Patents by Inventor Franz-Josef van der Staay

Franz-Josef van der Staay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110065730
    Abstract: The invention relates to novel 6-cyclylmethyl- and 6-alkylmethyl-substituted pyrazolopyrimidines, process for their preparation and their use for producing medicaments for improving perception, concentration, learning and/or memory.
    Type: Application
    Filed: November 19, 2010
    Publication date: March 17, 2011
    Inventors: Martin Hendrix, Lars Bärfacker, Christina Erb, Frank-Thorsten Hafner, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen, Franz-Josef van der Staay, Marja van Kampen
  • Publication number: 20100324085
    Abstract: The invention relates to novel benzothiophene-, benzofuran-, and indole ureas and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning, and/or memory.
    Type: Application
    Filed: August 30, 2010
    Publication date: December 23, 2010
    Applicant: Bayer Schering Pharma AG
    Inventors: Timo Flessner, Frank-Gerhard Böss, Christina Erb, Frank-Thorsten Hafner, Katrin Schnizler, Dieter Lang, Joachim Luithle, Maria-Van Kampen, Franz-Josef Van der Staay
  • Patent number: 7795453
    Abstract: The invention relates to novel benzothiophene-, benzofuran- and indole ureas and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.
    Type: Grant
    Filed: July 14, 2003
    Date of Patent: September 14, 2010
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Timo Fleβner, Frank-Gerhard Böβ, Christina Erb, Frank-Thorsten Hafner, Katrin Schnizler, Dieter Lang, Joachim Luithle, Marja Van Kampen, Franz-Josef Van der Staay
  • Publication number: 20100035900
    Abstract: The invention relates to novel 6-arylmethyl-substituted pyrazolopyrimidines, process for their preparation and their use for producing medicaments for improving perception, concentration, learning and/or memory.
    Type: Application
    Filed: October 16, 2009
    Publication date: February 11, 2010
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Martin HENDRIX, Lars Bärfacker, Christina Erb, Frank-Thorsten Hafner, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen, Franz-Josef van der Staay, Marja van Kampen
  • Patent number: 7615558
    Abstract: Described are 6-arylmethylpyrazolo[3,4-d]pyrimidines of the following formula: processes for their preparation and their use for producing medicaments for improving perception, concentration, learning and/or memory.
    Type: Grant
    Filed: April 27, 2004
    Date of Patent: November 10, 2009
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Martin Hendrix, Lars Bärfacker, Christina Erb, Frank-Thorsten Hafner, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen, Franz-Josef van der Staay, Marja van Kampen
  • Publication number: 20090111838
    Abstract: The invention relates to novel 6-arylamino-5-cyano-4-pyrimidinones of formula (I) methods for the production thereof, and the use thereof for producing medicaments utilized for improving awareness, concentration, learning capacity, and/or retentiveness of memory. Said compounds (I) show activity as PDE9 inhibitors.
    Type: Application
    Filed: December 19, 2008
    Publication date: April 30, 2009
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Martin HENDRIX, Lars BARFACKER, Bettina BEYREUTHER, Ulrich EBERT, Christina ERB, Frank-Thorsten HAFNER, Heike HECKROTH, Yan-Hong LIU, Dagmar KARTHAUS, Adrian TERSTEEGEN, Franz-Josef VAN DER STAAY, Marja VAN KAMPEN
  • Patent number: 7488733
    Abstract: The invention relates to novel 6-arylamino-5-cyano-4-pyrimidinones of formula (I) methods for the production thereof, and the use thereof for producing medicaments utilized for improving awareness, concentration, learning capacity, and/or retentiveness of memory. Said compounds (I) show activity as PDE9 inhibitors.
    Type: Grant
    Filed: June 16, 2004
    Date of Patent: February 10, 2009
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Martin Hendrix, Lars Bärfacker, Bettina Beyreuther, Ulrich Ebert, Christina Erb, Frank-Thorsten Hafner, Heike Heckroth, Yan-Hong Liu, Dagmar Karthaus, Adrian Tersteegen, Franz-Josef van der Staay, Marja van Kampen
  • Publication number: 20070161662
    Abstract: The invention relates to novel 6-arylmethyl-substituted pyrazolopyrimidines, process for their preparation and their use for producing medicaments for improving perception, concentration, learning and/or memory.
