Abstract: Biological cells in a liquid suspension are counted in an automated cell counter that focuses an image of the suspension on a digital imaging sensor that contains at least 4,000,000 pixels each having an area of 2×2 ?m or less and that images a field of view of at least 3 mm2. The sensor enables the counter to compress the optical components into an optical path of less than 20 cm in height when arranged vertically with no changes in direction of the optical path as a whole, and the entire instrument has a footprint of less than 300 cm2. Activation of the light source, automated focusing of the sensor image, and digital cell counting are all initiated by the simple insertion of the sample holder into the instrument. The suspension is placed in a sample chamber in the form of a slide that is shaped to ensure proper orientation of the slide in the cell counter.

Abstract: Biological cells in a liquid suspension are counted in an automated cell counter that focuses an image of the suspension on a digital imaging sensor that contains at least 4,000000 pixels each having an area of 2×2 ?m or less and that images a field of view of at least 3 mm2. The sensor enables the counter to compress the optical components into an optical path of less than 20 cm in height when arranged vertically with no changes in direction of the optical path as a whole, and the entire instrument has a footprint of less than 300 cm2. Activation of the light source, automated focusing of the sensor image, and digital cell counting are all initiated by the simple insertion of the sample holder into the instrument. The suspension is placed in a sample chamber in the form of a slide that is shaped to ensure proper orientation of the slide in the cell counter.

Abstract: Biological cells in a liquid suspension are counted in an automated cell counter that focuses an image of the suspension on a digital imaging sensor that contains at least 4,000,000 pixels each having an area of 2×2 ?m or less and that images a field of view of at least 3 mm2. The sensor enables the counter to compress the optical components into an optical path of less than 20 cm in height when arranged vertically with no changes in direction of the optical path as a whole, and the entire instrument has a footprint of less than 300 cm2. Activation of the light source, automated focusing of the sensor image, and digital cell counting are all initiated by the simple insertion of the sample holder into the instrument. The suspension is placed in a sample chamber in the form of a slide that is shaped to ensure proper orientation of the slide in the cell counter.

Abstract: Biological cells in a liquid suspension are counted in an automated cell counter that focuses an image of the suspension on a digital imaging sensor that contains at least 4,000,000 pixels each having an area of 2×2 ?m or less and that images a field of view of at least 3 mm2. The sensor enables the counter to compress the optical components into an optical path of less than 20 cm in height when arranged vertically with no changes in direction of the optical path as a whole, and the entire instrument has a footprint of less than 300 cm2. Activation of the light source, automated focusing of the sensor image, and digital cell counting are all initiated by the simple insertion of the sample holder into the instrument. The suspension is placed in a sample chamber in the form of a slide that is shaped to ensure proper orientation of the slide in the cell counter.

Abstract: The present invention provides a cooling apparatus, system, and associated method. The cooling apparatus includes an insulating material, and a heat transfer device at least partially embedded within the structure material. The cooling apparatus also includes a diamond composite sheet positioned adjacent to the structure material, wherein the diamond composite sheet is in thermal communication with the heat transfer device.

Abstract: An improved optical isolator having a pre-aligned first and second collimator and a pre-aligned core assembly joined with the first collimator, the first and second collimators and core assembly all disposed within a housing tube. The core assembly is aligned with and joined directly to the first collimator and fits snugly within the housing tube. The second collimator fits within the housing tube such that it can be aligned with core assembly to minimize insertion loss. The first and second collimators are connected to the housing tube by solder joints, at least one of which is made from a low temperature solder. The core assembly includes a cylindrical permanent magnet, a pair of birefringent wedges and an optical rotator. The optical rotator is joined to a wedge on either side and the combined structure is affixed to the cylindrical permanent magnet.

Abstract: An improved optical isolator having a pre-aligned first and second collimator and a pre-aligned core assembly joined with the first collimator, the first and second collimators and core assembly all disposed within a housing tube. The core assembly is aligned with and joined directly to the first collimator and fits snugly within the housing tube. The second collimator fits within the housing tube such that it can be aligned with core assembly to minimize insertion loss. The first and second collimators are connected to the housing tube by solder joints, at least one of which is made from a low temperature solder. The core assembly includes a cylindrical permanent magnet, a pair of birefringent wedges and an optical rotator. The optical rotator is joined to a wedge on either side and the combined structure is affixed to the cylindrical permanent magnet.

Abstract: The invention provides methods of using two-dimensional nuclear magnetic resonance to identify compounds that bind to a target compound.