Patents by Inventor Frantisek Trnka

Frantisek Trnka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical composition containing a mixture of proenzymes and enzymes
    Patent number: 11185587
    Abstract: Pharmaceutical composition containing a mixture of proenzymes and enzymes, containing proenzymes trypsinogen and chymotrypsinogen and enzymes ?-amylase and lipase as active substances, and one or more pharmaceutically acceptable excipients, for simultaneous, separate and subsequent administration of the composition in parenteral or transmucosal way, the composition has anti-proliferative and anti-metastatic effects to cancer tumours and is intended for therapeutic, prophylactic and anti-metastatic use in mammals.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: November 30, 2021
    Inventors: Frantisek Trnka, Pavel Dolezal
  • PHARMACEUTICAL COMPOSITION CONTAINING A MIXTURE OF PROENZYMES AND ENZYMES
    Publication number: 20190247471
    Abstract: Pharmaceutical composition containing a mixture of proenzymes and enzymes, containing proenzymes trypsinogen and chymotrypsinogen and enzymes ?-amylase and lipase as active substances, and one or more pharmaceutically acceptable excipients, for simultaneous, separate and subsequent administration of the composition in parenteral or transmucosal way, the composition has anti-proliferative and anti-metastatic effects to cancer tumours and is intended for therapeutic, prophylactic and anti-metastatic use in mammals.
    Type: Application
    Filed: February 21, 2019
    Publication date: August 15, 2019
    Inventors: Frantisek TRNKA, Pavel DOLEZAL
  • PHARMACEUTICAL COMPOSITION CONTAINING A MIXTURE OF PROENZYMES AND ENZYMES
    Publication number: 20160339085
    Abstract: Pharmaceutical composition containing a mixture of proenzymes and enzymes, containing proenzymes trypsinogen and chymotrypsinogen and enzymes ct-amylase and lipase as active substances, and one or more pharmaceutically acceptable excipients, for simultaneous, separate and subsequent administration of the composition in parenteral or transmucosal way, the composition has anti-proliferative and anti-metastatic effects to cancer tumours and is intended for therapeutic, prophylactic and anti-metastatic use in mammals.
    Type: Application
    Filed: November 24, 2014
    Publication date: November 24, 2016
    Inventors: Frantisek TRNKA, Pavel DOLEZAL
  • Pharmaceutical composition containing an isolated protease proenzyme, amylase, and aprotinin
    Patent number: 5858357
    Abstract: The invention is directed to a pharmaceutical preparation with a modulatory effect on malignant tumors, which contains a combination of protease proenzymes and amylases in a ratio between 1:100 and 100:1 in enzymatic activity units, and a protease inhibitor. The invention is also directed to use of such a preparation to modulate the effects of malignant tumors in humans and animals.
    Type: Grant
    Filed: May 17, 1996
    Date of Patent: January 12, 1999
    Inventors: Frantisek Trnka, Miroslav Rybak, Roman Marek, Ladislav Vavra