Patents by Inventor Franz Josef Kuhn

Franz Josef Kuhn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutically useful 3,4-dihydroisoquinoline
    Patent number: 6034094
    Abstract: The invention relates to the use of carbocyclically and heterocycally fused dihydroyridines as cerebroprotective agents, as agents for treating chronic inflammatory processes and as agents for inhabiting blood clotting, and also relates to new compounds of formula Ie ##STR1##
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: March 7, 2000
    Assignee: Boehringer Ingelheim KG
    Inventors: Walter Losel, Otto Roos, Dietrich Arndts, Franz Josef Kuhn, Ilse Strelle
  • Benzomorphan derivatives
    Patent number: 5731318
    Abstract: Novel benzomorphan derivatives of the formula ##STR1## wherein R.sup.1 -R.sup.8 are as defined herein. The benzomorphan derivatives are useful for treating cerebral ischaemia of various origins, epilepsy and neurodegenerative diseases.
    Type: Grant
    Filed: August 1, 1996
    Date of Patent: March 24, 1998
    Assignee: Boehringer Ingelheim KG
    Inventors: Adrian Carter, Helmut Ensinger, Matthias Grauert, Franz Josef Kuhn, Herbert Merz, Enzio Mueller, Werner Stransky, Ilse Streller
  • Asymmetrically substituted xanthines
    Patent number: 5719279
    Abstract: Xanthine derivatives of formula ##STR1## wherein R.sub.1 is hydrogen, alkyl or alkynyl,R.sub.2 is different and is alkyl, alkynyl, phenyl-alkylene, phenyl alkenylene, cycloalkyl, inter alia,R.sub.3 is cycloalkyl, phenyl, norbornane, inter alia andR.sub.4 is hydrogen, methyl, benzyl, inter alia.
    Type: Grant
    Filed: June 11, 1996
    Date of Patent: February 17, 1998
    Assignee: Boehringer Ingelheim KG
    Inventors: Ulrike Kufner-Muhl, Helmut Ensinger, Joachim Mierau, Franz Josef Kuhn, Erich Lehr, Enzio Muller
  • Xanthine derivatives with adenosine-antagonistic activity
    Patent number: 5696124
    Abstract: The invention relates to new xanthine derivatives of general formula I, processes for preparing them and their use as pharmaceutical compositions.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: December 9, 1997
    Assignee: Boehringer Ingelheim Kg
    Inventors: Ulrike Kufner-Muhl, Karl-Heinz Weber, Gerhard Waither, Werner Stransky, Helmut Ensinger, Gunter Schingnitz, Franz Josef Kuhn, Erich Lehr
  • Bornyl xanthine derivatives with adenosine-antagonistic activity
    Patent number: 5688802
    Abstract: The invention relates to new xanthine derivatives of general formula I, processes for preparing them and their use as pharmaceutical compositions.
    Type: Grant
    Filed: June 14, 1996
    Date of Patent: November 18, 1997
    Assignee: Boehringer Ingelheim KG
    Inventors: Ulrike Kufner-Muhl, Karl-Heinz Weber, Gerhard Walther, Werner Stransky, Helmut Ensinger, Gunter Schingnitz, Franz Josef Kuhn, Erich Lehr
  • Anti-inflammatory method
    Patent number: 5686462
    Abstract: The invention relates to the use of carbocyclically and heterocyclically fused dihydropyridines as cerebroprotective agents, as agents for treating chronic inflammatory processes and as agents for inhibiting blood clotting, and also relates to new compounds of formula Ie ##STR1##
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: November 11, 1997
    Assignee: Boehringer Ingelheim KG
    Inventors: Walter Losel, Otto Roos, Dietrich Arndts, Franz Josef Kuhn, Ilse Strelle
  • Cerebroprojection method
    Patent number: 5665729
    Abstract: The invention relates to the use of carbocyclically and heterocyclically fused dihydropyridines as cerebroprotective agents, as agents for treating chronic inflammatory processes and as agents for inhibiting blood clotting, and also relates to new compounds of formula Ie ##STR1##
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: September 9, 1997
    Assignee: Boehringer Ingelheim KG
    Inventors: Walter Losel, Otto Roos, Dietrich Arndts, Franz Josef Kuhn, Ilse Strelle
  • 8-substituted 1,3-dialiphaticxanthine derivatives
    Patent number: 5641784
    Abstract: New xanthine compounds of formula I: ##STR1## wherein the substituents are defined herein, which xanthines are useful as adenosine antagonists.
