Patents by Inventor Frank TOMAKA

Frank TOMAKA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combinations of Vaccines and Neutralizing Antibodies for Treating Human Immunodeficiency Virus Infection in Subjects Undergoing Antiretroviral Treatment
    Publication number: 20230000973
    Abstract: Methods for inducing an immune response against Human Immunodeficiency Virus (HIV) in HIV-infected subjects undergoing antiretroviral therapy (ART) are described. The methods involve initial administration of an adenovirus vector vaccine and subsequent administration of a poxvirus vector vaccine, followed by administration of anti-HIV broadly neutralizing antibodies (bNAb).
    Type: Application
    Filed: June 23, 2022
    Publication date: January 5, 2023
    Inventors: Dan H. Barouch, Boris D. Juelg, Maria Grazia Pau, Frank Tomaka
  • Compositions and Methods for Inducing Protective Immunity Against Human Immunodeficiency Virus Infection
    Publication number: 20220096622
    Abstract: Compositions, vaccines and methods for inducing an immunity, including a protective immunity, against Human Immunodeficiency Virus (HIV) infection are described. Heterologous vaccine combinations of one or more adenovirus 26 vectors using for priming immunization and an isolated HIV antigenic polypeptide in combination with one or more MVA vectors for boosting immunization induced strong protective immunity against infections by one or multiple clades of HIV.
    Type: Application
    Filed: December 6, 2021
    Publication date: March 31, 2022
    Inventors: Dan BAROUCH, Johanna SCHUITEMAKER, Maria Grazia PAU, Danielle VAN MANEN, Frank TOMAKA, Jennifer Anne HENDRIKS
  • Compositions and methods for inducing protective immunity against human immunodeficiency virus infection
    Patent number: 11207400
    Abstract: Compositions, vaccines and methods for inducing an immunity, including a protective immunity, against Human Immunodeficiency Virus (HIV) infection are described. Heterologous vaccine combinations of one or more adenovirus 26 vectors using for priming immunization and an isolated HIV antigenic polypeptide in combination with one or more MVA vectors for boosting immunization induced strong protective immunity against infections by one or multiple clades of HIV.
    Type: Grant
    Filed: October 4, 2019
    Date of Patent: December 28, 2021
    Assignees: Janssen Vaccines & Prevention B.V., Beth Israel Deaconess Medical Center, Inc.
    Inventors: Dan Barouch, Johanna Schuitemaker, Maria Grazia Pau, Danielle Van Manen, Frank Tomaka, Jennifer Anne Hendriks
  • COMPOSITIONS AND METHODS FOR INDUCING PROTECTIVE IMMUNITY AGAINST HUMAN IMMUNODEFICIENCY VIRUS INFECTION
    Publication number: 20200030437
    Abstract: Compositions, vaccines and methods for inducing an immunity, including a protective immunity, against Human Immunodeficiency Virus (HIV) infection are described. Heterologous vaccine combinations of one or more adenovirus 26 vectors using for priming immunization and an isolated HIV antigenic polypeptide in combination with one or more MVA vectors for boosting immunization induced strong protective immunity against infections by one or multiple clades of HIV.
    Type: Application
    Filed: October 4, 2019
    Publication date: January 30, 2020
    Inventors: Dan BAROUCH, Johanna SCHUITEMAKER, Maria Grazia PAU, Danielle VAN MANEN, Frank TOMAKA, Jennifer Anne HENDRIKS
  • Methods for inducing an immune response against human immunodeficiency virus infection in subjects undergoing antiretroviral treatment
    Patent number: 10525123
    Abstract: Methods for inducing an immune response against Human Immunodeficiency Virus (HIV) in HIV-infected subjects undergoing antiretroviral therapy (ART) are described. The methods include administering an adenovirus vector primer vaccine and a modified vaccinia virus (MVA) vector booster vaccine encoding mosaic HIV antigens.