    Type: Application
    Filed: April 27, 2004
    Publication date: July 12, 2007
    Applicant: Bayer HealthCare AG
    Inventors: Martin Hendrix, Lars Barfacker, Christina Erb, Frank-Thorsten Hafner, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen, Franz-Josef van der Staay, Marja van Kampen
  • Publication number: 20070105881
    Abstract: The invention relates to novel 6-arylamino-5-cyano-4-pyrimidinones of formula (I) methods for the production thereof, and the use thereof for producing medicaments utilized for improving awareness, concentration, learning capacity, and/or retentiveness of memory. Said compounds (I) show activity as PDE9 inhibitors.
    Type: Application
    Filed: June 16, 2004
    Publication date: May 10, 2007
    Applicant: Bayer HealthCare AG
    Inventors: Martin Hendrix, Lars Barfacker, Bettina Beyreuther, Ulrich Ebert, Christina Erb, Frank-Thorsten Hafner, Heike Heckroth, Yan-Hong Liu, Dagmar Karthaus, Adrian Tersteegen, Franz-Josef van der Staay, Marja van Kampen
  • Publication number: 20070105876
    Abstract: The invention relates to novel 6-cyclylmethyl- and 6-alkylmethyl-substituted pyrazolopyrimidines, process for their preparation and their use for producing medicaments for improving perception, concentration, learning and/or memory.
    Type: Application
    Filed: April 28, 2004
    Publication date: May 10, 2007
    Inventors: Martin Hendrix, Lars Barfacker, Christina Erb, Frank-Thorsten Hafner, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen, Franz-Josef van der Staay, Marja van Kampen
  • Publication number: 20060106096
    Abstract: The invention relates to novel benzothiophene-, benzofuran- and indole ureas and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.
    Type: Application
    Filed: July 14, 2003
    Publication date: May 18, 2006
    Applicant: BAYER HEALTH AG
    Inventors: Timo Flessner, Frank-Gerhard Bossw, Christina Erb, Frank-Thorsten Hafner, Katrin Schnizler, Dieter Lang, Joachim Luithle, Marja Van Kampen, Franz-Josef Van der Staay
  • Patent number: 7022709
    Abstract: The invention relates to the use of selective phosphodiesterase 2 (PDE 2) inhibitors for producing pharmaceuticals for improving perception, concentration, learning and/or memory.
    Type: Grant
    Filed: July 23, 2001
    Date of Patent: April 4, 2006
    Inventors: Frank-Gerhard Böss, Martin Hendrix, Gerhard König, Ulrich Niewöhner, Karl-Heinz Schlemmer, Rudy Schreiber, Franz-Josef Van Der Staay, Dagmar Schauss
  • Patent number: 6998402
    Abstract: The invention relates to novel substituted imidazotriazinones, to a method for their production and to the use thereof for producing medicaments, in particular to improve perception, powers of concentration, learning capacity and/or memory retentiveness.
    Type: Grant
    Filed: February 11, 2002
    Date of Patent: February 14, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Maria Theresia Niewöhner, legal representative, Dagmar Schauss, Gerhard König, Martin Hendrix, Frank-Gerhard Böss, Franz-Josef van der Staay, Rudy Schreiber, Karl-Heinz Schlemmer, Toshiya Moriwaki, Ulrich Niewöhner, deceased
  • Publication number: 20040152700
    Abstract: The present invention relates to the use of PDE 5 inhibitors generally and in particular of 2-phenyl-substituted imidazotriazinones for the production of a medicament for improving the perception, concentration power, learning power and/or memory power, in particular for the treatment and/or prophylaxis of disorders of the perception, concentration power, learning power and/or memory power.
