Abstract: The present invention relates to oxazolidin-2-one substituted pyrimidine compounds that act as PI3K (phosphatidylinositol-3-kinase) inhibitors, as well as pharmaceutical compositions thereof, methods for their manufacture and uses for the treatment of conditions, diseases and disorders dependent on PI3K.

Abstract: The present invention relates to oxazolidin-2-one substituted pyrimidine compounds that act as PI3K (phosphatidylinositol-3-kinase) inhibitors, as well as pharmaceutical compositions thereof, methods for their manufacture and uses for the treatment of conditions, diseases and disorders dependent on PI3K.

Abstract: The invention relates to the use of 1H-imidazo[4,5-c]quinolinone derivatives and salts thereof in the treatment of protein and/or lipid kinase dependent diseases and for the manufacture of pharmaceutical preparations for the treatment of said diseases; 1H-imidazo[4,5-c]quinolinone derivatives for use in the treatment of protein and/or lipid kinase dependent diseases; a method of treatment against said diseases, comprising administering the 1H-imidazo[4,5-c]quinolinone derivatives to a warm-blooded animal, especially a human; pharmaceutical preparations comprising an 1H-imidazo[4,5-c]quinolinone derivative, especially for the treatment of a protein and/or lipid kinase dependent disease; novel 1H-imidazo[4,5-c]quinolinone derivatives; and a process for the preparation of the novel 1H-imidazo[4,5-c]quinolinone derivatives.

Abstract: The invention relates to the use of 1H-imidazo[4,5-c]quinolinone derivatives and salts thereof in the treatment of protein and/or lipid kinase dependent diseases and for the manufacture of pharmaceutical preparations for the treatment of said diseases; 1H-imidazo[4,5-c]quinolinone derivatives for use in the treatment of protein and/or lipid kinase dependent diseases; a method of treatment against said diseases, comprising administering the 1H-imidazo[4,5-c]quinolinone derivatives to a warm-blooded animal, especially a human; pharmaceutical preparations comprising an 1H-imidazo[4,5-c]quinolinone derivative, especially for the treatment of a protein and/or lipid kinase dependent disease; novel 1H-imidazo[4,5-c]quinolinone derivatives; and a process for the preparation of the novel 1H-imidazo[4,5-c]quinolinone derivatives.

Abstract: A user manipulated apparatus for producing straight construction lines on sheet material includes a linearly extensive frame with integrally formed handle and an expendable marking strip affixed to a bottom edge of the frame. A user positions the frame so that its ends are in registry with the endpoints of a desired construction line, with the marking strip contacting the surface of the sheet material. The user then linearly displaces the frame a short distance along its length so that the marking strip rubs along the surface of the sheet material and produces a visible construction line. The portion of the frame that supports the marking substance may be compliant to ensure that the marking substance fully engages the surface of the sheet material even when the sheet material has surface irregularities or is not perfectly planar.

Abstract: The invention relates to the use of 1H-imidazo[4,5-c]quinolinone derivatives and salts thereof in the treatment of protein and/or lipid kinase dependent diseases and for the manufacture of pharmaceutical preparations for the treatment of said diseases; 1H-imidazo[4,5-c]quinolinone derivatives for use in the treatment of protein and/or lipid kinase dependent diseases; a method of treatment against said diseases, comprising administering the 1H-imidazo[4,5-c]quinolinone derivatives to a warm-blooded animal, especially a human; pharmaceutical preparations comprising an 1H-imidazo[4,5-c]quinolinone derivative, especially for the treatment of a protein and/or lipid kinase dependent disease; novel 1H-imidazo[4,5-c]quinolinone derivatives; and a process for the preparation of the novel 1H-imidazo[4,5-c]quinolinone derivatives.

Abstract: A business object model, which reflects data that is used during a given business transaction, is utilized to generate interfaces. This business object model facilitates commercial transactions by providing consistent interfaces that are suitable for use across industries, across businesses, and across different departments within a business during a business transaction. In some operations, software creates, updates, or otherwise processes information related to an analytical view of trading order, a trade price specification contract, and/or a trading order business object.

Abstract: A dual mode carpet cleaning method is capable of being used in both a deep cleaning mode and a fast drying surface cleaning mode. The method utilizes a carpet cleaning apparatus that provides selective communication with different sets of cleaning jets. One set of cleaning jets is operated to deliver a first cleaning solution that penetrates deeply into a carpet in the deep cleaning mode. A second set of cleaning jets is operated to deliver a lower flow rate of a second cleaning solution that does not penetrate as deeply into the carpet and dries quickly. The method involves manually operating a valve on the apparatus to selectively communicate a source of cleaning fluid of the apparatus with one of the first set of cleaning jets and the second set of cleaning jets, and discharging the cleaning liquid from the selected one of the first set of cleaning jets and second set of cleaning jets onto a carpet to be cleaned.

Abstract: Systems and methods are provided for configuring and executing complex software. The complex software may include code corresponding to a core layer and code corresponding to at least one of a plurality of industry extensions. A method for configuring software is provided that includes presenting at least one business set for selection by the user. The method further includes receiving a selection of at least one business set from the user, and receiving a selection of functions from the user based on the selected business set. The method further includes determining whether the selection of functions by the user is valid, and activating switches to enable software elements corresponding to the selected functions, if the user selection of the functions is determined to be valid.