    Type: Grant
    Filed: April 16, 2019
    Date of Patent: January 7, 2020
    Assignees: Janssen Vaccines & Prevention B.V., Beth Israel Deaconess Medical Center, Inc., THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC., The Government of The United States, as represented by The Secretary Of The Army
    Inventors: Frank Tomaka, Maria Grazia Pau, Johanna Schuitemaker, Dan Barouch, Jintanat Ananworanich, Merlin Robb, Nelson L. Michael, Jerome Kim
  • Methods for inducing protective immunity against human immunodeficiency virus infection
    Patent number: 10471137
    Abstract: Compositions, vaccines and methods for inducing protective immunity against Human Immunodeficiency Virus (HIV) infection are described. Heterologous vaccine combinations of one or more viral expression vectors and an isolated antigenic polypeptide induced strong protective immunity against infections by one or multiple clades of HIV.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: November 12, 2019
    Assignees: Janssen Vaccines & Prevention B.V., Beth Israel Deaconess Medical Center, Inc.
    Inventors: Dan Barouch, Johanna Schuitemaker, Maria Grazia Pau, Danielle Van Manen, Frank Tomaka, Jennifer Anne Hendriks
  • METHODS FOR INDUCING AN IMMUNE RESPONSE AGAINST HUMAN IMMUNODEFICIENCY VIRUS INFECTION IN SUBJECTS UNDERGOING ANTIRETROVIRAL TREATMENT
    Publication number: 20190247491
    Abstract: Methods for inducing an immune response against Human Immunodeficiency Virus (HIV) in HIV-infected subjects undergoing antiretroviral therapy (ART) are described. The methods include administering an adenovirus vector primer vaccine and a modified vaccinia virus (MVA) vector booster vaccine encoding mosaic HIV antigens.
    Type: Application
    Filed: April 16, 2019
    Publication date: August 15, 2019
    Inventors: Frank TOMAKA, Maria Grazia PAU, Johanna SCHUITEMAKER, Dan BAROUCH, Jintanat ANANWORANICH, Merlin ROBB, Nelson L. MICHAEL, Jerome KIM
  • METHODS FOR SAFE INDUCTION OF CROSS-CLADE IMMUNITY AGAINST HIV INFECTION IN HUMANS
    Publication number: 20190231866
    Abstract: Provided are means and methods for generating safe immune responses in humans against multiple clades of human immunodeficiency virus (HIV). The observed immune responses were improved over earlier reported immune responses in clinical trials.
    Type: Application
    Filed: January 24, 2019
    Publication date: August 1, 2019
    Inventors: Maria Grazia PAU, Daniel John STIEH, Frank TOMAKA, Steven NIJS
  • Methods for inducing an immune response against human immunodeficiency virus infection in subjects undergoing antiretroviral treatment
    Patent number: 10307477
    Abstract: Methods for inducing an immune response against Human Immunodeficiency Virus (HIV) in HIV-infected subjects undergoing antiretroviral therapy (ART) are described. The methods include administering an adenovirus vector primer vaccine and a modified vaccinia virus (MVA) vector booster vaccine encoding mosaic HIV antigens.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: June 4, 2019
    Assignees: Janssen Vaccines & Prevention B.V., The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Beth Israel Deaconess Medical Center, Inc., The United States of America, as represented by The Secretary Of The Army
    Inventors: Frank Tomaka, Maria Grazia Pau, Johanna Schuitemaker, Dan Barouch, Jintanat Ananworanich, Merlin Robb, Nelson L. Michael, Jerome Kim
  • METHODS FOR INDUCING AN IMMUNE RESPONSE AGAINST HUMAN IMMUNODEFICIENCY VIRUS INFECTION IN SUBJECTS UNDERGOING ANTIRETROVIRAL TREATMENT
    Publication number: 20190083620
    Abstract: Methods for inducing an immune response against Human Immunodeficiency Virus (HIV) in HIV-infected subjects undergoing antiretroviral therapy (ART) are described. The methods include administering an adenovirus vector primer vaccine and either a Modified Vaccinia Ankara virus (MVA) vector booster vaccine or adenovirus booster vaccine in combination with isolated HIV envelope polypeptides.
