Patents by Inventor Frantisek Rypacke

Frantisek Rypacke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymer bound elastase inhibitors
    Patent number: 5162307
    Abstract: Pharmaceutical compositions and methods of inhibiting the enzyme elastase and increasing the biological half-life and/or potency in terms of inhibitory activity of the enzyme elastase of peptide compounds is achieved by use of a polymer of the formula P--(L--R).sub.q wherein P is a polymer containing at least one unit of the formula (A.sub.n B.sub.n) wherein A.sub.n B.sub.n is substantially nonbiodegradable, and has an average molecular weight of about 1,000 to 5,000 daltons, L is a covalent bond or a linker group and R is a peptide.
    Type: Grant
    Filed: March 25, 1992
    Date of Patent: November 10, 1992
    Assignees: Board of Trustees of the University of Kentucky, Czechoslovak Academy of Sciences
    Inventors: George A. Digenis, Bushra J. Agha, William R. Banks, Frantisek Rypacke