Patents by Inventor Franz Baudenbacher
Franz Baudenbacher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11950890Abstract: Devices, systems, and methods for monitoring patient hemodynamic status, systemic vascular resistance, reversal of cardiac and respiratory rates, and patient respiratory volume or effort are disclosed. A peripheral venous pressure is measured and used to detect levels, changes, or problems relating to patient blood volume. The peripheral venous pressure measurement is transformed from the time domain to the frequency domain for analysis. A heart rate frequency is identified, and harmonics of the heart rate frequency are detected and evaluated to determine, among other things, hypovolemia or hypervolemia, systemic vascular resistance, and of cardiac and respiratory rates, and patient respiratory volume or effort.Type: GrantFiled: May 20, 2021Date of Patent: April 9, 2024Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SAInventors: Jonathan Handler, James Martucci, Kyle Hocking, Susan Eagle, Colleen Brophy, Richard Boyer, Franz Baudenbacher
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Publication number: 20210267470Abstract: Devices, systems, and methods for monitoring patient hemodynamic status, systemic vascular resistance, reversal of cardiac and respiratory rates, and patient respiratory volume or effort are disclosed. A peripheral venous pressure is measured and used to detect levels, changes, or problems relating to patient blood volume. The peripheral venous pressure measurement is transformed from the time domain to the frequency domain for analysis. A heart rate frequency is identified, and harmonics of the heart rate frequency are detected and evaluated to determine, among other things, hypovolemia or hypervolemia, systemic vascular resistance, and of cardiac and respiratory rates, and patient respiratory volume or effort.Type: ApplicationFiled: May 20, 2021Publication date: September 2, 2021Inventors: Jonathan Handler, James Martucci, Kyle Hocking, Susan Eagle, Colleen Brophy, Richard Boyer, Franz Baudenbacher
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Publication number: 20210267468Abstract: Peripheral intravenous (IV) waveform analysis (PIVA) systems and methods for determining an intravascular volume status of a living subject and monitoring an IV line functionality of a peripheral IV device are provided. The PIVA system includes a peripheral IV device and a processing device. The peripheral IV device includes a peripheral IV catheter inserted into a vein of the living subject, and a fluid controlling device to control fluid flow from a fluid source to the peripheral IV catheter. The processing device receives peripheral venous signals from the peripheral IV device, performs a spectral analysis on the peripheral venous signals to obtain a peripheral venous pressure frequency spectrum; and performs a statistical analysis on amplitudes of peaks of the peripheral venous pressure frequency spectrum to determine an intravascular volume status of the living subject and/or an IV line functionality of the peripheral IV catheter in real time.Type: ApplicationFiled: May 10, 2021Publication date: September 2, 2021Inventors: Susan S. Eagle, Colleen Brophy, Kyle Mitchell Hocking, Franz Baudenbacher, Richard Boyer
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Publication number: 20210267469Abstract: Devices, systems, and methods for monitoring patient hemodynamic status, systemic vascular resistance, reversal of cardiac and respiratory rates, and patient respiratory volume or effort are disclosed. A peripheral venous pressure is measured and used to detect levels, changes, or problems relating to patient blood volume. The peripheral venous pressure measurement is transformed from the time domain to the frequency domain for analysis. A heart rate frequency is identified, and harmonics of the heart rate frequency are detected and evaluated to determine, among other things, hypovolemia or hypervolemia, systemic vascular resistance, and of cardiac and respiratory rates, and patient respiratory volume or effort.Type: ApplicationFiled: May 20, 2021Publication date: September 2, 2021Inventors: Jonathan Handler, James Martucci, Kyle Hocking, Susan Eagle, Colleen Brophy, Richard Boyer, Franz Baudenbacher
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Patent number: 11039753Abstract: Devices, systems, and methods for monitoring patient hemodynamic status, systemic vascular resistance, reversal of cardiac and respiratory rates, and patient respiratory volume or effort are disclosed. A peripheral venous pressure is measured and used to detect levels, changes, or problems relating to patient blood volume. The peripheral venous pressure measurement is transformed from the time domain to the frequency domain for analysis. A heart rate frequency is identified, and harmonics of the heart rate frequency are detected and evaluated to determine, among other things, hypovolemia or hypervolemia, systemic vascular resistance, and of cardiac and respiratory rates, and patient respiratory volume or effort.Type: GrantFiled: December 15, 2017Date of Patent: June 22, 2021Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SAInventors: Jonathan Handler, James Martucci, Kyle Hocking, Susan Eagle, Colleen Brophy, Richard Boyer, Franz Baudenbacher
