Patents by Inventor Franz Schwarzenbach
Franz Schwarzenbach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20100252820Abstract: Electroneutral metal complexes of the formula L Cu A, wherein L stands for an, especially bidentate, neutral ligand and A stands for an, especially bidentate, monoanionic ligand binding to Cu by at least one heteroatom selected from N, P, S; or wherein the ligands L and A with the above features are interconnected by at least one chemical bond to form one common tetradentate ligand; or protonated or alkylated forms or salts thereof show good light emitting efficiency in electroluminescent applications.Type: ApplicationFiled: June 13, 2008Publication date: October 7, 2010Applicant: CIBA CORPORATIONInventors: Luisa De Cola, Yinghui Sun, Franz Schwarzenbach, Roger Pretot
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Patent number: 7442838Abstract: Sertraline hydrochloride polymorphic form II is conveniently prepared by adding hydrogen chloride to solution of sertraline free amine in a ketone. In preferred processes, the solution of sertraline free amine seeded with some crystals of polymorphic form II and/or the solution is heated before addition of the hydrogen chloride.Type: GrantFiled: April 8, 2005Date of Patent: October 28, 2008Assignee: Ciba Specialty Chemicals Corp.Inventors: Paul Adriaan Van Der Schaaf, Franz Schwarzenbach, Hans Jürg Kirner, Martin Szelagiewicz, Claudia Marcolli, Andreas Burkhard
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Patent number: 7402675Abstract: An amine ether of formula A wherein a is 1 or 2; and when a is 1, E is E?; when a is 2, E is L; E? is C1-C36 alkyl; C3-C18 alkenyl; C2-C18 alkinyl; C5-C18 cycloalkyl; C5-C18 cycloalkenyl; a radical of a saturated or unsaturated aliphatic bicyclic or tricyclic hydrocarbon of 7 to 12 carbon atoms; C2-C7alkyl or C3-C7alkenyl substituted by halogen; C7-C15 aralkyl or C7-C15 aralkyl substituted by C1-C4 alkyl or phenyl; or E? is a radical of formula (VII) as explained in claim 1; T? is tertiary C4-C18alkyl or phenyl, each of which are unsubstituted or substituted by halogen, OH, COOR21 or C(O)—R22; or T? is C5-C12cycloalkyl; C5-C12cycloalkyl which is interrupted by at least one O or —NR18—; a polycyclic alkyl radical having 7-18 carbon atoms, or the same radical which is interrupted by at least one O or —NR18—; or T? is —C(G1)(G2)-T?; or C1-C18alkyl or C5-C12cycloalkyl substituted by T? is hydrogen, halogen, NO2, cyano, or is a monovalent organic radical comprising 1-50 carbon atoms; or T? and T?Type: GrantFiled: August 17, 2004Date of Patent: July 22, 2008Assignee: Ciba Specialty Chemicals Corp.Inventors: Andreas Hafner, Hans Jürg Kirner, Franz Schwarzenbach, Paul Adriaan Van Der Schaaf, Peter Nesvadba
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Publication number: 20050197404Abstract: Sertraline hydrochloride polymorphic form II is conveniently prepared by adding hydrogen chloride to solution of sertraline free amine in a ketone. In preferred processes, the solution of sertraline free amine seeded with some crystals of polymorphic form II and/or the solution is heated before addition of the hydrogen chloride.Type: ApplicationFiled: April 8, 2005Publication date: September 8, 2005Inventors: Paul Van Der Schaaf, Franz Schwarzenbach, Hans Kirner, Martin Szelagiewicz, Claudia Marcolli, Andreas Burkhard
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Patent number: 6939992Abstract: A crystalline form of sertraline hydrochloride was found, referred to hereinafter as polymorphic form CSC2 having a dissolution rate which surprisingly will increase rate of absorption of a drug. Furthermore, different crystalline forms of sertraline hydrochloride alcohol solvates, crystalline forms of sertraline hydrochloride hydrates, referred to hereinafter as polymorphic form CSC1, a process for the preparation of the amorphous form of sertraline hydrochloride, and different processes for the preparation of polymorphic forms I, II, V, and T1 are disclosed.Type: GrantFiled: December 15, 2003Date of Patent: September 6, 2005Assignee: Ciba Specialty Chemicals CorporationInventors: Paul Adriaan Van Der Schaaf, Franz Schwarzenbach, Hans-Jörg Kirner, Martin Szelagiewicz, Claudia Marcolli, Andreas Burkhard
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Publication number: 20050119351Abstract: An improved process for the preparation of sertraline hydrochloride polymorphic form II is described, which process comprises seeding a solution of sertraline free amine in a ketone with some crystals of polymorphic form II and addition of hydrogen chloride, and wherein the solution is heated before addition of the hydrogen chloride. According to the present process, the metastable form II may be obtained in a reliable way with good yield and high purity with respect to other polymorphic forms as well as preparative residues such as educts or solvents.Type: ApplicationFiled: September 21, 2004Publication date: June 2, 2005Inventors: Paul Van Der Schaaf, Franz Schwarzenbach, Hans-Jorg Kirner, Martin Szelagiewicz, Claudia Marcolli, Andreas Burkhard
