Patents by Inventor Franz Kaufmann
Franz Kaufmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8859235Abstract: A method for the manufacture of products by biotechnological methods in bacterial cell culture is disclosed as well as products obtained, the use of certain additives to the media used in the manufacture of said products in bacterial cell culture media, and the use of said additives in reducing the detrimental effects of radicals in the manufacture of the products, as well as aspects related to these invention embodiments. The manufacturing process or method comprises adding one or more radical scavenging and/or antioxidative additive preferably selected from the group consisting of sterically hindered nitroxyls, sterically hindered hydroxylamines, sterically hindered hydroxylamine salt compounds, sterically hindered amino compounds and sterically hindered N-hydrocarbyloxyamines, benzofuranone compounds, as obligatory component(s) to the medium used during biosynthesis.Type: GrantFiled: August 11, 2010Date of Patent: October 14, 2014Assignee: BASF SEInventors: Franz Kaufmann, Trine Hefsgaard Miller, Johannes Flothmann, Beate Winter, Andreas Hafner
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Patent number: 8785142Abstract: The invention relates to an arrangement, comprising a solid carrier and a matrix arranged on the solid carrier, said matrix comprising at least one enzymatically convertible or modifiable molecule and comprising at least one enzyme that can be released by the conversion or modification of the molecule, said enzyme being capable of converting at least one color-changing substrate located in the matrix and/or on the solid carrier.Type: GrantFiled: February 9, 2011Date of Patent: July 22, 2014Inventors: Georg Gübitz, Eva Sigl, Andrea Hasmann, Marc Schröder, Konstantin Schneider, Alexandra Rollett, Franz Kaufmann, Andreas Hafner
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Patent number: 8758730Abstract: The present invention provides the use of surface active proteins, especially class I and class II hydrophobins, in topically applied pharmaceutical formulations. The invention is particularly directed to topically applied pharmaceutical products for enhancing the penetration to achieve a transungual delivery of a prophylactically and/or therapeutically effective amount of an active ingredient (drug) to a patient (including animals and humans) into and/or through a nail, of the animal or human body, in order to treat one or more of a variety of diseases or disorders. Related embodiments of the invention are also disclosed.Type: GrantFiled: February 19, 2010Date of Patent: June 24, 2014Assignee: B.R.A.I.N. Biotechnology Research and Information Network AGInventors: Andreas Buthe, Andreas Hafner, Franz Kaufmann, Babette Fiedler, Guido Meurer, Gordon Bradley
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Patent number: 8455107Abstract: By treatment with hydrophobins, cellulosic materials such as paper, cardboard, cotton or, especially, wood-based materials, such as solid wood, glued wood products or particle board, can be effectively protected against absorption of and attack by water and/or moisture.Type: GrantFiled: February 27, 2008Date of Patent: June 4, 2013Assignee: BASF SEInventors: Esther Gabor, Andreas Buthe, Jürgen Eck, Franz Kaufmann, Hans-Jörg Koch, Guido Meurer
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Publication number: 20120309036Abstract: The invention relates to an arrangement, comprising a solid carrier and a matrix arranged on the solid carrier, said matrix comprising at least one enzymatically convertible or modifiable molecule and comprising at least one enzyme that can be released by the conversion or modification of the molecule, said enzyme being capable of converting at least one color-changing substrate located in the matrix and/or on the solid carrier.Type: ApplicationFiled: February 9, 2011Publication date: December 6, 2012Inventors: Georg Gübitz, Eva Sigl, Andrea Hasmann, Marc Schröder, Konstantin Schneider, Alexandra Rollett, Franz Kaufmann, Andreas Hafner
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Patent number: 8226967Abstract: The invention relates to a use of surface active hydrophobins for applications in pharmaceutical technology, in particular as excipients for galenic use. Provided is a method for either admixture of hydrophobins to galenic compositions or for treating the surface of pharmaceutical forms with a hydrophobin-containing solution to modify the pharmaceutical properties of the galenic form. In a preferred embodiment of the invention hydrophobins are used to improve the properties of a pharmaceutical composition, e.g. to act as a surfactant or to increase resistance to disintegration of the galenic forms to achieve a retarded drug release. The galenic form to be modified by the use of surface active proteins as excipients can be capsules, tablets, pills, microparticles, vesicles, and suppositories, although further galenic forms are envisioned.Type: GrantFiled: November 13, 2009Date of Patent: July 24, 2012Assignee: BASF SEInventors: Andreas Buthe, Andreas Hafner, Franz Kaufmann, Esther Gabor, Guido Meurer, Jürgen Eck, Gordon Bradley
