lucelena Patricio CARDOSO, Jamil CONSTANTIN, Gilberto VELHO, Lucio de Paula COLLETTE, Fredy MARISCAL
  • Publication number: 20090047355
    Abstract: A process for the production of pulverulent phytosterol formulations, includes preparing an aqueous solution, suspension or dispersion of the phytosterol in an aqueous molecular dispersion or colloidal dispersion of a protective colloid and drying.
    Type: Application
    Filed: October 23, 2008
    Publication date: February 19, 2009
    Applicant: BASF Aktiengesellschaft
    Inventors: Helmut Auweter, Heribert Bohn, Oliver Hasselwander, Frank Runge
  • Patent number: 7105176
    Abstract: A process is described for producing solid preparations of at least one water-soluble, sparingly water-soluble or water-insoluble active compound suitable for the food and animal feed sectors or for pharmaceutical and cosmetic applications. In addition, the invention relates to oily suspensions in which these preparations are present as disperse phase, and to the use of these preparations as additive to animal feeds, foods, pharmaceuticals and cosmetic preparations.
    Type: Grant
    Filed: November 19, 2001
    Date of Patent: September 12, 2006
    Assignee: BASF Aktiengesellschaft
    Inventors: Helmut Auweter, Heribert Bohn, Erik Lüddecke, Willy Hinz, Frank Runge, Angelika-Maria Pfeiffer
  • Patent number: 7070812
    Abstract: The invention relates to a process for producing dry powders of one or more carotenoids by a) dispersing one or more carotenoids in an aqueous molecular or colloidal solution of a mixture of lactose and a protective colloid and b) converting the dispersion which has formed into a dry powder by removing the water and, where appropriate, additionally used solvents and drying, where appropriate in the presence of a coating material, wherein at least one soybean protein is used as protective colloid in process step a).
    Type: Grant
    Filed: January 29, 2002
    Date of Patent: July 4, 2006
    Assignee: BASF Aktiengesellschaft
    Inventors: Frank Runge, Erik Lüddecke, Angelika-Maria Pfeiffer
  • Patent number: 7056525
    Abstract: Carotenoid formulations comprising a mixture of ?-carotene, lycopene and lutein, and the use thereof in human and animal foods, cosmetics and pharmaceuticals.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: June 6, 2006
    Assignee: BASF Aktiengesellschaft
    Inventors: Frank Runge, Jan Holm-Hansen, Birgit Michelsen
  • Patent number: 7037708
    Abstract: Dry microorganism cultures comprising at least one microorganism species in carrier-bound form are present in the form of particles which a) have a particle size of at least about 0.1 mm and b) are compressed; processes for preparing dry microorganism cultures and their use for preparing foodstuffs and feedstuffs are also claimed.
    Type: Grant
    Filed: April 29, 1999
    Date of Patent: May 2, 2006
    Assignee: BASF Aktiengesellschaft
    Inventors: Frank Runge, Bryan Cooper, Ulrich Bröckel, Robert Heinz, Hans-Peter Harz, Ulrich Eidelsburger, Bruno Käsler, Thomas Keller
  • Publication number: 20060035871
    Abstract: A pulverulent phytosterol formulation comprising at least one phytosterol having a mean particle size ranging from 0.01 to 100 ?m, a process for producing the pulverulent phytosterol formulation, and a food supplement, an animal feed, food or pharmaceutical or cosmetic preparation comprising the phytosterol formulation.
    Type: Application
    Filed: November 11, 2003
    Publication date: February 16, 2006
    Applicant: BASF Aktiengesellschaft
    Inventors: Helmut Auweter, Heribert Bohn, Oliver Hasselwander, Frank Runge
  • Publication number: 20040241285
    Abstract: A description is given of oily suspensions of at least one water-soluble enzyme and of a process for preparing these suspensions and of their use as additive to animal feeds.
