Abstract: Provided herein are compounds of Formula (I), their pharmaceutically acceptable salts, and their pharmaceutical compositions: wherein R1, R2, R3a, R3b, R4, R5, and A are defined in the present disclosure. The compounds are potent inhibitors of the main protease (Mpro) of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2), and they are useful in treating or preventing COVID-19 in a subject.

Abstract: A partial beam splitter includes a substrate including a substrate material; and a coating arranged on at least one main surface of the substrate. Along a first direction which is parallel to a normal vector of the main surface, the substrate and all coatings having a total thickness. For a specific light beam having a specific wavelength within a range of 450 nm and 650 nm which is incident on the partial beam splitter along a second direction with an angle of 32° enclosed between a vector pointing in the first direction and a vector pointing in the second direction, the specific light beam after transmitting through the partial beam splitter has a phase having a phase difference of an absolute value of smaller than or equal to 30° compared to the case in which, under otherwise identical conditions, the partial beam splitter is replaced by a similar reference substrate.

Abstract: A window includes: a vitreous substrate pane forming a substrate, the substrate including at least one surface; and a coating disposed on the at least one surface of the substrate, wherein at least one of: (a) the window within a wavelength range from 400 to 700 nm has an average transmittance ?avg,400 nm to 700 nm of less than 15%, where ?avg,400 nm to 700 nm is defined as ? a ? v ? ? , 400 ? n ? m - 700 ? n ? m = ? 400 ? n ? m 700 ? n ? m ? ? d ? ? 700 ? n ? m - 400 ? n ? m ; and (b) at any wavelength the window has a spectral transmittance of less than 15%, wherein the window at at least one wavelength within a wavelength range from 875 nm to 1600 nm has a transmittance of at least 75%.

Abstract: A laminate includes at least two sheets, one of the at least two sheets including a colored glass and another of the at least two sheets being a further sheet. The sheet including the colored glass in a wavelength range from 875 nm to 1600 nm has an internal transmittance at at least one wavelength of at least 75%. A connecting layer is disposed between the at least two sheets. The laminate has a thickness of at most 6 mm. The laminate in a wavelength range from 400 to 700 nm has an average transmittance ?avg,400 nm to 700 nm of less than 15% where ?avg,400 nm to 700 nm is defined as ? a ? v ? g , 400 ? nm - 700 ? nm = ? 400 ? nm 700 ? nm ? ? d ? ? 700 ? nm - 400 ? nm and/or at each wavelength has a spectral transmittance of less than 15%.

Abstract: A glass includes: a plurality of components (in wt.-%) as follows: Component Proportion (% by weight) SiO2 50-80? Al2O3 0-10 B2O3 0-15 Li2O 0-20 Na2O 0-20 K2O 0-25 BaO 0-10 CaO 0-10 MgO 0-10 ZnO 0-10 La2O3 0-20 TiO2 0-5? Cl 0-3? MnO2 0.2-5.0? Cr2O3 0.05-3.0,? a sum of a plurality of proportions of Li2O, Na2O and K2O being in a range of from 5.0 to 30.0 wt.-%, a sum of a plurality of amounts of MnO2 and Cr2O3 being at least 0.3 wt.-%, and a ratio of a plurality of proportions of MnO2 (in wt.-%) and Cr2O3 (in wt.-%) being in a range of from 1.5:1 to 12.5:1.

Abstract: In an electromagnetic actuator having a housing, two ferromagnetic pole shoes are distanced from each other and are rigidly connected to the housing. A mobile structure, which can be moved in the housing along an axis between two end positions, is arranged between the pole shoes, includes at least one magnet system, and is connected to a shaft that is axially displaceable in the housing. The magnet system includes at least one arrangement of at least one permanent magnet polarized radially with respect to the axis, and an annular coil connectable to a current source. The magnet system forms, together with the pole shoes, an air gap system having axially variable air gaps. The mobile structure is securable in each end position without excitation of the coil and is movable from one assumed end position into the opposite end position by excitation of the coil.