Patents by Inventor Frank Zheng
Frank Zheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11731061Abstract: A system and method to partially vaporize a process or feed water stream does so in a liquid pool zone of a vessel as the stream comes into contact with a heating medium that is less volatile than the process stream. To keep the pool hot, the heating medium can be recirculated through a heater of a pump-around loop or a heater can be placed in the liquid pool. As the process stream is partially vaporized, any solids present in the process stream together with the unvaporized process or feed water stream move into the heating medium. These solids and unvaporized liquids may be further removed from the heating medium in the pool or in the pump-around loop. The vaporized process stream can be further condensed. Any heat recovered can be used to pre-heat the process stream or in the pump-around loop's heater in case of mechanical vapor recovery.Type: GrantFiled: December 14, 2020Date of Patent: August 22, 2023Assignee: CAMERON SOLUTIONS, INC.Inventors: Z. Frank Zheng, Christopher Stephen King, Harihara V. Nemmara
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Publication number: 20230192749Abstract: Protected fluorescent reagent compounds and their methods of synthesis are provided. The compounds are useful in various fluorescence-based analytical methods, including the analysis of highly multiplexed optical reactions in large numbers at high densities, such as single molecule real time nucleic acid sequencing reactions. The compounds contain fluorescent dye elements, that allow the compounds to be detected with high sensitivity at desirable wavelengths, binding elements, that allow the compounds to be recognized specifically by target biomolecules, and protective shield elements, that decrease undesirable contacts between the fluorescent dye elements and the bound target biomolecules and that therefore decrease photodamage of the bound target biomolecules by the fluorescent dye elements.Type: ApplicationFiled: February 10, 2023Publication date: June 22, 2023Applicant: Pacific Biosciences of California, Inc.Inventors: Lubomir SEBO, Jeremiah HANES, Gene SHEN, Louis BROGLEY, Stephen YUE, Frank ZHENG, Yuri LAPIN, John LYLE, Honey OSUNA, Andrei FEDOROV
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Patent number: 11578093Abstract: Protected fluorescent reagent compounds and their methods of synthesis are provided. The compounds are useful in various fluorescence-based analytical methods, including the analysis of highly multiplexed optical reactions in large numbers at high densities, such as single molecule real time nucleic acid sequencing reactions. The compounds contain fluorescent dye elements, that allow the compounds to be detected with high sensitivity at desirable wavelengths, binding elements, that allow the compounds to be recognized specifically by target biomolecules, and protective shield elements, that decrease undesirable contacts between the fluorescent dye elements and the bound target biomolecules and that therefore decrease photodamage of the bound target biomolecules by the fluorescent dye elements.Type: GrantFiled: August 28, 2020Date of Patent: February 14, 2023Assignee: Pacific Biosciences of California, Inc.Inventors: Lubomir Sebo, Jeremiah Hanes, Gene Shen, Louis Brogley, Stephen Yue, Frank Zheng, Yuri Lapin, John Lyle, Honey Osuna, Andrei Fedorov
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Patent number: 11524927Abstract: Monoethylene glycol (MEG) may be reclaimed by a process that includes contacting a MEG-water-salt stream with a heat transfer fluid and then flash separating the MEG and water in the flash separator vessel where the pressure is higher than 0.3 barA (0.03 MPa), the temperature is in the range of above 120° C. to about 250° C., and the residence time of the MEG and water ranges from about 1 second to about 10 minutes, and then removing the MEG and water in an overhead of the flash separator vessel and removing the salt from the flash separator vessel. In some embodiments it is expected that the temperature of the process may range from above 165° C. to about 250° C. and/or that the pressure may be atmospheric.Type: GrantFiled: July 16, 2015Date of Patent: December 13, 2022Assignee: CAMERON INTERNATIONAL CORPORATIONInventors: Christopher Stephen King, Brian Edward Messenger, Harihara V. Nemmara, Z. Frank Zheng, Shihui Zhou
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Patent number: 11414328Abstract: A vessel for treating an oil-in-water inlet stream houses an inlet flow distributor arranged to direct an inlet flow toward a perforated baffle of a coalescing section, the coalescing section housing a packing and being arranged upstream of a second baffle; a flotation section arranged to receive a flow exiting the coalescing section and being divided by one or more perforated baffles; and an outlet water collecting pipe arranged to receive a flow exiting the flotation section, the outlet water collecting pipe having one or more openings located along its length. The coalescing section may be divided into two sections, with one section preferably housing a different pre-selected sized packing than the other section. The flotation section may include one or more gas-inducing devices. A solid baffle may be arranged downstream of the second baffle and ahead of the flotation section to provide single or dual flow through that section.Type: GrantFiled: April 13, 2020Date of Patent: August 16, 2022Assignee: CAMERON INTERNATIONAL CORPORATIONInventors: Joseph Min-Hsiun Lee, Gary W. Sams, Z. Frank Zheng
