Patents by Inventor Franklin R. Cockerill, III

Franklin R. Cockerill, III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for detecting methicillin-resistant
    Patent number: 8535888
    Abstract: The present invention relates to methods of detecting the presence or absence of methicillin-resistant S. aureus (MRSA) in a sample, the method comprising performing an amplifying step, a hybridizing step and a detecting step. Furthermore, the present invention relates to primers, probes and kits for the detection of MRSA.
    Type: Grant
    Filed: December 28, 2007
    Date of Patent: September 17, 2013
    Assignees: Mayo Foundation for Medical Education and Research, Roche Molecular Systems
    Inventors: Christian Aichinger, Astrid Reiser, James R. Uhl, Franklin R. Cockerill, III
  • Detection of
    Patent number: 8507201
    Abstract: The invention provides methods to detect Bordetella pertussis and/or Bordetella parapertussis in a biological sample. Primers and probes for the differential detection of B. pertussis and B. parapertussis are provided by the invention. Articles of manufacture containing such primers and probes for detecting B. pertussis and/or B. parapertussis are further provided by the invention.
    Type: Grant
    Filed: November 17, 2009
    Date of Patent: August 13, 2013
    Assignees: Mayo Foundation for Medical Education and Research, Roche Molecular Systems, Inc.
    Inventors: Franklin R Cockerill, III, Robin Patel, Lynne M Sloan, Sabine Lohmann, Ulrike Salat
  • Detection of clostridium difficile
    Patent number: 8362227
    Abstract: The invention provides methods to detect C. difficile in biological samples using real-time PCR. Primers and probes for the detection of C. difficile are provided by the invention. Articles of manufacture containing such primers and probes for detecting C. difficile are further provided by the invention.
    Type: Grant
    Filed: January 9, 2012
    Date of Patent: January 29, 2013
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Franklin R. Cockerill, III, Thomas F. Smith, Jon E. Rosenblatt, Lynne M. Sloan
  • Detection of Clostridium difficile
    Publication number: 20120107819
    Abstract: The invention provides methods to detect C. difficile in biological samples using real-time PCR. Primers and probes for the detection of C. difficile are provided by the invention. Articles of manufacture containing such primers and probes for detecting C. difficile are further provided by the invention.
    Type: Application
    Filed: January 9, 2012
    Publication date: May 3, 2012
    Inventors: Franklin R. Cockerill, III, Thomas F. Smith, Jon E. Rosenblatt, Lynne M. Sloan
  • Detection of
    Patent number: 8101362
    Abstract: The invention provides methods to detect C. difficile in biological samples using real-time PCR. Primers and probes for the detection of C. difficile are provided by the invention. Articles of manufacture containing such primers and probes for detecting C. difficile are further provided by the invention.
    Type: Grant
    Filed: February 6, 2009
    Date of Patent: January 24, 2012
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Franklin R. Cockerill, III, Thomas F. Smith, Jon E. Rosenblatt, Lynne M. Sloan
  • Detection of group B
    Patent number: 8097413
    Abstract: The invention provides methods to detect group B streptococcus (GBS) in biological samples using real-time PCR. Primers and probes for the detection of GBS are provided by the invention. Articles of manufacture containing such primers and probes for detecting GBS are further provided by the invention.
    Type: Grant
    Filed: July 26, 2010
    Date of Patent: January 17, 2012
    Assignees: Mayo Foundation for Medical Education and Research, Roche Molecular Systems
    Inventors: James R Uhl, Franklin R Cockerill, III, Christian Aichinger, Astrid Reiser
  • Detection of Group B Streptococcus
    Publication number: 20100291582
    Abstract: The invention provides methods to detect group B streptococcus (GBS) in biological samples using real-time PCR. Primers and probes for the detection of GBS are provided by the invention. Articles of manufacture containing such primers and probes for detecting GBS are further provided by the invention.
    Type: Application
    Filed: July 26, 2010
    Publication date: November 18, 2010
    Inventors: James R. Uhl, Franklin R. Cockerill, III, Christian Aichinger, Astrid Reiser
  • Detection of Bordetella
    Publication number: 20100227322
    Abstract: The invention provides methods to detect Bordetella pertussis and/or Bordetella parapertussis in a biological sample. Primers and probes for the differential detection of B. pertussis and B. parapertussis are provided by the invention. Articles of manufacture containing such primers and probes for detecting B. pertussis and/or B. parapertussis are further provided by the invention.
    Type: Application
    Filed: November 17, 2009
    Publication date: September 9, 2010
    Inventors: Franklin R. Cockerill, III, Robin Patel, Lynne M. Sloan, Sabine Lohmann, Ulrike Salat
  • Detection of group B
    Patent number: 7790875
    Abstract: The invention provides methods to detect group B streptococcus (GBS) in biological samples using real-time PCR. Primers and probes for the detection of GBS are provided by the invention. Articles of manufacture containing such primers and probes for detecting GBS are further provided by the invention.
    Type: Grant
    Filed: September 23, 2008
    Date of Patent: September 7, 2010
    Assignees: Mayo Foundation for Medical Education and Research, Roche Molecular Systems, Inc.
