Abstract: A Targeted Advertising and Inventory Optimization Improvement system utilizing user location and selection data to generate targeted advertisements and store layout optimizations. The targeted advertising is generated based on user location and item selection data as a user navigates a store along a predetermined route.

Abstract: An Indoor location mapping and wayfinding system for mapping waypoints on an interactive mapping system that can function both indoors and outdoors based on user selections and location. It can include a shopping system that allows users to pre-select items for purchase, maps the items on an indoor map of the store, and provides a route to the user for the collection of the selected items.

Abstract: An Indoor location mapping and wayfinding system for mapping waypoints on an interactive mapping system that can function both indoors and outdoors based on user selections and location. It can include a shopping system that allows users to pre-select items for purchase, maps the items on an indoor map of the store, and provides a route to the user for the collection of the selected items.

Abstract: An Indoor location mapping and wayfinding system for mapping waypoints on an interactive mapping system that can function both indoors and outdoors based on user selections and location. It can include a shopping system that allows users to pre-select items for purchase, maps the items on an indoor map of the store, and provides a route to the user for the collection of the selected items.

Abstract: An Indoor location mapping and wayfinding system for mapping waypoints on an interactive mapping system that can function both indoors and outdoors based on user selections and location. It can include a shopping system that allows users to pre-select items for purchase, maps the items on an indoor map of the store, and provides a route to the user for the collection of the selected items.

Abstract: A folding dolly for towing a vehicle provides two rectangular wheel cradles, which secure the front wheels of the vehicle to be towed, and are joined by a cross member. A two-piece tongue extends forward from the center of the cross member. One leading corner of each wheel cradle is joined to the tongue with a diagonal steering arm. Each wheel cradle also provides a removable wheel. Most of the components of the dolly provide a telescoping feature, such that they may be collapsed into a compact length for storage, then extended to fit the vehicle to be towed, and locked into position.

Abstract: The invention provides methods and materials for use in modulating T cell activation, based on the production and secretion of soluble cytotoxic T-lymphocyte antigen-4 (sCTLA-4) by cells of the immune system. The method involves stimulating secretion of endogenous sCTLA-4 by T cells, which have preferably previously been exposed to an antigen, by exposing the said cells to a stimulatory agent, preferably a peptide which comprises at least one antigenic determinant of said antigen. The cells may also be exposed to a CD28 stimulatory binding agent, either alone or in combination with the antigenic peptide. In preferred embodiments, the method may be used for treatment or prophylaxis of a disease characterized by a pathogenic immune or autoimmune response. The invention also provides a system for inhibiting sCTLA-4 secretion by T cells.

Abstract: A base element (10) is fixedly mounted to a microscope. The upper surface (18) of an annular mounting portion (15) at the top of base element (10) is flat and forms a track which extends around the vertical centerline, i.e. the optical axis of the microscope. Movably secured to the upper surface (18) of the annular mounting portion (15) is a positioner element (28). The positioner element (28) includes a portion (46) which is movable toward and away from the centerline of the microscope (12). On the top surface of the movable portion (46) is a translator element (64) which is rotatable relative to the positioner element (28). A micromanipulator (73), which is a microscope accessory, is mountable on the translator (64). The apparatus as a whole provides a stable platform for support and movement of a plurality of micromanipulators.