Abstract: There is provided a system of controlling account logon rights on one or more computer systems based on multifactor authentication (MFA), the system comprising a processing circuitry (PC) adapted to: configure respective logon rights control facilities of the one or more computer systems, to, at least, deny logon rights of a first account in, at least, a first logon type; responsive to detecting, in a logon logging facility of a first computer system of the one or more computer systems, an event of denying logon rights to the first account by the logon rights control facility, initiate a sequence of authentication of the first user; responsive to successful completion of the sequence of authentication, configure the logon rights control facility of the first computer system to remove denial of logon rights to the first account in, at least, the first logon type, thereby performing an MFA process

Abstract: A medication adherence and monitoring system and method for use with pill packet dosing is provided. The system is configured to mount on a medication reservoir that stores a stream of pill packets. The system utilizes a processor in conjunction with an optical scanner, to read scannable codes on the stream of pill packets to configure the system and track extraction of the pill packets from the reservoir when they pass by the optical scanner as the pill packets are extracted from the reservoir through an opening in a housing that spans or covers a storage container for the pill packets. The system further provides prompting and feedback for the extraction of the pill packets while monitoring compliance with the dosage schedule for the user.

Abstract: A forest fire retardant composition contains a retardant compound that includes a potassium salt. The potassium salt may include a potassium salt of an organic acid, a potassium salt of an inorganic acid, or mixtures thereof. The organic acid may include formic acid, acetic acid, propanoic acid, butanoic acid, lactic acid, oxalic acid, malic acid, gluconic acid, tartaric acid, uric acid, malic acid, or citric acid. The inorganic acid may include sulfuric acid, phosphoric acid, carbonic acid, or hydrochloric acid. The composition may be in the form of a dry concentrate, a liquid concentrate, or a final diluted product. The final diluted product is effective in suppressing, retarding, and controlling forest fires while exhibiting corrosion resistance and low toxicity.

Abstract: RNA interference-based methods and products for inhibiting the expression of pathogenic dynamin-1 variants are provided. Delivery vehicles such as recombinant adeno-associated viruses deliver DNAs encoding RNAs that inhibit the expression of the dynamin-1 variants. The methods treat, for example, developmental and epileptic encephalopathies.

Abstract: A method of modeling an optical system includes obtaining input data for a channel in an optical system that includes a transmitter, one or more spans, and a receiver; processing the input data with a transmitter sub-model, output data from the transmitter sub-model with one or more span sub-models, and output data from one or more span sub-models with a receiver sub-model; and providing output data for the channel based on the processing. The method can also include, prior to the receiving, training an optical system model for the optical system; and decomposing the optical system model into the transmitter sub-model, the one or more span sub-models, and the receiver sub-model.

Abstract: An optical bypass system for interconnecting a plurality of data centers with a regional hub networking node includes an optical switching layer configured to receive a plurality of channels from each of the plurality of data centers, and to switch the plurality of channels from each of the plurality of data centers (1) between one another for optical bypass and (2) to an electrical switching fabric at the regional hub networking node; and a controller configured to (1) configure wavelengths on corresponding optical transceivers for each of the plurality of channels from each of the plurality of data centers, (2) configure wavelength switching in the optical switching layer, and (3) determine packet forwarding between the corresponding optical transceivers.

Abstract: The present disclosure provides an ethylene-based polymer. The ethylene-based polymer is formed from reacting, under polymerization conditions, ethylene monomer and bisallyl maleate (“BAIIM”). The present ethylene-based polymer with ethylene monomer and bisallyl maleate branching agent is interchangeably referred to as “BAIIM-PE.

Abstract: A satellite includes a plurality of transceivers, each configured to selectively connect to one of another transceiver in another satellite and a ground station; and configurable pass-through between the plurality of transceivers that is configured based on a location of the satellite in a constellation. The configurable pass-through can provide data signal pass-through without one or more of full decoding, regeneration, and error correction, thereby saving power.

Abstract: The present disclosure relates in some aspects to methods, compositions and uses involving immunotherapies, such as adoptive cell therapy, e.g., T cell therapy, and an immunomodulatory compound, such as a structural or functional analog or derivative of thalidomide and/or an inhibitor of E3-ubiquitin ligase. The provided methods, compositions and uses include those for combination therapies involving the administration or use of one or more immunomodulatory compounds in conjunction with a T cell therapy, such as a genetically engineered T cell therapy involving cells engineered with a recombinant receptor, such as chimeric antigen receptor (CAR)-expressing T cells. Also provided are compositions, methods of administration to subjects, articles of manufacture and kits for use in the methods.

