Abstract: Method for identifying compounds that interfere with or modulate sister chromatid separation in animal or plant cells by modulating a protease with separin-like cysteine endopeptidase activity. Inhibitors of separin activity are useful in cancer therapy, to prevent birth defects and to increase ploidy in plants.

Abstract: An arrangement for controlling the closing and opening operation of an aircraft passenger door includes electromechanical actuators and manual actuators for moving the door and for actuating the various latching and locking mechanisms of the door, a door control unit, as well as an actuator control unit, an operating console, and sensors that sense position and status conditions of the door, all connected to the door control unit, a power supply, and power switches connected serially between the power supply and the actuator control unit. In an operating method, the door control unit controls the actuator control unit, and can switch all of the individual function steps for opening or closing the door selectively between being manually controlled and being electromechanically controlled. While the door can be actuated electrically, in the case of a malfunction or if desired by the operator, it can be operated fully or partly mechanically under a manual control.

Abstract: An arrangement for controlling the closing and opening operation of an aircraft passenger door includes electromechanical actuators and manual actuators for moving the door and for actuating the various latching and locking mechanisms of the door, a door control unit, as well as an actuator control unit, an operating console, and sensors that sense position and status conditions of the door, all connected to the door control unit, a power supply, and power switches connected serially between the power supply and the actuator control unit. In an operating method, the door control unit controls the actuator control unit, and can switch all of the individual function steps for opening or closing the door selectively between being manually controlled and being electromechanically controlled. While the door can be actuated electrically, in the case of a malfunction or if desired by the operator, it can be operated fully or partly mechanically under a manual control.

Abstract: The invention relates to a hydrodynamic torque converter including a turbine wheel arranged inside of a housing, a torque converter lockup clutch, an axially mounted piston, a torsional vibration damper and a hub. The turbine wheel and the piston are rotationally fixed to the input component of the damper. The input component is connected to the hub by means of a connection provided with a circumferential backlash. The output component of the damper is connected to the hub without circumferential backlash.

Abstract: The invention relates to hydrodynamic torque converter (1) comprising a turbine wheel (3) arranged inside of a housing (2), a torque converter lockup clutch (10), an axially mounted piston (6), a torsional vibration damper (20) and a hub (5). The turbine wheel (3) and the piston (6) are rotationally fixed to the input component (21) of said damper (20). The input component (21) is connected to the hub (5) by means of a connection (52) provided with circumferential backlash. The output component (22) of the damper (20) is connected to the hub (5) without circumferential backlash.

Abstract: The bypass clutch in the fluid-containing housing of the hydrokinetic torque converter in the power train of a motor vehicle is provided with a first friction surface carried by a radially extending or conical section of the housing, and with a complementary friction surface carried by an axially movable piston or by an intermediate clutch plate of the bypass clutch. At least one of the friction surfaces is provided with an array of pockets and/or channels for a fluid (such as oil) which withdraws friction heat developing when the bypass clutch is partially engaged so that the friction surfaces contact but slip relative to each other. The depth and/or the width of the channels is at least substantially constant, and such channels can include bends between straight channel sections. The inlets of the channels can be located at the radially inner or radially outer marginal portion and their outlets can be located at the radially outer or inner marginal portion of the respective friction surface.