    Type: Grant
    Filed: December 22, 1994
    Date of Patent: June 24, 1997
    Assignee: Boehringer Ingelheim KG
    Inventors: Ulrike Kufner-Muhl, Werner Stransky, Gerhard Walther, deceased, Karl-Heinz Weber, Helmut Ensinger, Franz Josef Kuhn, Gunter Schingnitz, Erich Lehr
  • 1,2,4-triazolo-carbamates
    Patent number: 4732900
    Abstract: New 1,2,4-triazolo-carbamates of general formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have the meanings given in the specification, are acetylcholinesterase inhibitors and may be used as drugs for the treatment of senile dementia.
    Type: Grant
    Filed: October 25, 1985
    Date of Patent: March 22, 1988
    Assignee: Boehringer Ingelheim KG
    Inventors: Karl-Heinz Weber, Dieter Hinzen, Franz-Josef Kuhn, Erich Lehr, Wilhelm Frolke, Wolfgang Troger, Helmut Ensinger, Gerhard Walther, Albrecht Harreus
  • 1-Furyl-3,4-dihydro-isoquinolines
    Patent number: 4452789
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 and R.sub.2, which may be identical to or different from each other, are each hydroxyl or lower alkoxyR.sub.3 is cyano or --CO--Y;Y is hydroxyl, lower alkoxy, or a primary or secondary, substituted or unsubstituted, aliphatic, cycloaliphatic, araliphatic, aromatic or heterocyclic amino group;and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as the salts are useful for the treatment of circulatory and coronary disorders.
    Type: Grant
    Filed: October 25, 1982
    Date of Patent: June 5, 1984
    Assignee: Boehringer Ingelheim KG
    Inventors: Walter Losel, Otto Roos, Richard Reichl, Franz-Josef Kuhn
  • 6-Phenyl-8-bromo-4H-s-triazolo-[3,4C]-thieno-[2,3E]-1,4-diazepines and salts thereof
    Patent number: 4094984
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, fluorine, chlorine, bromine, nitro or trifluoromethyl; andR.sub.2 is hydrogen, alkyl of 1 to 4 carbon atoms or hydroxyalkyl of 1 to 4 carbon atoms; and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as tranquilizers, muscle-relaxants and anticonvulsants.
    Type: Grant
    Filed: October 6, 1977
    Date of Patent: June 13, 1978
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Karl-Heinz Weber, Adolf Bauer, Peter Danneberg, Franz Josef Kuhn
  • N-(3-(p-Fluoro -benzoyl)-n-propyl)-4-(imidazolidin-2-one-1-yl)-piperidines and salts thereof
    Patent number: 4087531
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, acetyl, alkyl of 1 to 3 carbon atoms or phenyl, and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as CNS-depressants, sedatives and tranquilizers.
    Type: Grant
    Filed: October 6, 1976
    Date of Patent: May 2, 1978
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Adolf Langbein, Gerhard Walther, Peter Danneberg, Franz Josef Kuhn
  • 2-(4-Phenyl-4-cyano-n-butyl)-1,2,3,4-tetrahydro-5(H)-pyri do-[4,3-b]-indoles and salts thereof
    Patent number: 4085216
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, halogen or methyl, andR.sub.2 is hydrogen, halogen, methyl or methoxy, and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as neuroleptics.
    Type: Grant
    Filed: May 9, 1977
    Date of Patent: April 18, 1978
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Adolf Langbein, Karl-Heinz Weber, Adolf Bauer, Karin Boke, Erich Lehr, Franz Josef Kuhn
  • N-(p-fluorobenzoyl-n-propyl)-4-piperidylamides and salts thereof
    Patent number: 4069331
    Abstract: Compounds of the formula ##STR1## wherein R is straight or branched alkyl of 1 to 4 carbon atoms, and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as sedatives and tranquilizers.
    Type: Grant
    Filed: January 17, 1977
    Date of Patent: January 17, 1978
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Adolf Langbein, Peter Danneberg, Franz Josef Kuhn
  • Propargyl-substituted 2-phenylamino-2-imidazolines and salts thereof
    Patent number: 4025607
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3, which may be identical to or different from each other, are each hydrogen, fluorine, chlorine, bromine, methyl, ethyl, methoxy or trifluoromethyl, andR.sub.4 and R.sub.5 are each hydrogen or propargyl, but other than both hydrogen or both propargyl at the same time,And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as the salts are useful as analgesics and hypotensives.
    Type: Grant
    Filed: May 17, 1976
    Date of Patent: May 24, 1977
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Helmut Stahle, Herbert Koppe, Werner Kummer, Klaus Stockhaus, Wolfgang Hoefke, Franz Josef Kuhn