    Type: Application
    Filed: March 24, 2004
    Publication date: December 2, 2004
    Inventors: Andreas Habich, Frank Runge, Jorg Braun, Preben Soerensen, Wolfgang Heinzl
  • Patent number: 6639113
    Abstract: A process is described for preparing dry powders of one or more oxygenated carotenoids by a) dispersing one or more oxygenated carotenoids in an aqueous molecular dispersion or colloidal dispersion of a protecting colloid and b) converting the dispersion formed into a dry powder by removing the water and any solvents additionally used and drying, in the presence or absence of a coating material, which comprises using as protecting colloid in process step a) at least one partially hydrolyzed soybean protein having a degree of hydrolysis greater than 5%.
    Type: Grant
    Filed: December 17, 2001
    Date of Patent: October 28, 2003
    Assignee: BASF Aktiengesellschaft
    Inventors: Frank Runge, Erik Lüddecke, Helmut Auweter, Angelika-Maria Pfeiffer, Willy Hinz
  • Publication number: 20030185877
    Abstract: The invention relates to a method of producing oily suspensions of water-soluble vitamins which comprises
    Type: Application
    Filed: November 18, 2002
    Publication date: October 2, 2003
    Inventors: Roland Betz, Wolfgang Bewert, Andreas Ernst, Bruno Kasler, Angelika-Maria Pfieffer, Frank Runge, Joachim U Schneider, Michael Stang
  • Publication number: 20030031706
    Abstract: Carotenoid formulations comprising a mixture of &bgr;-carotene, lycopene and lutein, and the use thereof in human and animal foods, cosmetics and pharmaceuticals.
    Type: Application
    Filed: September 5, 2002
    Publication date: February 13, 2003
    Inventors: Frank Runge, Jan Holm-Hansen, Birgit Michelsen
  • Patent number: 6509029
    Abstract: Carotenoid formulations comprising a mixture of &bgr;-carotene, lycopene and lutein, and the use thereof in human and animal foods, cosmetics and pharmaceuticals.
    Type: Grant
    Filed: March 20, 2001
    Date of Patent: January 21, 2003
    Assignee: BASF Aktiengesellschaft
    Inventors: Frank Runge, Jan Holm-Hansen, Birgit Michelsen
  • Publication number: 20020165285
    Abstract: A process is described for preparing dry powders of one or more oxygenated carotenoids by
    Type: Application
    Filed: December 17, 2001
    Publication date: November 7, 2002
    Inventors: Frank Runge, Erik Luddecke, Helmut Auweter, Angelika-Maria Pfeiffer, Willy Hinz
  • Patent number: 6458745
    Abstract: A solid crop protection composition consisting essentially of a) one or more predominantly amorphous crop protection active ingredients which are solid per se and have solubility in water of less than 500 mg/l at 25° C. and b) a coating enclosing component (a).
    Type: Grant
    Filed: April 9, 1999
    Date of Patent: October 1, 2002
    Assignee: BASF Aktiengesellschaft
    Inventors: Frank Runge, Georg Konrad Zwissler, Dieter Horn, Lutz End, Reiner Kober, Karl-Heinrich Schneider, Reinhold Stadler, Hans Ziegler, Wilhelm Rademacher, Oskar Schmidt, Volker Harries, Reinhold Saur
  • Publication number: 20020128325
    Abstract: The invention relates to a process for producing dry powders of one or more carotenoids by
    Type: Application
    Filed: January 29, 2002
    Publication date: September 12, 2002
    Inventors: Frank Runge, Erik Luddecke, Angelika-Maria Pfeiffer
  • Publication number: 20020110599
    Abstract: A process is described for producing solid preparations of at least one water-soluble, sparingly water-soluble or water-insoluble active compound suitable for the food and animal feed sectors or for pharmaceutical and cosmetic applications. In addition, the invention relates to oily suspensions in which these preparations are present as disperse phase, and to the use of these preparations as additive to animal feeds, foods, pharmaceuticals and cosmetic preparations.
    Type: Application
    Filed: November 19, 2001
    Publication date: August 15, 2002
    Inventors: Helmut Auweter, Heribert Bohn, Erik Luddecke, Willy Hinz, Frank Runge, Angelika-Maria Pfeiffer