Patents by Inventor Frank Zeigler

Frank Zeigler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11191780
    Abstract: The present invention is directed to methods of inhibiting cancer cell growth or proliferation by contacting the cancer cell with an extracellular matrix (ECM) composition. Also provided are methods of delivering a chemotherapeutic agent to a cancer cell by contacting a cancer cell with an extracellular matrix composition containing a chemotherapeutic agent. Also provided are compositions containing ECM and a chemotherapeutic agent.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: December 7, 2021
    Assignee: Adaptive Biologix, Inc.
    Inventors: Gail K. Naughton, Frank Zeigler, Emmett Pinney
  • Publication number: 20180117092
    Abstract: The present invention is directed to methods of inhibiting cancer cell growth or proliferation by contacting the cancer cell with an extracellular matrix (ECM) composition. Also provided are methods of delivering a chemotherapeutic agent to a cancer cell by contacting a cancer cell with an extracellular matrix composition containing a chemotherapeutic agent. Also provided are compositions containing ECM and a chemotherapeutic agent.
    Type: Application
    Filed: April 29, 2016
    Publication date: May 3, 2018
    Inventors: Gail K. Naughton, Frank Zeigler, Emmett Pinney
  • Publication number: 20150086520
    Abstract: The present invention provides cell compositions and methods of using treating disorders, such as inflammatory disorders, such as atherosclerosis and cardiovascular disease.
    Type: Application
    Filed: March 14, 2013
    Publication date: March 26, 2015
    Inventors: Kelly Ledford, Ronna L. Bartel, Frank Zeigler
  • Publication number: 20140356323
    Abstract: The present invention provides compositions comprising isolated human collagen, isolated human elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation.
    Type: Application
    Filed: August 18, 2014
    Publication date: December 4, 2014
    Inventors: Laura E. Niklason, Yuling Li, Juliana Blum, Shannon L.M. Dahl, Geoffrey Erickson, Frank Zeigler
  • Publication number: 20140193375
    Abstract: The present invention provides compositions of mesenchymal stromal cells which express B7-H3, their subsequent use in tissue repair, improved methods of producing tissue repair cells and method of producing a substantially pure population of CD14+ autofluorescent macrophages.
    Type: Application
    Filed: May 18, 2012
    Publication date: July 10, 2014
    Applicant: AASTROM BIOSCIENCES, INC.
    Inventors: Frank Zeigler, Ronnda L. Bartel
  • Publication number: 20140099292
    Abstract: The present invention provides CD 14+ cell compositions and methods of using same in treating disorders, such as inflammatory disorders, such as atherosclerosis and cardiovascular disease.
    Type: Application
    Filed: September 25, 2013
    Publication date: April 10, 2014
    Applicant: Aastrom Biosciences, Inc.
    Inventors: Kelly Ledford, Ronnda L. Bartel, Frank Zeigler
  • Publication number: 20130002055
    Abstract: A handle for a small electric handheld appliance in which the handle comprises a motor assembly disposed in the handle. The motor assembly comprises a generally L-shaped magnetic yoke formed from two substantially perpendicular surfaces, such that the two substantially perpendicular surfaces define a concave receiving portion. The motor assembly also comprises an iron core and a coil winding disposed substantially in the concave receiving portion, such that the iron core and the coil winding are free from contact with one of the two substantially perpendicular surfaces when the motor is at rest.
    Type: Application
    Filed: May 22, 2012
    Publication date: January 3, 2013
    Inventors: Alexander Doll, Uwe Schober, Frank Peter Kressmann, Frank Zeigler
  • Publication number: 20120230950
    Abstract: The present invention provides compositions comprising isolated human collagen, isolated human elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation.
    Type: Application
    Filed: May 21, 2012
    Publication date: September 13, 2012
    Applicant: Humacyte, Inc.
    Inventors: Laura Niklason, Yuling Li, Juliana Blum, Shannon Dahl, Geoffrey Erickson, Frank Zeigler
  • Patent number: 8198245
    Abstract: The present invention provides compositions comprising isolated human collagen, isolated human elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation.
    Type: Grant
    Filed: July 24, 2008
    Date of Patent: June 12, 2012
    Assignee: Humacyte, Inc.
    Inventors: Laura Niklason, Yuling Li, Juliana Blum, Shannon Dahl, Geoffrey Erickson, Frank Zeigler
  • Publication number: 20090028817
    Abstract: The present invention provides compositions comprising isolated human collagen, isolated human elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation.
    Type: Application
    Filed: July 24, 2008
    Publication date: January 29, 2009
    Inventors: Laura Niklason, Yuling Li, Juliana Blum, Shannon Dahl, Geoffrey Erickson, Frank Zeigler