Patents by Inventor FRANK SCHOENEN

FRANK SCHOENEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SMALL MOLECULE INHIBITORS OF THE MITOCHONDRIAL PERMEABILITY TRANSITION PORE (mtPTP)
    Publication number: 20240067600
    Abstract: The present technology relates to compounds of any one of Formula I, II, IIa, III, IV, and/or V as described herein and their tautomers and/or pharmaceutically acceptable salts, compositions, and methods of uses thereof.
    Type: Application
    Filed: March 16, 2023
    Publication date: February 29, 2024
    Applicants: UNIVERSITY OF KANSAS, Oregon Health & Science University
    Inventors: Sudeshna ROY, Paolo BERNARDI, Michael FORTE, Frank SCHOENEN, Justina SILEIKYTE
  • SMALL MOLECULE INHIBITORS OF THE MITOCHONDRIAL PERMEABILITY TRANSITION PORE (mtPTP)
    Publication number: 20220396547
    Abstract: The present technology relates to compounds of any one of Formula I, II, IIa, III, IV, and/or V as described herein and their tautomers and/or pharmaceutically acceptable salts, compositions, and methods of uses thereof.
    Type: Application
    Filed: December 14, 2020
    Publication date: December 15, 2022
    Inventors: Sudeshna ROY, Paolo BERNARDI, Michael FORTE, Frank SCHOENEN, Justina SILEIKYTE
  • BIOMARKERS PREDICTIVE OF CANCER CELL RESPONSE TO ML329 OR A DERIVATIVE THEREOF
    Publication number: 20220128562
    Abstract: The present invention is based in part on the identification of biomarkers, including NQO1, NRF2 and KEAP1, predictive of cancer cell responsiveness to treatment with ML 329 or a derivative thereof.
    Type: Application
    Filed: November 25, 2019
    Publication date: April 28, 2022
    Inventors: Rizwan Haq, David Fisher, Frank Schoenen
  • Small molecule inhibitors of the mitochondrial permeability transition pore (mtPTP)
    Patent number: 10865181
    Abstract: The present technology relates to compounds of any one of Formula I, II, IIa, III, IV, and/or V as described herein and their tautomers and/or pharmaceutically acceptable salts, compositions, and methods of uses thereof.
    Type: Grant
    Filed: November 4, 2015
    Date of Patent: December 15, 2020
    Assignees: UNIVERSITY OF KANSAS, Oregon Health & Science University
    Inventors: Sudeshna Roy, Paolo Bernardi, Michael Forte, Frank Schoenen, Justina Sileikyte
  • SMALL MOLECULE INHIBITORS OF THE MITOCHONDRIAL PERMEABILITY TRANSITION PORE (mtPTP)
    Publication number: 20180282264
    Abstract: The present technology relates to compounds of any one of Formula I, II, IIa, III, IV, and/or V as described herein and their tautomers and/or pharmaceutically acceptable salts, compositions, and methods of uses thereof.
    Type: Application
    Filed: November 4, 2015
    Publication date: October 4, 2018
    Inventors: Sudeshna ROY, Paolo BERNARDI, Michael FORTE, Frank SCHOENEN, Justina SILEIKYTE
  • LM-antibodies, functional fragments, LM-1 target antigen, and methods for making and using same
    Patent number: 9783599
    Abstract: The invention provides LM-1 antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions. The invention also provides antibodies, functional fragments, modified and variant forms that bind to LM-1 antigen (e.g., NONO/nmt55). Antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions are useful in treatment and diagnostic methods. One method includes treating metastasis of a neoplasia, tumor or cancer in a subject in need of treatment by administering to the subject an amount of a LM-1 antibody, an antibody that binds to LM-1 antigen, or a functional fragment thereof, effective to treat metastasis of the neoplasia, tumor or cancer in the subject.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: October 10, 2017
    Assignee: Patrys Limited
    Inventors: Heinz Peter Vollmers, Stephanie Ute Brandlein, Andreas Thalheimer, Leodevico L. Ilag, Barbara E. Power, Lishanthi Udabage, Frank Hensel, Frank Schoenen, Arndt-Rene Kelter, Christopher Garth Hosking
  • Ethoxyphenyl thienyl compounds and methods for the treatment of bacterial infections
    Patent number: 9688653
    Abstract: This invention relates generally to the discovery of a method of inhibiting, preventing or treating bacterial infections. The invention also relates to a method of inhibiting bacterial capsule biogenesis.