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Publication number: 20120164162Abstract: A method for the manufacture of products by biotechnological methods in bacterial cell culture is disclosed as well as products obtained, the use of certain additives to the media used in the manufacture of said products in bacterial cell culture media, and the use of said additives in reducing the detrimental effects of radicals in the manufacture of the products, as well as aspects related to these invention embodiments. The manufacturing process or method comprises adding one or more radical scavenging and/or antioxidative additive preferably selected from the group consisting of sterically hindered nitroxyls, sterically hindered hydroxylamines, sterically hindered hydroxylamine salt compounds, sterically hindered amino compounds and sterically hindered N-hydrocarbyloxyamines, benzofuranone compounds, as obligatory component(s) to the medium used during biosynthesis.Type: ApplicationFiled: August 11, 2010Publication date: June 28, 2012Applicant: BASF SEInventors: Franz Kaufmann, Trine Hefsgaard Miller, Johannes Flothmann, Beate Winter, Andreas Hafner
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Publication number: 20120058199Abstract: The present invention provides the use of surface active proteins, especially class I and class II hydrophobins, in topically applied pharmaceutical formulations. The invention is particularly directed to topically applied pharmaceutical products for enhancing the penetration to achieve a transungual delivery of a prophylactically and/or therapeutically effective amount of an active ingredient (drug) to a patient (including animals and humans) into and/or through a nail, of the animal or human body, in order to treat one or more of a variety of diseases or disorders. Related embodiments of the invention are also disclosed.Type: ApplicationFiled: February 19, 2010Publication date: March 8, 2012Applicant: BASF SEInventors: Andreas Buthe, Andreas Hafner, Franz Kaufmann, Babette Fiedler, Guido Meurer, Gordon Bradley
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Publication number: 20110268792Abstract: The invention relates to a use of surface active hydrophobins for applications in pharmaceutical technology, in particular as excipients for galenic use. Provided is a method for either admixture of hydrophobins to galenic compositions or for treating the surface of pharmaceutical forms with a hydrophobin-containing solution to modify the pharmaceutical properties of the galenic form. In a preferred embodiment of the invention hydrophobins are used to improve the properties of a pharmaceutical composition, e.g. to act as a surfactant or to increase resistance to disintegration of the galenic forms to achieve a retarded drug release. The galenic form to be modified by the use of surface active proteins as excipients can be capsules, tablets, pills, microparticles, vesicles, and suppositories, although further galenic forms are envisioned.Type: ApplicationFiled: November 13, 2009Publication date: November 3, 2011Applicant: BASF SEInventors: Andreas Buthe, Andreas Hafner, Franz Kaufmann, Esther Gabor, Guido Meurer, Jürgen Eck, Gordon Bradley
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Publication number: 20110159050Abstract: Disclosed is a process for modifying the morphology and/or polymorphism of an organic substance, which process comprises treating the solid substance, or a solution or dispersion thereof, with one or more amphiphilic proteins.Type: ApplicationFiled: June 23, 2009Publication date: June 30, 2011Applicant: BASF SEInventors: Andreas Hafner, Andreas Buthe, Paul Adriaan Van Der Schaaf, Franz Kaufmann, Gordon Bradley
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Publication number: 20100330384Abstract: By treatment with hydrophobins, cellulosic materials such as paper, cardboard, cotton or, especially, wood-based materials, such as solid wood, glued wood products or particle board, can be effectively protected against absorption of and attack by water and/or moisture.Type: ApplicationFiled: February 27, 2008Publication date: December 30, 2010Applicant: CIBA CORPORATIONInventors: Esther Gabor, Andreas Buthe, Jurgen Eck, Franz Kaufmann, Hans-Jorg Koch, Guido Meurer
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Patent number: 5302727Abstract: Compounds of the formula ##STR1## wherein R is a residue of the formula ##STR2## and R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, X, Y and Z are as described, with the exception of rac-N-(3,4-dimethoxyphenethyl)-2-(3,4-dimethoxyphenyl)-.beta.,N-dimethyl-m -dithiane-2-propanamine, as well as their acid addition salts, in particular for use in eliminating cytostatic resistance in tumor treatment and chloroquine resistance in malaria.Type: GrantFiled: July 15, 1992Date of Patent: April 12, 1994Assignee: Hoffmann-La Roche Inc.Inventors: James F. Eliason, Henri Ramuz, Franz A. Kaufmann-Schmid, deceased