Patents by Inventor Frank Zal

Frank Zal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bioreactor using oxygen-carrying molecules
    Patent number: 10119110
    Abstract: The present invention relates to devices and bioreactors capable of delivering oxygen to a cell culture using oxygen-carrying molecules. The bioreactor comprises at least two chambers separated by an oxygen-permeable membrane. The oxygen-carrying molecules are chosen from extracellular hemoglobin isolated from worm belonging to Arenicoliolae family or Nereidiolae family.
    Type: Grant
    Filed: April 21, 2010
    Date of Patent: November 6, 2018
    Assignee: HEMARINA
    Inventor: Frank Zal
  • BIOREACTOR USING OXYGEN-CARRYING MOLECULES
    Publication number: 20120040453
    Abstract: The present invention relates to devices and bioreactors capable of delivering oxygen to a cell culture using oxygen-carrying molecules. The bioreactor comprises at least two chambers separated by an oxygen-permeable membrane. The oxygen-carrying molecules are chosen from extracellular hemoglobin isolated from worm belonging to Arenicoliolae family or Nereidiolae family.
    Type: Application
    Filed: April 21, 2010
    Publication date: February 16, 2012
    Applicant: HEMARINA
    Inventor: Frank Zal
  • Method for the dissociation of the extracellular haemoglobin molecule of arenicola marina and the characterisation of the protein chains forming the molecule and the nucleotide sequences coding for said protein chains
    Publication number: 20070037160
    Abstract: The invention relates to a method of dissociating the extracellular haemoglobin molecule of annelids, e.g. Arenicola marina, which can be used to obtain the protein chains forming said molecule. The inventive method is characterised in that it comprises a step consisting in bringing an extracellular haemoglobin sample from annelids, e.g. Arenicola marina, into contact with at least one dissociating agent, e.g. a mixture containing dithiothreitol (DTT) or tris(2-carboxyethyl)phosphine (TCEP) hydrochloride or beta-mercaptoethanol and a dissociation buffer for a sufficient length of time in order to separate the protein chains from one another.
    Type: Application
    Filed: October 13, 2004
    Publication date: February 15, 2007
    Inventors: Frank Zal, Christine Chabasse, Morgane Rousselot, Xavier Bailly