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Patent number: 11039754Abstract: Devices, systems, and methods for monitoring patient hemodynamic status, systemic vascular resistance, reversal of cardiac and respiratory rates, and patient respiratory volume or effort are disclosed. A peripheral venous pressure is measured and used to detect levels, changes, or problems relating to patient blood volume. The peripheral venous pressure measurement is transformed from the time domain to the frequency domain for analysis. A heart rate frequency is identified, and harmonics of the heart rate frequency are detected and evaluated to determine, among other things, hypovolemia or hypervolemia, systemic vascular resistance, and of cardiac and respiratory rates, and patient respiratory volume or effort.Type: GrantFiled: August 22, 2018Date of Patent: June 22, 2021Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SAInventors: Jonathan Handler, James Martucci, Kyle Hocking, Susan Eagle, Colleen Brophy, Richard Boyer, Franz Baudenbacher
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Publication number: 20200179601Abstract: One aspect of the present disclosure is a system for hemodynamic resuscitation. The system includes an intravenous access device having a pressure sensor element configured to detect a peripheral venous pressure value in response to an occlusion of a peripheral vein. The system also includes a controller device that is configured to receive a signal from the pressure sensor comprising the peripheral venous pressure value, to process the signal to determine a hemodynamic parameter based on the peripheral venous pressure value, and to generate a resuscitation score based on the hemodynamic parameter.Type: ApplicationFiled: November 15, 2019Publication date: June 11, 2020Inventors: Kevin Sexton, Susan Eagle, Kyle Hocking, Franz Baudenbacher, Colleen Brophy, Richard Boyer
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Publication number: 20200146566Abstract: Aspects of the invention relates to systems and methods for monitoring an intravenous (IV) line functionality of an IV device. The system includes an IV catheter to be inserted into the vein of the living subject, at least one pressure sensor in fluid communication with the IV catheter to acquire peripheral venous signals; and a processing device. The processing device receives the peripheral venous signals from the pressure sensor, performs a spectral analysis on the peripheral venous signals to obtain a peripheral venous pressure frequency spectrum, and determines an IV line functionality of the IV catheter in real time, wherein the IV line functionality of the IV catheter indicates IV infiltration when amplitude decreases greater than a first threshold are detected from the peaks of the peripheral venous pressure frequency spectrum.Type: ApplicationFiled: January 13, 2020Publication date: May 14, 2020Inventors: Susan S. Eagle, Colleen Brophy, Kyle Mitchell Hocking, Franz Baudenbacher, Richard Boyer
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Patent number: 10531799Abstract: Aspects of the invention relates to systems and methods for monitoring an intravenous (IV) line functionality of an IV device. In one embodiment, the system includes an IV catheter to be inserted into the vein of the living subject, at least one pressure sensor in fluid communication with the IV catheter to acquire peripheral venous signals; and a processing device. The processing device receives the peripheral venous signals from the pressure sensor, performs a spectral analysis on the peripheral venous signals to obtain a peripheral venous pressure frequency spectrum, and then performs a statistical analysis on amplitudes of peaks of the peripheral venous pressure frequency spectrum to determine an IV line functionality of the IV catheter in real time. When the IV line functionality indicates IV infiltration, the processing device may control the fluid controlling device to stop the fluid flow from the fluid source to the IV catheter.Type: GrantFiled: February 3, 2016Date of Patent: January 14, 2020Assignee: VANDERBILT UNIVERSITYInventors: Susan S. Eagle, Colleen Brophy, Kyle Mitchell Hocking, Franz Baudenbacher, Richard Boyer
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Publication number: 20190343408Abstract: Devices, systems, and methods for monitoring patient hemodynamic status, systemic vascular resistance, reversal of cardiac and respiratory rates, and patient respiratory volume or effort are disclosed. A peripheral venous pressure is measured and used to detect levels, changes, or problems relating to patient blood volume. The peripheral venous pressure measurement is transformed from the time domain to the frequency domain for analysis. A heart rate frequency is identified, and harmonics of the heart rate frequency are detected and evaluated to determine, among other things, hypovolemia or hypervolemia, systemic vascular resistance, and of cardiac and respiratory rates, and patient respiratory volume or effort.Type: ApplicationFiled: August 22, 2018Publication date: November 14, 2019Inventors: Jonathan Handler, James Martucci, Kyle Hocking, Susan Eagle, Colleen Brophy, Richard Boyer, Franz Baudenbacher