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Publication number: 20210268398Abstract: A system and method to partially vaporize a process or feed water stream does so in a liquid pool zone of a vessel as the stream comes into contact with a heating medium that is less volatile than the process stream. To keep the pool hot, the heating medium can be recirculated through a heater of a pump-around loop or a heater can be placed in the liquid pool. As the process stream is partially vaporized, any solids present in the process stream together with the unvaporized process or feed water stream move into the heating medium. These solids and unvaporized liquids may be further removed from the heating medium in the pool or in the pump-around loop. The vaporized process stream can be further condensed. Any heat recovered can be used to pre-heat the process stream or in the pump-around loop's heater in case of mechanical vapor recovery.Type: ApplicationFiled: December 14, 2020Publication date: September 2, 2021Inventors: Z. Frank Zheng, Christopher Stephen King, Harihara V. Nemmara
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Patent number: 11083974Abstract: A system and method to reboil a process or feed water stream in a distillation system does so in a liquid pool zone of a vessel as the stream is removed from a distillation column and comes into contact with a heating medium that is immiscible with and less volatile than the process stream. To keep the pool hot, the heating medium can be recirculated through a heater of a pump-around loop or a heater can be placed in the liquid pool. As the process stream is partially vaporized, any solids present in the process stream together with the unvaporized process or feed water stream move into the heating medium. These solids and unvaporized liquids may be further removed from the heating medium in the pool or in the pump-around loop. The vaporized stream is returned to the distillation column.Type: GrantFiled: May 16, 2019Date of Patent: August 10, 2021Assignee: CAMERON SOLUTIONS, INC.Inventors: Z. Frank Zheng, Christopher Stephen King, Harihara V. Nemmara, Matthew S. Henley
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Publication number: 20210147465Abstract: Protected fluorescent reagent compounds and their methods of synthesis are provided. The compounds are useful in various fluorescence-based analytical methods, including the analysis of highly multiplexed optical reactions in large numbers at high densities, such as single molecule real time nucleic acid sequencing reactions. The compounds contain fluorescent dye elements, that allow the compounds to be detected with high sensitivity at desirable wavelengths, binding elements, that allow the compounds to be recognized specifically by target biomolecules, and protective shield elements, that decrease undesirable contacts between the fluorescent dye elements and the bound target biomolecules and that therefore decrease photodamage of the bound target biomolecules by the fluorescent dye elements.Type: ApplicationFiled: August 28, 2020Publication date: May 20, 2021Applicant: Pacific Biosciences of California, Inc.Inventors: Lubomir SEBO, Jeremiah HANES, Gene SHEN, Louis BROGLEY, Stephen YUE, Frank ZHENG, Yuri LAPIN, John LYLE, Honey OSUNA, Andrei FEDOROV
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Patent number: 10918966Abstract: A system and method to vaporize a process or feed water stream does so in a liquid pool zone of a vessel as the stream comes into contact with a heating medium that is less volatile than the process stream. To keep the pool hot, the heating medium can be recirculated through a heater of a pump-around loop or a heater can be placed in the liquid pool. As the process stream is vaporized, any solids present in the process stream come out of the process stream and move into the heating medium. These solids may be further removed from the heating medium in the pool or in the pump-around loop. The vaporized process stream can be further condensed. Any heat recovered can be used to pre-heat the process stream or used in the pump around loop's heater in case of mechanical vapor recovery.Type: GrantFiled: May 16, 2019Date of Patent: February 16, 2021Assignee: SCHLUMBERGER TECHNOLOGY CORPORATIONInventors: Z. Frank Zheng, Christopher Stephen King, Harihara V. Nemmara, Brian Edward Messenger
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Patent number: 10864456Abstract: A system and method to partially vaporize a process or feed water stream does so in a liquid pool zone of a vessel as the stream comes into contact with a heating medium that is less volatile than the process stream. To keep the pool hot, the heating medium can be recirculated through a heater of a pump-around loop or a heater can be placed in the liquid pool. As the process stream is partially vaporized, any solids present in the process stream together with the unvaporized process or feed water stream move into the heating medium. These solids and unvaporized liquids may be further removed from the heating medium in the pool or in the pump-around loop. The vaporized process stream can be further condensed. Any heat recovered can be used to pre-heat the process stream or in the pump-around loop's heater in case of mechanical vapor recovery.Type: GrantFiled: May 16, 2019Date of Patent: December 15, 2020Assignee: CAMERON SOLUTIONS, INC.Inventors: Z. Frank Zheng, Christopher Stephen King, Harihara V. Nemmara
