Patents by Inventor Franklin R. Cockerill, III
Franklin R. Cockerill, III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8535888Abstract: The present invention relates to methods of detecting the presence or absence of methicillin-resistant S. aureus (MRSA) in a sample, the method comprising performing an amplifying step, a hybridizing step and a detecting step. Furthermore, the present invention relates to primers, probes and kits for the detection of MRSA.Type: GrantFiled: December 28, 2007Date of Patent: September 17, 2013Assignees: Mayo Foundation for Medical Education and Research, Roche Molecular SystemsInventors: Christian Aichinger, Astrid Reiser, James R. Uhl, Franklin R. Cockerill, III
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Patent number: 8507201Abstract: The invention provides methods to detect Bordetella pertussis and/or Bordetella parapertussis in a biological sample. Primers and probes for the differential detection of B. pertussis and B. parapertussis are provided by the invention. Articles of manufacture containing such primers and probes for detecting B. pertussis and/or B. parapertussis are further provided by the invention.Type: GrantFiled: November 17, 2009Date of Patent: August 13, 2013Assignees: Mayo Foundation for Medical Education and Research, Roche Molecular Systems, Inc.Inventors: Franklin R Cockerill, III, Robin Patel, Lynne M Sloan, Sabine Lohmann, Ulrike Salat
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Patent number: 8362227Abstract: The invention provides methods to detect C. difficile in biological samples using real-time PCR. Primers and probes for the detection of C. difficile are provided by the invention. Articles of manufacture containing such primers and probes for detecting C. difficile are further provided by the invention.Type: GrantFiled: January 9, 2012Date of Patent: January 29, 2013Assignee: Mayo Foundation for Medical Education and ResearchInventors: Franklin R. Cockerill, III, Thomas F. Smith, Jon E. Rosenblatt, Lynne M. Sloan
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Publication number: 20120107819Abstract: The invention provides methods to detect C. difficile in biological samples using real-time PCR. Primers and probes for the detection of C. difficile are provided by the invention. Articles of manufacture containing such primers and probes for detecting C. difficile are further provided by the invention.Type: ApplicationFiled: January 9, 2012Publication date: May 3, 2012Inventors: Franklin R. Cockerill, III, Thomas F. Smith, Jon E. Rosenblatt, Lynne M. Sloan
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Patent number: 8101362Abstract: The invention provides methods to detect C. difficile in biological samples using real-time PCR. Primers and probes for the detection of C. difficile are provided by the invention. Articles of manufacture containing such primers and probes for detecting C. difficile are further provided by the invention.Type: GrantFiled: February 6, 2009Date of Patent: January 24, 2012Assignee: Mayo Foundation for Medical Education and ResearchInventors: Franklin R. Cockerill, III, Thomas F. Smith, Jon E. Rosenblatt, Lynne M. Sloan
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Patent number: 8097413Abstract: The invention provides methods to detect group B streptococcus (GBS) in biological samples using real-time PCR. Primers and probes for the detection of GBS are provided by the invention. Articles of manufacture containing such primers and probes for detecting GBS are further provided by the invention.Type: GrantFiled: July 26, 2010Date of Patent: January 17, 2012Assignees: Mayo Foundation for Medical Education and Research, Roche Molecular SystemsInventors: James R Uhl, Franklin R Cockerill, III, Christian Aichinger, Astrid Reiser
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Publication number: 20100291582Abstract: The invention provides methods to detect group B streptococcus (GBS) in biological samples using real-time PCR. Primers and probes for the detection of GBS are provided by the invention. Articles of manufacture containing such primers and probes for detecting GBS are further provided by the invention.Type: ApplicationFiled: July 26, 2010Publication date: November 18, 2010Inventors: James R. Uhl, Franklin R. Cockerill, III, Christian Aichinger, Astrid Reiser
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Publication number: 20100227322Abstract: The invention provides methods to detect Bordetella pertussis and/or Bordetella parapertussis in a biological sample. Primers and probes for the differential detection of B. pertussis and B. parapertussis are provided by the invention. Articles of manufacture containing such primers and probes for detecting B. pertussis and/or B. parapertussis are further provided by the invention.Type: ApplicationFiled: November 17, 2009Publication date: September 9, 2010Inventors: Franklin R. Cockerill, III, Robin Patel, Lynne M. Sloan, Sabine Lohmann, Ulrike Salat
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Patent number: 7790875Abstract: The invention provides methods to detect group B streptococcus (GBS) in biological samples using real-time PCR. Primers and probes for the detection of GBS are provided by the invention. Articles of manufacture containing such primers and probes for detecting GBS are further provided by the invention.Type: GrantFiled: September 23, 2008Date of Patent: September 7, 2010Assignees: Mayo Foundation for Medical Education and Research, Roche Molecular Systems, Inc.Inventors: James R. Uhl, Franklin R. Cockerill, III, Christian Aichinger, Astrid Reiser
