Abstract: Filaments that contain a filament-forming material and an additive, nonwoven webs, and methods for making such filaments are provided.

Abstract: A method for delivering one or more oral care active agents to a mammal's mouth using a nonwoven web of filaments and/or fibers containing one or more oral care active agents that are releasable from the filaments and/or fibers is provided.

Abstract: This disclosure relates generally to medical devices, systems, and methods for activation of a photoactive agent during a medical procedure. In an aspect, a catheter system for activation of a photoactive agent may comprise a catheter comprising an elongate shaft comprising a proximal portion, a distal portion, and a first lumen extending along the elongate shaft. A first flexible circuit may be disposed about the distal portion of the elongate shaft. A plurality of first light-emitting diodes (LEDs) may be disposed along the first flexible circuit. A second flexible circuit may be disposed about the distal portion of the elongate shaft. A plurality of second LEDs may be disposed along the second flexible circuit. A control unit may be coupled to the proximal end of the elongate shaft. The communications cable may be disposed within the catheter and may electrically couple the first LEDs with the control unit.

Abstract: Some aspects of the present disclosure pertain to spherical devices that comprise a wire having a memorized shape comprising a spherical outer wire layer and a spherical inner wire layer disposed within the spherical outer wire layer. Other aspects of the disclosure pertain to methods of forming such devices, mandrels for forming such devices, and methods of using such devices.

Abstract: The present disclosure relates to the field of embolic coils. More specifically, the present disclosure relates to systems and methods for actively releasing an embolic coil from a delivery device into a body lumen of a patient. Delivery systems of the present disclosure may allow an embolic coil to be advanced external to the distal end of a delivery catheter without being automatically released, thereby allowing the embolic coil to be repositioned prior to deployment.

Abstract: Occlusive plugs are provided which comprise a single elongate member that is insertable into and through a microcatheter and assumes a space-occupying shape when deployed into a vascular structure. The elongate member optionally includes one or more polymer fibers, one or more polymer sleeves to secure the polymer fibers to the elongate member, and/or a radiopaque marker band.

Abstract: A medical system may include an elongate member having a proximal end and a distal end, the elongate member being movable between a collapsed configuration and an expanded configuration, and a first therapeutic agent configured to treat a condition of the lung.

Abstract: A medical system may include an elongate member having a proximal end and a distal end, the elongate member being movable between a collapsed configuration and an expanded configuration, and a first therapeutic agent configured to treat a condition of the lung.

Abstract: Described herein are various devices, assemblies and kits for creating vascular occlusions and various methods for creating vascular occlusions using such devices, assemblies and kits.

Abstract: The present disclosure provides systems and methods for actively releasing embolic coils within a body lumen of a patient.

Abstract: Some aspects of the present disclosure pertain to spherical devices that comprise a wire having a memorized shape comprising a spherical outer wire layer and a spherical inner wire layer disposed within the spherical outer wire layer. Other aspects of the disclosure pertain to methods of forming such devices, mandrels for forming such devices, and methods of using such devices.

Abstract: Occlusive plugs are provided which comprise a single elongate member that is insertable into and through a microcatheter and assumes a space-occupying shape when deployed into a vascular structure. The elongate member optionally includes one or more polymer fibers, one or more polymer sleeves to secure the polymer fibers to the elongate member, and/or a radiopaque marker band.

Abstract: A mandrel for inserting fibers into an embolic coil is provided. The mandrel generally includes a slot for an embolic coil, an anchoring mechanism, a retaining element, and multiple castellations into which fibers can be inserted.