Patents by Inventor Frans V. Wijnendaele

Frans V. Wijnendaele has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the extraction and purification of proteins from culture media producing them
    Patent number: 4857317
    Abstract: The process is applicable to the supernatant of engineered yeast cells disrupted in the presence of a non-ionic detergent; it comprises the precipitation of contaminants by polyethylene glycol and the treatment of this latter supernatant with either a bivalent metal cation or, after eventual ultrafiltration, with ammonium sulfate.
    Type: Grant
    Filed: April 27, 1987
    Date of Patent: August 15, 1989
    Assignee: SmithKline Biologicals
    Inventors: Frans V. Wijnendaele, Daniel Gilles, Guy Simonet
  • Immunogenic E. coli ST enterotoxin derivatives and compositions containing them
    Patent number: 4314993
    Abstract: E. coli heat stable (ST) enterotoxin derivatives are prepared by reaction of E. coli ST enterotoxin with crosslinking agents for proteins. The so-obtained crosslinked ST enterotoxins show immunogenic activity; they are valuable prophylactic agent for protecting man and animals against diarrheal disease provoked by E. coli enterotoxin and they may be formulated into compositions for intramuscular, subcutaneous or oral administration.
    Type: Grant
    Filed: April 4, 1980
    Date of Patent: February 9, 1982
    Assignee: Smithkline-RIT
    Inventor: Frans V. Wijnendaele