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Publication number: 20100221715Abstract: The invention provides methods to detect Bordetella pertussis and/or Bordetella parapertussis in a biological sample. Primers and probes for the differential detection of B. pertussis and B. parapertussis are provided by the invention. Articles of manufacture containing such primers and probes for detecting B. pertussis and/or B. parapertussis are further provided by the invention.Type: ApplicationFiled: November 17, 2009Publication date: September 2, 2010Inventors: Franklin R. Cockerill, III, Robin Patel, Lynne M. Sloan, Sabine Lohmann, Ulrike Salat
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Patent number: 7691571Abstract: The invention provides methods to detect Bordetella pertussis and/or Bordetella parapertussis in a biological sample. Primers and probes for the differential detection of B. pertussis and B. parapertussis are provided by the invention. Articles of manufacture containing such primers and probes for detecting B. pertussis and/or B. parapertussis are further provided by the invention.Type: GrantFiled: January 9, 2004Date of Patent: April 6, 2010Assignees: Mayo Foundation for Medical Education and Research, Roche Molecular Systems, Inc.Inventors: Franklin R. Cockerill, III, Robin Patel, Lynne M. Sloan, Sabine Lohmann, Ulrike Salat
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Publication number: 20090203021Abstract: The invention provides methods to detect C. difficile in biological samples using real-time PCR. Primers and probes for the detection of C. difficile are provided by the invention. Articles of manufacture containing such primers and probes for detecting C. difficile are further provided by the invention.Type: ApplicationFiled: February 6, 2009Publication date: August 13, 2009Inventors: Franklin R. Cockerill, III, Thomas F. Smith, Jon E. Rosenblatt, Lynne M. Sloan
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Publication number: 20090171245Abstract: This disclosure describes a swab extraction device that can be used to collect a medical specimen, transport the specimen to a laboratory, and process and analyze the specimen.Type: ApplicationFiled: May 3, 2007Publication date: July 2, 2009Inventors: James R. Uhl, Franklin R. Cockerill III, Christian Aichinger
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Publication number: 20090111111Abstract: The invention provides methods to detect group B streptococcus (GBS) in biological samples using real-time PCR. Primers and probes for the detection of GBS are provided by the invention. Articles of manufacture containing such primers and probes for detecting GBS are further provided by the invention.Type: ApplicationFiled: September 23, 2008Publication date: April 30, 2009Inventors: James R. Uhl, Franklin R. Cockerill, III, Christian Aichinger, Astrid Reiser
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Patent number: 7427475Abstract: The invention provides methods to detect group B streptococcus (GBS) in biological samples using real-time PCR. Primers and probes for the detection of GBS are provided by the invention. Articles of manufacture containing such primers and probes for detecting GBS are further provided by the invention.Type: GrantFiled: November 18, 2003Date of Patent: September 23, 2008Assignee: Mayo Foundation for Medical Education and ResearchInventors: James R. Uhl, Franklin R. Cockerill, III, Christian Aichinger, Astrid Reiser
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Patent number: 7074598Abstract: The invention provides methods to detect vancomycin-resistant enterococci in biological samples using real-time PCR. Primers and probes for the detection of vancomycin-resistant enterococci are provided by the invention. Articles of manufacture containing such primers and probes for detecting vancomycin-resistant enterococci are further provided by the invention.Type: GrantFiled: September 25, 2002Date of Patent: July 11, 2006Assignee: Mayo Foundation for Medical Education and ResearchInventors: Franklin R. Cockerill, III, Lynne M. Sloan
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Patent number: 7074599Abstract: The invention provides methods to detect mecA-containing Staphylococcus spp. in biological samples using real-time PCR. Primers and probes for the detection of S. aureus are provided by the invention. Articles of manufacture containing such primers and probes for detecting mecA-containing Staphylococcus spp. are further provided by the invention.Type: GrantFiled: September 27, 2002Date of Patent: July 11, 2006Assignee: Mayo Foundation for Medical Education and ResearchInventors: James R. Uhl, Franklin R. Cockerill, III
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Patent number: 5922575Abstract: A method for selectively detecting M. tuberculosis is provided employing restriction fragment length polymorphism analysis of an enzymatic digest of the M. tuberculosis katG gene.Type: GrantFiled: May 7, 1997Date of Patent: July 13, 1999Assignee: Mayo Foundation for Medical Education & ResearchInventors: Franklin R. Cockerill, III, Bruce C. Kline, James R. Uhl
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Patent number: 5658733Abstract: A method for determining the susceptibility of a strain of M. tuberculosis to isoniazid is provided comprising employing the techniques of restriction fragment length polymorphism analysis to determine whether or not the DNA of said strain has an MspI restriction site at the codon corresponding to codons 315 or 463 of an M. tuberculosis katG gene consensus sequence.Type: GrantFiled: April 7, 1995Date of Patent: August 19, 1997Assignee: Mayo Foundation For Medical Education And ResearchInventors: Franklin R. Cockerill, III, Bruce C. Kline, James R. Uhl