    Type: Grant
    Filed: October 15, 2014
    Date of Patent: June 27, 2017
    Assignees: Duke University, University of Kansas, Southern Research Institute
    Inventors: Patrick C. Seed, Carlos C. Goller, Steven Rogers, Brooks Maki, Frank Schoenen, James Noah, E. Lucile White
  • Methods for the treatment of bacterial infections
    Patent number: 9593095
    Abstract: This invention relates generally to the discovery of a method of inhibiting, preventing or treating bacterial infections. The invention also relates to a method of inhibiting bacterial capsule biogenesis.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: March 14, 2017
    Assignees: Duke University, University of Kansas, Southern Research Institute
    Inventors: Patrick C. Seed, Carlos C. Goller, Steven Rogers, Brooks Maki, Frank Schoenen, James Noah, E. Lucile White
  • LM-Antibodies, Functional Fragments, LM-1 Target Antigen, and Methods for Making and Using Same
    Publication number: 20150071931
    Abstract: The invention provides LM-1 antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions. The invention also provides antibodies, functional fragments, modified and variant forms that bind to LM-1 antigen (e.g., NONO/nmt55). Antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions are useful in treatment and diagnostic methods. One method includes treating metastasis of a neoplasia, tumor or cancer in a subject in need of treatment by administering to the subject an amount of a LM-1 antibody, an antibody that binds to LM-1 antigen, or a functional fragment thereof, effective to treat metastasis of the neoplasia, tumor or cancer in the subject.
    Type: Application
    Filed: March 14, 2014
    Publication date: March 12, 2015
    Applicant: Patrys Limited
    Inventors: Heinz Peter Vollmers, Stephanie Ute Brandlein, Andreas Thalheimer, Leodevico L. Ilag, Barbara E. Power, Lishanthi Udabage, Frank Hensel, Frank Schoenen, Arndt-Rene Kelter, Christopher Garth Hosking
  • ETHOXYPHENYL THIENYL COMPOUNDS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS
    Publication number: 20150031658
    Abstract: This invention relates generally to the discovery of a method of inhibiting, preventing or treating bacterial infections. The invention also relates to a method of inhibiting bacterial capsule biogenesis.
    Type: Application
    Filed: October 15, 2014
    Publication date: January 29, 2015
    Inventors: Patrick C. Seed, Carlos C. Goller, Apurba Dutta, Brooks Maki, Frank Schoenen, James Noah, Lucile White
  • METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS
    Publication number: 20140371194
    Abstract: This invention relates generally to the discovery of a method of inhibiting, preventing or treating bacterial infections. The invention also relates to a method of inhibiting bacterial capsule biogenesis.
    Type: Application
    Filed: June 16, 2014
    Publication date: December 18, 2014
    Inventors: Patrick C. Seed, Carlos C. Goller, Apurba Dutta, Brooks Maki, Frank Schoenen, James Noah, Lucile White
  • LM-1 ANTIBODIES, FUNCTIONAL FRAGMENTS, LM-1 TARGET ANTIGEN, AND METHODS FOR MAKING AND USING SAME
    Publication number: 20100322936
    Abstract: The invention provides LM-1 antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions. The invention also provides antibodies, functional fragments, modified and variant forms that bind to LM-1 antigen (e.g., NONO/nmt55). Antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions are useful in treatment and diagnostic methods. One method includes treating metastasis of a neoplasia, tumor or cancer in a subject in need of treatment by administering to the subject an amount of a LM-1 antibody, an antibody that binds to LM-1 antigen, or a functional fragment thereof, effective to treat metastasis of the neoplasia, tumor or cancer in the subject.
    Type: Application
    Filed: June 15, 2009
    Publication date: December 23, 2010
    Applicant: PATRYS LIMITED
    Inventors: HEINZ PETER VOLLMERS, STEPHANIE UTE BRANDLEIN, ANDREAS THALHEIMER, LEODEVICO L. ILAG, BARBARA E. POWER, LISHANTHI UDABAGE, FRANK HENSEL, FRANK SCHOENEN, ARNDT-RENE KELTER, CHRISTOPHER GARTH HOSKING