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Patent number: 10456046Abstract: Aspects of the invention relates to systems and methods for detecting volume status, volume overload, dehydration, hemorrhage and real time assessment of resuscitation, as well as organ failure including but not limited cardiac, renal, and hepatic dysfunction, of a living subject using non-invasive vascular analysis (NIVA). In one embodiment, a non-invasive device, which includes at least one sensor, is used to acquire vascular signals from the living subject in real time. The vascular signals are sent to a controller, which processes the vascular signals to determine at least one hemodynamic parameter, such as the volume status of the living subject. In certain embodiments, the vascular signals are processed by a spectral fast Fourier transform (FFT) analysis to obtain the peripheral vascular signal frequency spectrum, and the volume status of the living subject may be determined by comparing amplitudes of the peaks of the peripheral vascular signal frequency spectrum.Type: GrantFiled: November 13, 2015Date of Patent: October 29, 2019Assignee: Vanderbilt UniversityInventors: Susan Eagle, Colleen Brophy, Kyle Hocking, Franz Baudenbacher, Richard Boyer
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Publication number: 20190183362Abstract: Devices, systems, and methods for filtering medical device noise artifacts from circulatory waveform signals are disclosed. A circulatory pressure is measured and transformed from the time domain to the frequency domain for analysis to determine patient status. To avoid artifacts of the pumping, the time-domain measurements are filtered to generate a filtered time-domain signal, by removing active pumping periods. The filtered time-domain signal is transformed into a frequency-domain signal, which is analyzed based upon peaks indicating respiratory rate, heart rate, or harmonics thereof. Peaks may be adjusted based on a ratio that considers removed signals. A metric of patient status is then determined from the peaks or corresponding frequencies. The patient status may be related to blood volume of the patient and may be used to control pump operation.Type: ApplicationFiled: December 14, 2018Publication date: June 20, 2019Inventors: Jonathan Handler, James Martucci, Kyle Hocking, Susan Eagle, Colleen Brophy, Richard Boyer, Franz Baudenbacher
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Patent number: 10179083Abstract: A compression device can include an adjustable belt, an inflation bladder, and a control module. The adjustable belt can be sized to fit circumferentially around a subject's abdomen. The inflatable bladder and the control module can be secured to the belt. The control module can include a housing that encloses at least one of a pump, a pressure relief valve, and a controller. The pump and the pressure relief valve can be in fluid communication with the bladder. The pump can be configured to inflate the bladder to a pre-determined pressure and apply a compressive pressure to the subject's abdomen. The pressure relief valve can be configured to decrease the pressure within the bladder. The controller can be configured to automatically adjust the compressive pressure in response to a change in the subject's posture. The controller can be in electrical communication with the pump and the pressure relief valve.Type: GrantFiled: November 4, 2013Date of Patent: January 15, 2019Assignee: Vanderbilt UniversityInventors: Franz Baudenbacher, Italo Biaggioni, Rene Harder, Andre Diedrich, Luis Okamoto
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Publication number: 20190000326Abstract: Devices, systems, and methods for filtering medical device noise artifacts from venous waveform signals are disclosed. A peripheral venous pressure (PVP) is measured and transformed from the time domain to the frequency domain for analysis to determine patient status. To avoid artifacts of the pumping, the time-domain PVP measurements are filtered to generate a filtered time-domain PVP signal by removing active pumping periods. The filtered time-domain PVP signal is transformed into a frequency-domain PVP signal, which is analyzed based upon peaks indicating respiratory rate, heart rate, or harmonics thereof. A metric of patient status is then determined from the peaks or corresponding frequencies. The patient status may be related to blood volume of the patient and may be used to control pump operation.Type: ApplicationFiled: June 29, 2018Publication date: January 3, 2019Inventors: Jonathan Handler, James Martucci, Kyle Hocking, Susan Eagle, Colleen Brophy, Richard Boyer, Franz Baudenbacher
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Patent number: 10082500Abstract: One aspect of the present disclosure relates to a calorimeter for detecting the presence of a target analyte in a fluid sample. The calorimeter can include a support structure, a hermetically-sealed, thermally decoupled central reaction zone associated with the support structure, at least one droplet transport region, and detection electronics. The at least one droplet transport region can be associated with the support structure and configured to merge a reagent droplet with a sample droplet including the fluid sample to form a reaction droplet in the central reaction zone. The detection electronics can be in electrical and/or thermal communication with the central reaction zone and associated with the support structure. The calorimeter can be configured to detect a heat of reaction produced by a reaction event between the target analyte and a capture reagent upon formation of the reaction droplet.Type: GrantFiled: February 19, 2015Date of Patent: September 25, 2018Inventors: Franz Baudenbacher, Raymond Mernaugh, John Mayo, Brad Lubbers, Robert G. Wiley
