Patents by Inventor Frans Van Roy

Frans Van Roy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method to control tumor progression and invasiveness
    Patent number: 7569668
    Abstract: Described is a method of modulating E-cadherin mediated cell adhesion. More specifically, described is the use of hECRep1a and homologues thereof to modulate and/or control tumor cell invasiveness.
    Type: Grant
    Filed: June 16, 2006
    Date of Patent: August 4, 2009
    Assignees: Vlaams Interuniversitair Instituut Voor Biotechnologie VZW, Universiteit Gent
    Inventors: Frans Van Roy, Geert Berx, Kristin Strumane
  • ?-catenin expressed in heart and testis
    Patent number: 7341866
    Abstract: The present invention relates to a novel ?-catenin with a new, specific expression pattern in mainly heart and testis. The invention further relates to the use of this ?-catenin in the prediction, diagnosis, and/or treatment of cadherin-catenin related diseases, in particular cardiomyopathies and male infertility.
    Type: Grant
    Filed: January 13, 2003
    Date of Patent: March 11, 2008
    Assignee: Vlaams Interuniversitair Instituut voor Biotechnologie VZW
    Inventors: Frans Van Roy, Steven Goossens, Barbara Janssens, Griet Vanpoucke
  • CDNAs encoding catenin-binding proteins with function in signalling and/or gene regulation
    Patent number: 6767720
    Abstract: The invention relates to the field of drug discovery, diagnosis, prognosis and treatment of cancer and neurological disorders. The invention provides among others access to and insight in protein-protein or protein-DNA interactions in a signal transduction or transcriptional pathway controlling cell growth or development throughout a wide range of cells and tissues of the body, and provides means, such as nucleic acid, protein, cells and experimental animals and methods to identify candidate drugs, for example for use in therapy of cancer or neurological disorders. As an example of an alpha-catenin-binding protein with function in intracellular signalling or gene regulation, the invention provides an isolated and/or recombinant nucleic acid or a functional fragment, homologue or derivative thereof, corresponding to a zinc finger gene with a nucleic acid sequence as shown in FIG. 1 and encoding a zinc finger protein, or fragment thereof, capable of complexing with a neurally expressed catenin.
    Type: Grant
    Filed: May 19, 2000
    Date of Patent: July 27, 2004
    Assignee: Vlaams Interuniversitair Instituut voor Biotechnologie VZW
    Inventors: Frans van Roy, Ann van Landschoot, Barbara Janssens
  • Identification of neuroblastoma tumor suppressor genes
    Publication number: 20040132030
    Abstract: The present invention relates to a new tumor suppressor gene family. More specifically the present invention relates to a tumor suppressor involved in suppression of neuroblastoma. Said tumor suppressor is involved in the generation of micronuclei and in the removal of acentric chromosomal fragments that might contain amplified DNA.
    Type: Application
    Filed: June 27, 2003
    Publication date: July 8, 2004
    Inventors: Frans Van Roy, Frank Speleman, Nadine Van Roy, Katrien Staes, Karl Vaderpoele
  • Novel alpha-catenin expressed in heart and testis
    Publication number: 20030165506
    Abstract: The present invention relates to a novel &agr;-catenin with a new, specific expression pattern in mainly heart and testis. The invention further relates to the use of this &agr;-catenin in the prediction, diagnosis, and/or treatment of cadherin-catenin related diseases, in particular cardiomyopathies and male infertility.
    Type: Application
    Filed: January 13, 2003
    Publication date: September 4, 2003
    Inventors: Frans Van Roy, Steven Goossens, Barbara Janssens, Griet Vanpoucke