Abstract: A Photonic Integrated Circuit (PIC) includes N Ring and Disk type Microstructures (RDMs), N is an integer and greater than 1; at least one spare RDM, wherein each RDM operates spectrally in a periodic nature and has its spectral operation vary by temperature; and circuitry configured to handoff any of the N RDMs and the at least one spare RDM for spectral operation based on a current temperature. For the handoff, the at least one spare RDM is unlocked spectrally and is tuned and locked to a frequency of interest of a current RDM based on the temperature, and the current RDM is unlocked.

Abstract: An apparatus and method for mounting a payload to a flight system. The apparatus includes a first arm, a second arm, a first member, a second member, and at least four attachment interfaces, attached to at least the payload and the flight system.

Abstract: A wastewater filter cartridge includes a peripheral frame, two filter media sheets, two sets of angled fins, and a filtered water outlet. The two filter media sheets are attached to the peripheral frame in spaced face-to-face relation such that they combine with the peripheral frame to define an interior volume within the filter cartridge. At the same time, the two sets of angled fins are attached to the peripheral frame external to the interior volume and project away from the filter media sheets at oblique angles. As wastewater passes through the two filter media sheets into the interior of the filter cartridge, the two filter media sheets act to reduce the suspended solids in the wastewater. Once in the interior volume of the filter cartridge, the filtered water is collected via the filtered water outlet, which is connected to the interior volume.

Abstract: An expandable vertebral body device, system, instrument, and methods of assembly and using the device, system, and instrument are disclosed. The vertebral body device includes a body with a first end and a second end, a first rotating member rotatably coupled to the first end, a second rotating member rotatably coupled to the second end, a first extension member moveably coupled to the first end, and a second extension member moveably coupled to the second end. The expandable cage system comprises a vertebral body device and an insertion instrument. Methods for assembling and using the vertebral body device and instrument are also disclosed.

Abstract: An activity stream based interaction model is disclosed. To cause a desired application level action to be performed at a remote system, such as automatically retrieving and displaying a document in a viewer or other portion of a user interface at the remote system, a text-based tag, such as a hash tag, is inserted into an activity stream. The activity stream is sent to the remote system, which is configured to respond to the text-based tag by performing, at least in part automatically, the corresponding application level action.

Abstract: Disclosed electroencephalogram (EEG) monitoring and detection systems and methods can detect differentiated electrographic seizure characteristics of different seizure types across a diverse group of patients. Disclosed systems and methods can utilize EEG data collected by discrete wireless EEG sensors positioned on a scalp of a patient.

Abstract: Aspects of the subject disclosure may include, for example, obtaining an estimate of a phase of a reference associated with a signal received over an optical channel, obtaining an estimate of a frequency of a carrier associated with the signal, and based on the estimate of the phase of the reference and the estimate of the frequency of the carrier, estimating a location dependent property associated with a disturbance to the optical channel to determine a location estimate for the disturbance. Other embodiments are disclosed.

Abstract: Exemplary alloys may be particularly suited for additive manufacturing applications, and may comprise iron and one or more of: chromium (Cr), nickel (Ni), carbon (C), and copper (Cu). Exemplary alloys may have a majority microstructure that is martensite.

Abstract: A reactor for coating particles includes a stationary vacuum chamber to hold a bed of particles to be coated, a chemical delivery system, and a paddle assembly. The paddle assembly includes a rotatable drive shaft and a first plurality of paddles and a second plurality of paddles that extend radially from the drive shaft. The spacing, cross-sections, and oblique angles of the paddles are such that orbiting of the paddles causes the first plurality of paddles and the second plurality of paddles to displace substantially equal volumes in opposite directions in the lower portion of the stationary vacuum chamber.

Abstract: Systems and methods include an optical transceiver configured to connect to a fiber cable having a plurality of fiber cores, the optical transceiver including a plurality of transmitters, and a plurality of receivers, wherein the transmitters connect to a first set of the fiber cores in the fiber cable and the receivers connect to a second set of the fiber cores of the fiber cable. The optical transceiver including an array composed of the elements where each element consists of a ?LED and a Photodetector connected to a programmable wire such that a training algorithm selects which wires become active in the data path. Associated circuitry such as drivers for ?LEDs and TIAs for PDs are also part of each element.

Abstract: Described herein are multicistronic expression systems that encode chimeric proteins, specifically membrane-cleavable chimeric systems and chimeric antigen receptors. Also described herein are nucleic acids, cells, and methods directed to the same.