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Patent number: 10800805Abstract: Protected fluorescent reagent compounds and their methods of synthesis are provided. The compounds are useful in various fluorescence-based analytical methods, including the analysis of highly multiplexed optical reactions in large numbers at high densities, such as single molecule real time nucleic acid sequencing reactions. The compounds contain fluorescent dye elements, that allow the compounds to be detected with high sensitivity at desirable wavelengths, binding elements, that allow the compounds to be recognized specifically by target biomolecules, and protective shield elements, that decrease undesirable contacts between the fluorescent dye elements and the bound target biomolecules and that therefore decrease photodamage of the bound target biomolecules by the fluorescent dye elements.Type: GrantFiled: April 30, 2018Date of Patent: October 13, 2020Assignee: Pacific Biosciences of California, Inc.Inventors: Lubomir Sebo, Jeremiah Hanes, Gene Shen, Louis Brogley, Stephen Yue, Frank Zheng, Yuri Lapin, John Lyle, Honey Osuna, Andrei Fedorov
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Patent number: 10794167Abstract: Embodiments described herein provide methods of operating a linear contactor for absorbing contaminants from a gas stream. The gas stream flows from a first end to a second end of the linear contactor. Fresh absorbent is provided at the first end of the linear contactor based on the theoretical minimum amount of absorbent needed to remove the contaminants. Absorbent is recycled from the second end to the first end of the linear contactor. Fresh absorbent is provided at the second end based on chemical condition of the recycled absorbent. Apparatus for practicing the method is also described.Type: GrantFiled: December 4, 2018Date of Patent: October 6, 2020Assignee: SCHLUMBERGER TECHNOLOGY CORPORATIONInventors: Z. Frank Zheng, Dahai Tang, Sandrine Hoebler, Matthew J. Hull, Gary W. Sams, Ankur D. Jariwala
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Patent number: 10787573Abstract: Multimeric protected fluorescent reagents and their methods of synthesis are provided. The reagents are useful in various fluorescence-based analytical methods, including the analysis of highly multiplexed optical reactions in large numbers at high densities, such as single molecule real time nucleic acid sequencing reactions. The reagents contain fluorescent dye elements, that allow the compounds to be detected with high sensitivity at desirable wavelengths, binding elements, that allow the compounds to be recognized specifically by target biomolecules, and protective shield elements, that decrease undesirable contacts between the fluorescent dye elements and the bound target biomolecules and that therefore decrease photodamage of the bound target biomolecules by the fluorescent dye elements. The reagents also contain coupling elements connect monomeric compounds into multimeric forms, thereby increasing brightness.Type: GrantFiled: December 4, 2018Date of Patent: September 29, 2020Assignee: Pacific Biosciences of California, Inc.Inventors: Frank Zheng, Jeremiah Hanes, Gene Shen, Louis Brogley, Stephen Yue, Yuri Lapin, John Lyle, Honey Osuna, Andrei Fedorov, Lubomir Sebo
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Publication number: 20200239335Abstract: A vessel for treating an oil-in-water inlet stream houses an inlet flow distributor arranged to direct an inlet flow toward a perforated baffle of a coalescing section, the coalescing section housing a packing and being arranged upstream of a second baffle; a flotation section arranged to receive a flow exiting the coalescing section and being divided by one or more perforated baffles; and an outlet water collecting pipe arranged to receive a flow exiting the flotation section, the outlet water collecting pipe having one or more openings located along its length. The coalescing section may be divided into two sections, with one section preferably housing a different pre-selected sized packing than the other section. The flotation section may include one or more gas-inducing devices. A solid baffle may be arranged downstream of the second baffle and ahead of the flotation section to provide single or dual flow through that section.Type: ApplicationFiled: April 13, 2020Publication date: July 30, 2020Inventors: Joseph Min-Hsiun Lee, Gary W. Sams, Z. Frank Zheng
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Publication number: 20200179866Abstract: Embodiments described herein provide methods of removing contaminants from a gas, the methods including providing a feed gas to a vertical contactor; flowing the feed gas in a gas flow direction through the vertical contactor; mixing a fresh absorbent makeup with a recycled absorbent to form an absorbent mixture; providing a fresh absorbent feed to the feed gas; flowing the absorbent mixture through the vertical contactor in a liquid flow direction counter to the gas flow direction; recovering a clean gas stream from the vertical contactor; and recovering the recycled absorbent from the vertical contactor.Type: ApplicationFiled: December 6, 2018Publication date: June 11, 2020Inventors: Z. Frank Zheng, Dahai Tang, Sandrine Hoebler, Matthew J. Hull, Gary W. Sams, Ankur D. Jariwala