Abstract: Systems and methods are provided for configuring and executing complex software. The complex software may include code corresponding to a core layer and code corresponding to at least one of a plurality of industry extensions. A method for configuring software is provided that includes presenting at least one business set for selection by the user. The method further includes receiving a selection of at least one business set from the user, and receiving a selection of functions from the user based on the selected business set. The method further includes determining whether the selection of functions by the user is valid, and activating switches to enable software elements corresponding to the selected functions, if the user selection of the functions is determined to be valid.

Abstract: In a system and method for logistics management according to embodiments of the present invention, a user interface may present a user with input fields that correlate naturally with typical logistics processes. More specifically, the user interface may comprise: a step field to receive a value relating to a current step in a logistics process, and data associated therewith; a predecessor step field to receive a value relating to a step in the logistics process previous to the current step, and data associated therewith; and a mode field to receive a value relating to an action to be performed based on values received in the step and predecessor step fields. The values acceptable by the fields may be terms that are descriptive of typical activities in a particular user's business, so that using the interface has a natural or intuitive feel for the user.

Abstract: A dual mode carpet cleaning machine capable of being used in both a traditional deep cleaning mode and a fast drying surface cleaning mode. A selection mechanism provides selective communication with different sets of application jets. One set of application jets delivers a first cleaning solution that penetrates deeply into a carpet. After agitation with a scrub brush the device removes the cleaning solution and unwanted soil through a vacuum nozzle. The other set of jets delivers a lower flow rate of a second cleaning solution that does not penetrate deeply into the carpet. In addition, a novel cleaning solution is disclosed for use with the machine in differing concentrations, depending on the desired application.

Abstract: Embodiments of the present invention relate to logistics management software. The software includes a user interface configurable to receive inputs relating to logistics operations in user-defined language.

Abstract: A dual mode carpet cleaning machine capable of being used in both a traditional deep cleaning mode and a fast drying surface cleaning mode. A selection mechanism provides selective communication with different sets of application jets. One set of application jets delivers a first cleaning solution that penetrates deeply into a carpet. After agitation with a scrub brush the device removes the cleaning solution and unwanted soil through a vacuum nozzle. The other set of jets delivers a lower flow rate of a second cleaning solution that does not penetrate deeply into the carpet. In addition, a novel cleaning solution is disclosed for use with the machine in differing concentrations, depending on the desired application. The carpet cleaning solutions dry more quickly when applied to carpet than previous solutions; the combined performance of the system displays similar cleaning efficiencies to previous carpet cleaning machines but obtains significantly reduced drying times.

Abstract: A relay box having a carrier plate and a plug-in module is disclosed. A conductor to be switched is brought into electrical contact with a relay through the plug-in module and a plug contact arranged in the plug-in module. The relay is plugged both into the plug-in module and into the carrier plate of the relay box through plug contacts. Because of the modular arrangement, increased flexibility is possible when using a prefabricated carrier plate having terminal positions provided for a plurality of relays.

Abstract: Dendritic cell (DC) genes and polypeptide and their function in the identification of compounds which are (ant)agonists; and (ant)agonists to DC polypeptides.

Abstract: The invention is a cleaning tool housing assembly and a replaceable cleaning assembly. The manifold, in combination with a fluid intake element, also delivers fluid (under pressure through holes in the manifold located in a longitudinal channel) to a sponge. Two spaced apart fluid barriers are longitudinally disposed in the sponge. As fluid is introduced into the center of the sponge, between the fluid barriers, the fluid travels toward the opposite surface of the sponge. The fluid is prevented from traveling laterally due to the fluid barriers. As vacuum pressure, negative pressure, is exerted on the outer portions of the sponge (on each side of the fluid barriers), fluid is pulled back through the sponge, through the manifold and through the nozzles into the hollow housing body.

Abstract: A dual mode carpet cleaning machine capable of being used in both a traditional deep cleaning mode and a fast drying surface cleaning mode. A selection mechanism provides selective communication with different sets of application jets. One set of application jets delivers a first cleaning solution that penetrates deeply into a carpet. After agitation with a scrub brush the device removes the cleaning solution and unwanted soil through a vacuum nozzle. The other set of jets delivers a lower flow rate of a second cleaning solution that does not penetrate deeply into the carpet. In addition, a novel cleaning solution is disclosed for use with the machine in differing concentrations, depending on the desired application.

Abstract: The invention is a cleaning tool housing assembly and a replaceable cleaning assembly. The manifold, in combination with a fluid intake element, also delivers fluid (under pressure through holes in the manifold located in a longitudinal channel) to a sponge. Two spaced apart fluid barriers are longitudinally disposed in the sponge. As fluid is introduced into the center of the sponge, between the fluid barriers, the fluid travels toward the opposite surface of the sponge. The fluid is prevented from traveling laterally due to the fluid barriers. As vacuum pressure, negative pressure, is exerted on the outer portions of the sponge (on each side of the fluid barriers), fluid is pulled back through the sponge, through the manifold and through the nozzles into the hollow housing body.