    Type: Application
    Filed: September 17, 2018
    Publication date: March 21, 2019
    Inventors: Maria Grazia PAU, Frank TOMAKA, Daniel John STIEH, Michal SARNECKI, Dan BAROUCH, Boris JUELG
  • METHODS FOR SAFE INDUCTION OF CROSS-CLADE IMMUNITY AGAINST HUMAN IMMUNODEFICIENCY VIRUS INFECTION IN HUMAN
    Publication number: 20190022212
    Abstract: Methods for inducing safe and effective immune response against multiple clades of Human Immunodeficiency Virus (HIV) infection in human subjects are described. The methods involve heterologous vaccine combinations of adenovirus serotype 26 expression vectors expressing at least three mosaic HIV antigens with at least one isolated HIV gp140 protein.
    Type: Application
    Filed: July 20, 2018
    Publication date: January 24, 2019
    Inventors: Dan BAROUCH, Johanna SCHUITEMAKER, Maria Grazia PAU, Danielle VAN MANEN, Frank TOMAKA, Jennifer Anne HENDRIKS
  • Methods and compositions for inducing protective immunity against human immunodeficiency virus infection
    Patent number: 10137191
    Abstract: Compositions, vaccines and methods for inducing protective immunity against Human Immunodeficiency Virus (HIV) infection are described. Heterologous vaccine combinations of one or more viral expression vectors and an isolated antigenic polypeptide induced strong protective immunity against infections by one or multiple clades of HIV.
    Type: Grant
    Filed: September 24, 2015
    Date of Patent: November 27, 2018
    Assignees: Janssen Vaccines & Prevention B.V., Beth Israel Deaconess Medical Center, Inc.
    Inventors: Dan Barouch, Johanna Schuitemaker, Maria Grazia Pau, Danielle Van Manen, Frank Tomaka, Jennifer Anne Hendriks
  • METHODS FOR INDUCING PROTECTIVE IMMUNITY AGAINST HUMAN IMMUNODEFICIENCY VIRUS INFECTION
    Publication number: 20180250385
    Abstract: Compositions, vaccines and methods for inducing protective immunity against Human Immunodeficiency Virus (HIV) infection are described. Heterologous vaccine combinations of one or more viral expression vectors and an isolated antigenic polypeptide induced strong protective immunity against infections by one or multiple clades of HIV.
    Type: Application
    Filed: May 2, 2018
    Publication date: September 6, 2018
    Inventors: Dan BAROUCH, Johanna SCHUITEMAKER, Maria Grazia PAU, Danielle VAN MANEN, Frank TOMAKA, Jennifer Anne HENDRIKS
  • METHODS FOR INDUCING AN IMMUNE RESPONSE AGAINST HUMAN IMMUNODEFICIENCY VIRUS INFECTION IN SUBJECTS UNDERGOING ANTIRETROVIRAL TREATMENT
    Publication number: 20180064803
    Abstract: Methods for inducing an immune response against Human Immunodeficiency Virus (HIV) in HIV-infected subjects undergoing antiretroviral therapy (ART) are described. The methods include administering an adenovirus vector primer vaccine and a modified vaccinia virus (MVA) vector booster vaccine encoding mosaic HIV antigens.
    Type: Application
    Filed: September 1, 2017
    Publication date: March 8, 2018
    Inventors: Frank TOMAKA, Maria Grazia PAU, Johanna SCHUITEMAKER, Dan BAROUCH, Jintanat ANANWORANICH, Merlin ROBB, Nelson L. MICHAEL, Jerome KIM
  • METHODS AND COMPOSITIONS FOR INDUCING PROTECTIVE IMMUNITY AGAINST HUMAN IMMUNODEFICIENCY VIRUS INFECTION
    Publication number: 20160089432
    Abstract: Compositions, vaccines and methods for inducing protective immunity against Human Immunodeficiency Virus (HIV) infection are described. Heterologous vaccine combinations of one or more viral expression vectors and an isolated antigenic polypeptide induced strong protective immunity against infections by one or multiple clades of HIV.
    Type: Application
    Filed: September 24, 2015
    Publication date: March 31, 2016
    Inventors: Dan BAROUCH, Johanna SCHUITEMAKER, Maria GRAZIA PAU, Danielle VAN MANEN, Frank TOMAKA, Jennifer Anne HENDRIKS