    Inventors: James R. Uhl, Franklin R. Cockerill, III, Christian Aichinger, Astrid Reiser
  • DETECTION OF BORDETELLA
    Publication number: 20100221715
    Abstract: The invention provides methods to detect Bordetella pertussis and/or Bordetella parapertussis in a biological sample. Primers and probes for the differential detection of B. pertussis and B. parapertussis are provided by the invention. Articles of manufacture containing such primers and probes for detecting B. pertussis and/or B. parapertussis are further provided by the invention.
    Type: Application
    Filed: November 17, 2009
    Publication date: September 2, 2010
    Inventors: Franklin R. Cockerill, III, Robin Patel, Lynne M. Sloan, Sabine Lohmann, Ulrike Salat
  • Detection of bordetella
    Patent number: 7691571
    Abstract: The invention provides methods to detect Bordetella pertussis and/or Bordetella parapertussis in a biological sample. Primers and probes for the differential detection of B. pertussis and B. parapertussis are provided by the invention. Articles of manufacture containing such primers and probes for detecting B. pertussis and/or B. parapertussis are further provided by the invention.
    Type: Grant
    Filed: January 9, 2004
    Date of Patent: April 6, 2010
    Assignees: Mayo Foundation for Medical Education and Research, Roche Molecular Systems, Inc.
    Inventors: Franklin R. Cockerill, III, Robin Patel, Lynne M. Sloan, Sabine Lohmann, Ulrike Salat
  • Detection of Clostridium difficile
    Publication number: 20090203021
    Abstract: The invention provides methods to detect C. difficile in biological samples using real-time PCR. Primers and probes for the detection of C. difficile are provided by the invention. Articles of manufacture containing such primers and probes for detecting C. difficile are further provided by the invention.
    Type: Application
    Filed: February 6, 2009
    Publication date: August 13, 2009
    Inventors: Franklin R. Cockerill, III, Thomas F. Smith, Jon E. Rosenblatt, Lynne M. Sloan
  • SWAB EXTRACTION DEVICE AND METHODS OF USING
    Publication number: 20090171245
    Abstract: This disclosure describes a swab extraction device that can be used to collect a medical specimen, transport the specimen to a laboratory, and process and analyze the specimen.
    Type: Application
    Filed: May 3, 2007
    Publication date: July 2, 2009
    Inventors: James R. Uhl, Franklin R. Cockerill III, Christian Aichinger
  • Detection of Group B Streptococcus
    Publication number: 20090111111
    Abstract: The invention provides methods to detect group B streptococcus (GBS) in biological samples using real-time PCR. Primers and probes for the detection of GBS are provided by the invention. Articles of manufacture containing such primers and probes for detecting GBS are further provided by the invention.
    Type: Application
    Filed: September 23, 2008
    Publication date: April 30, 2009
    Inventors: James R. Uhl, Franklin R. Cockerill, III, Christian Aichinger, Astrid Reiser
  • Detection of group B streptococcus
    Patent number: 7427475
    Abstract: The invention provides methods to detect group B streptococcus (GBS) in biological samples using real-time PCR. Primers and probes for the detection of GBS are provided by the invention. Articles of manufacture containing such primers and probes for detecting GBS are further provided by the invention.
    Type: Grant
    Filed: November 18, 2003
    Date of Patent: September 23, 2008
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: James R. Uhl, Franklin R. Cockerill, III, Christian Aichinger, Astrid Reiser
  • Detection of vancomycin-resistant enterococcus spp.
    Patent number: 7074598
    Abstract: The invention provides methods to detect vancomycin-resistant enterococci in biological samples using real-time PCR. Primers and probes for the detection of vancomycin-resistant enterococci are provided by the invention. Articles of manufacture containing such primers and probes for detecting vancomycin-resistant enterococci are further provided by the invention.
    Type: Grant
    Filed: September 25, 2002
    Date of Patent: July 11, 2006
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Franklin R. Cockerill, III, Lynne M. Sloan
  • Detection of -containing spp.
    Patent number: 7074599
    Abstract: The invention provides methods to detect mecA-containing Staphylococcus spp. in biological samples using real-time PCR. Primers and probes for the detection of S. aureus are provided by the invention. Articles of manufacture containing such primers and probes for detecting mecA-containing Staphylococcus spp. are further provided by the invention.
    Type: Grant
    Filed: September 27, 2002
    Date of Patent: July 11, 2006
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: James R. Uhl, Franklin R. Cockerill, III
  • Mutations in the katG gene useful for detection of M. tuberculosis
    Patent number: 5922575
    Abstract: A method for selectively detecting M. tuberculosis is provided employing restriction fragment length polymorphism analysis of an enzymatic digest of the M. tuberculosis katG gene.
    Type: Grant
    Filed: May 7, 1997
    Date of Patent: July 13, 1999
    Assignee: Mayo Foundation for Medical Education & Research
    Inventors: Franklin R. Cockerill, III, Bruce C. Kline, James R. Uhl
  • Detection of isoniazid resistant strains of M. tuberculosis
    Patent number: 5658733
    Abstract: A method for determining the susceptibility of a strain of M. tuberculosis to isoniazid is provided comprising employing the techniques of restriction fragment length polymorphism analysis to determine whether or not the DNA of said strain has an MspI restriction site at the codon corresponding to codons 315 or 463 of an M. tuberculosis katG gene consensus sequence.
    Type: Grant
    Filed: April 7, 1995
    Date of Patent: August 19, 1997
    Assignee: Mayo Foundation For Medical Education And Research
    Inventors: Franklin R. Cockerill, III, Bruce C. Kline, James R. Uhl