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Publication number: 20180168467Abstract: Devices, systems, and methods for monitoring patient hemodynamic status, systemic vascular resistance, reversal of cardiac and respiratory rates, and patient respiratory volume or effort are disclosed. A peripheral venous pressure is measured and used to detect levels, changes, or problems relating to patient blood volume. The peripheral venous pressure measurement is transformed from the time domain to the frequency domain for analysis. A heart rate frequency is identified, and harmonics of the heart rate frequency are detected and evaluated to determine, among other things, hypovolemia or hypervolemia, systemic vascular resistance, and of cardiac and respiratory rates, and patient respiratory volume or effort.Type: ApplicationFiled: December 15, 2017Publication date: June 21, 2018Inventors: Jonathan Handler, James Martucci, Kyle Hocking, Susan Eagle, Colleen Brophy, Richard Boyer, Franz Baudenbacher
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Publication number: 20180020935Abstract: Aspects of the invention relates to systems and methods for monitoring an intravenous (IV) line functionality of an IV device. In one embodiment, the system includes an IV catheter to be inserted into the vein of the living subject, at least one pressure sensor in fluid communication with the IV catheter to acquire peripheral venous signals; and a processing device. The processing device receives the peripheral venous signals from the pressure sensor, performs a spectral analysis on the peripheral venous signals to obtain a peripheral venous pressure frequency spectrum, and then performs a statistical analysis on amplitudes of peaks of the peripheral venous pressure frequency spectrum to determine an IV line functionality of the IV catheter in real time. When the IV line functionality indicates IV infiltration, the processing device may control the fluid controlling device to stop the fluid flow from the fluid source to the IV catheter.Type: ApplicationFiled: February 3, 2016Publication date: January 25, 2018Inventors: Susan S. Eagle, Colleen Brophy, Kyle Mitchell Hocking, Franz Baudenbacher, Richard Boyer
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Publication number: 20170332919Abstract: Aspects of the invention relates to systems and methods for detecting volume status, volume overload, dehydration, hemorrhage and real time assessment of resuscitation, as well as organ failure including but not limited cardiac, renal, and hepatic dysfunction, of a living subject using non-invasive vascular analysis (NIVA). In one embodiment, a non-invasive device, which includes at least one sensor, is used to acquire vascular signals from the living subject in real time. The vascular signals are sent to a controller, which processes the vascular signals to determine at least one hemodynamic parameter, such as the volume status of the living subject. In certain embodiments, the vascular signals are processed by a spectral fast Fourier transform (FFT) analysis to obtain the peripheral vascular signal frequency spectrum, and the volume status of the living subject may be determined by comparing amplitudes of the peaks of the peripheral vascular signal frequency spectrum.Type: ApplicationFiled: November 13, 2015Publication date: November 23, 2017Inventors: Susan Eagle, Colleen Brophy, Kyle Hocking, Franz Baudenbacher, Richard Boyer
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Publication number: 20160073959Abstract: Aspects of the invention relates to systems and methods for hypovolemia and/or hypervolemia detection of a living subject using peripheral intravenous waveform analysis. In one embodiment, the method includes: acquiring, from a vein of the living subject, peripheral venous signals; performing a spectral analysis on the acquired peripheral venous signals to obtain a peripheral venous pressure frequency spectrum; and performing a statistical analysis on amplitudes of peaks of the peripheral venous pressure frequency spectrum to determine the blood volume status of the living subject in real time. Specifically, at least two peaks, respectively corresponding to a first frequency and a second frequency, are obtained on the peripheral venous pressure frequency spectrum. Amplitude change of the second peak is used to determine the blood volume status of the living subject. Hemorrhage may be detected when a significant amplitude decrease is detected from the second baseline peak to the second peak.Type: ApplicationFiled: September 14, 2015Publication date: March 17, 2016Inventors: Susan Eagle, Colleen Brophy, Kyle Hocking, Franz Baudenbacher, Richard Boyer
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Publication number: 20150359489Abstract: One aspect of the present disclosure is a smart patient monitoring system. A sensor is coupled to a patient and configured to detect biometric data associated with the patient. A mobile computing device includes a memory that stores computer-executable instructions and a processor executes the computer-executable instructions. The mobile computing device receives the biometric data from the sensor; processes the biometric data to monitor a health status of the patient; and provides therapeutic feedback related to the health status.Type: ApplicationFiled: January 24, 2014Publication date: December 17, 2015Inventors: Franz Baudenbacher, Susan Eagle, Rene Harder, Jonathan Whitfield, Andre Diedrich, John B. Pietsch, Eric-Jan Manders