    Type: Application
    Filed: April 8, 2004
    Publication date: August 5, 2004
    Inventors: Ulrich Niewohner, Maria Theresia Niewohner, Erwin Bischoff, Helmut Haning, Afssaneh Rahbar, Tiemo-Jorg Bandel, Wolfgang Barth, Franz-Josef Van Der Staay
  • Patent number: 6589949
    Abstract: The invention relates to novel 3-oxo-2,1-benzisomazol-1(3H)-carboxamides (I), where R1, R2 are the same or different and independently=H, halogen, C1 C6 alkyl C1 C6 alkoxy, C1 C3 perfluoroalkyl, or a group NR5R6; R3, R4 are the same or different and independently=C1 C8 alkyl, whose carbon chain is optionally interrupted by an O, S or NR7 and is optionally singly or severally substituted by C3 C6 cycloalkyl, C1 C4 alkoxy, OH, halogen or NR8R9; C3 C8 cycloalkyl whose carbon chain is optionally interrupted by an O, S or NR10 and is optionally singly or severally substituted by C1 C4 alkoxy, OH, halogen or NR11R12, or R3 and R4 together with a nitrogen atom form a saturated or partially unsaturated 3- to 10-membered mono- or bi-cyclic heteocycle, which, optionally, contains up to two further heteroatoms, from N, O or S and is, optionally, substituted by C1 C4 alkyl, C1 C4 alkoxy, OH, halogen, COOR13 or NR14R15 and X=O or S.
    Type: Grant
    Filed: October 22, 2002
    Date of Patent: July 8, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Toshiya Moriwaki, Chantal Fürstner, Bernd Riedl, Jens-Kerim Ergüden, Frank Böss, Bernard Schmidt, Franz-Josef van der Staay, Werner Schröder, Karl-Heinz Schlemmer, Nagahiro Yoshida
  • Patent number: 6573263
    Abstract: The present invention relates to new substituted imidazotriazinones, processes for their preparation, and their use for the production of medicaments, in particular for improving perception, concentration power, learning power and/or memory power.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: June 3, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ulrich Niewöhner, Dagmar Schauss, Martin Hendrix, Gerhard König, Frank-Gerhard Böss, Franz-Josef Van Der Staay, Rudy Schreiber, Karl-Heinz Schlemmer, Rolf Grosser
  • Publication number: 20020198377
    Abstract: The present invention relates to new substituted imidazotriazinones, processes for their preparation, and their use for the production of medicaments, in particular for improving perception, concentration power, learning power and/or memory power.
    Type: Application
    Filed: December 21, 2001
    Publication date: December 26, 2002
    Inventors: Ulrich Niewohner, Dagmar Schauss, Martin Hendrix, Gerhard Konig, Frank-Gerhard Boss, Franz-Josef Van Der Staay, Rudy Schreiber, Karl-Heinz Schlemmer, Rolf Grosser
  • Publication number: 20020132754
    Abstract: The invention relates to the use of selective phosphodiesterase 2 (PDE 2) inhibitors for producing pharmaceuticals for improving perception, concentration, learning and/or memory.
    Type: Application
    Filed: July 23, 2001
    Publication date: September 19, 2002
    Inventors: Frank-Gerhard Boss, Martin Hendrix, Gerhard Konig, Ulrich Niewohner, Karl-Heinz Schlemmer, Rudy Schreiber, Franz-Josef Van Der Staay, Dagmar Schauss
  • Patent number: 6344471
    Abstract: The present invention relates to novel 2-aminocarbonyl-5(2H)-isoxazolones as selective ligands of a high-affinity binding site of diisopropyl fluorophosphate (DFP) on brain membranes for the prophylaxis and treatment of disorders of the central nervous system, in particular cognitive disorders, depression, schizophrenia and anxiety.
    Type: Grant
    Filed: February 27, 2001
    Date of Patent: February 5, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventors: Stephan Lensky, Bernd Riedl, Chantal Fürstner, Jens Ergüden, Frank Böss, Bernhard Schmidt, Franz-Josef van der Staay, Werner Schröder, Joachim Schuhmacher, Delf Schmidt
  • Patent number: 6174897
    Abstract: The present invention relates to bis-(quinolyl)-diamines of the general formula (I): in which the indicated substituents are as defined in the description. The invention also provides a process for the preparation of the compounds of the formula (I), their use for the preparation of drugs, and drugs containing said compounds.
    Type: Grant
    Filed: October 25, 1996
    Date of Patent: January 16, 2001
    Assignee: Bayer Aktiengesellschaft
    Inventors: Rudolf Schohe-Loop, Peter-Rudolf Seidel, William Bullock, Achim Feurer, Georg Terstappen, Joachim Schuhmacher, Franz-Josef van der Staay, Bernard Schmidt, Richard J. Fanelli, Jane C. Chisholm, Richard T. McCarthy