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Publication number: 20200173266Abstract: Embodiments described herein provide methods of operating a linear contactor for absorbing contaminants from a gas stream. The gas stream flows from a first end to a second end of the linear contactor. Fresh absorbent is provided at the first end of the linear contactor based on the theoretical minimum amount of absorbent needed to remove the contaminants. Absorbent is recycled from the second end to the first end of the linear contactor. Fresh absorbent is provided at the second end based on chemical condition of the recycled absorbent. Apparatus for practicing the method is also described.Type: ApplicationFiled: December 4, 2018Publication date: June 4, 2020Inventors: Z. Frank Zheng, Dahai Tang, Sandrine Hoebler, Matthew J. Hull, Gary W. Sams, Ankur D. Jariwala
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Patent number: 10618825Abstract: A vessel for treating an oil-in-water inlet stream houses an inlet flow distributor arranged to direct an inlet flow toward a perforated baffle of a coalescing section, the coalescing section housing a packing and being arranged upstream of a second baffle; a flotation section arranged to receive a flow exiting the coalescing section and being divided by one or more perforated baffles; and an outlet water collecting pipe arranged to receive a flow exiting the flotation section, the outlet water collecting pipe having one or more openings located along its length. The coalescing section may be divided into two sections, with one section preferably housing a different pre-selected sized packing than the other section. The flotation section may include one or more gas-inducing devices. A solid baffle may be arranged downstream of the second baffle and ahead of the flotation section to provide single or dual flow through that section.Type: GrantFiled: December 5, 2016Date of Patent: April 14, 2020Assignee: CAMERON SOLUTIONS INC.Inventors: Joseph Min-Hsiun Lee, Gary W. Sams, Z. Frank Zheng
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Publication number: 20200079713Abstract: Monoethylene glycol (MEG) may be reclaimed by a process that includes contacting a MEG-water-salt stream with a heat transfer fluid and then flash separating the MEG and water in the flash separator vessel where the pressure is higher than 0.3 barA (0.03 MPa), the temperature is in the range of above 120° C. to about 250° C., and the residence time of the MEG and water ranges from about 1 second to about 10 minutes, and then removing the MEG and water in an overhead of the flash separator vessel and removing the salt from the flash separator vessel. In some embodiments it is expected that the temperature of the process may range from above 165° C. to about 250° C. and/or that the pressure may be atmospheric.Type: ApplicationFiled: November 11, 2019Publication date: March 12, 2020Applicant: Cameron International CorporationInventors: Christopher Stephen King, Brian Edward Messenger, Harihara V. Nemmara, Z. Frank Zheng, Shihui Zhou
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Publication number: 20200039843Abstract: A system and method to reboil a process or feed water stream in a distillation system does so in a liquid pool zone of a vessel as the stream is removed from a distillation column and comes into contact with a heating medium that is immiscible with and less volatile than the process stream. To keep the pool hot, the heating medium can be recirculated through a heater of a pump-around loop or a heater can be placed in the liquid pool. As the process stream is partially vaporized, any solids present in the process stream together with the unvaporized process or feed water stream move into the heating medium. These solids and unvaporized liquids may be further removed from the heating medium in the pool or in the pump-around loop. The vaporized stream is returned to the distillation column.Type: ApplicationFiled: May 16, 2019Publication date: February 6, 2020Inventors: Z. Frank Zheng, Christopher Stephen King, Harihara V. Nemmara, Matthew S. Henley
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Patent number: 10478745Abstract: A system and method to vaporize a process or feed water stream does so in a liquid pool zone of a vessel as the stream comes into contact with a heating medium that is less volatile than the process stream. To keep the pool hot, the heating medium can be recirculated through a heater of a pump-around loop or a heater can be placed in the liquid pool. As the process stream is vaporized, any solids present in the process stream come out of the process stream and move into the heating medium. These solids may be further removed from the heating medium in the pool or in the pump-around loop. The vaporized process stream can be further condensed. Any heat recovered can be used to pre-heat the process stream or used in the pump around loop's heater in case of mechanical vapor recovery.Type: GrantFiled: June 27, 2016Date of Patent: November 19, 2019Assignee: CAMERON SOLUTIONS, INC.Inventors: Z. Frank Zheng, Christopher Stephen King, Harihara V. Nemmara, Brian Edward Messenger