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Patent number: 6900328Abstract: An amine ether of formula (A) wherein a is 1 or 2; and when a is 1, E is E?; when a is 2, E is L; E? is C1-C36 alkyl; C3-C18 alkenyl; C2-C18 alkinyl; C5-C18 cycloalkyl; C5-C18 cycloalkenyl; a radical of a saturated or unsaturated aliphatic bicyclic or tricyclic hydrocarbon of 7 to 12 carbon atoms; C2-C7alkyl or C3-C7alkenyl substituted by halogen; C7-C15aralkyl or C7-C15 aralkyl substituted by C1-C4 alkyl or phenyl; or E? is a radical of formula (VII) as explained in claim 1; T? is tertiary C4-C18alkyl or phenyl, each of which are unsubstituted or substituted by halogen, OH, COOR21 or C(O)—R22; or T? is C5-C12cycloalkyl; C5-C12cacloalkyl which is interrupted by at least one O or —NR18—; a polycyclic alkyl radical having 7-18 carbon atoms, or the same radical which is interrupted by at least one O or —NR18—; or T? is —C(G1)(G2)—T?; or C1-C18alkyl or C5-C12cycloalkyl substituted by F(I)T? is hydrogen, halogen, NO2, cyano, or is a monovalent organic radical comprising 1-50 carbon atoms; or T? and T? together forType: GrantFiled: May 17, 2001Date of Patent: May 31, 2005Assignee: Ciba Specialty Chemicals CorporationInventors: Andreas Hafner, Hans Jürg Kirner, Franz Schwarzenbach, Paul Adriaan Van Der Schaaf, Peter Nesvadba
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Patent number: 6872853Abstract: A cystalline form of sertraline hydrochloride was found, referred to hereinafter as polymorphic form CSC2 having a dissolution rate which surprisingly will increase rate of absorption of a drug. Furthermore, different crystalline forms of sertraline hydrochloride alcohol solvates, crystalline forms of sertraline hydrochloride hydrates, referred to hereinafter as polymorphic form CSC1, a process for the preparation of the amorphous form of sertraline hydrochloride, and different processes for the preparation of polymorphic forms I, II, V, and T1 are disclosed.Type: GrantFiled: October 23, 2000Date of Patent: March 29, 2005Assignee: Ciba Specialty Chemicals CorporationInventors: Paul Adriaan Van Der Schaaf, Franz Schwarzenbach, Hans-Jörg Kirner, Martin Szelagiewicz, Claudia Marcolli, Andreas Burkhard, Regine Peter
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Publication number: 20050043552Abstract: An amine ether of formula A wherein a is 1 or 2; and when a is 1, E is E?; when a is 2, E is L; E? is C1-C36 alkyl; C3-C18 alkenyl; C2-C18 alkinyl; C5-C18 cydoalkyl; C5-C18 cycloalkenyl; a radical of a saturated or unsaturated aliphatic bicyclic or tricyclic hydrocarbon of 7 to 12 carbon atoms; C2-C7alkyl or C3-C7alkenyl substituted by halogen; C7-C15 aralkyl or C7-C15 aralkyl substituted by C1-C4 alkyl or phenyl; or E? is a radical of formula (VII) as explained in claim 1; T? is tertiary C4-C18alkyl or phenyl, each of which are unsubstituted or substituted by halogen, OH, COOR21 or C(O)—R22; or T? is C5-C12cycloalkyl; C5-C12 cycloalkyl which is interrupted by at least one O or —NR18—; a polycyclic alkyl radical having 7-18 carbon atoms, or the same radical which is interrupted by at least one O or —NR18—; or T? is —C(G1)(G2)—T?; or C1-C18alkyl or C5-C12cycloalkyl substituted by T? is hydrogen, halogen, NO2, cyano, or is a monovalent organic radical comprising 1-50 carbon atoms; or T? and T? togeType: ApplicationFiled: August 17, 2004Publication date: February 24, 2005Inventors: Andreas Hafner, Hans Kirner, Franz Schwarzenbach, Paul Van Der Schaaf, Peter Nesvadba
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Publication number: 20040132828Abstract: A crystalline form of sertraline hydrochloride was found, referred to hereinafter as polymorphic form CSC2 having a dissolution rate which surprisingly will increase rate of absorption of a drug.Type: ApplicationFiled: December 15, 2003Publication date: July 8, 2004Inventors: Paul Adriaan Van Der Schaaf, Franz Schwarzenbach, Hans-Jorg Kirner, Martin Szelagiewicz, Claudia Marcolli, Andreas Burkhard, Regine Peter
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Publication number: 20030171461Abstract: An amine ether of formula (A) wherein a is 1 or 2; and when a is 1, E is E′; when a is 2, E is L; E′ is C1-C36 alkyl; C3-C18 alkenyl; C2-C18 alkinyl; C5-C18 cycloalkyl; C5-C18 cycloalkenyl; a radical of a saturated or unsaturated aliphatic bicyclic or bricyclic hydrocarbon of 7 to 12 carbon atoms; C2-C7alkyl or C3-C7alkenyl substituted by halogen; C7-C15aralkyl or C7-C15 aralkyl substituted by C1-C4 alkyl or phenyl; or E′ is a radical of formula (VII) as explained in claim 1; T′ is tertiary C4-C18alkyl or phenyl, each of which are unsubstituted or substituted by halogen, OH, COOR21 or C(O)—R22; or T′ is C5-C12cycloalkyl; C5-C12cacloalkyl which is interrupted by at least one O or —NR18—; a polycyclic alkyl radical having 7-18 carbon atoms, or the same radical which is interrupted by at least one O or —NR18—; or T′ is —C(G1)(G2)—T″; or C1-C18alkyl or C5-C12cycloalkyl substituted by F(I)T″ is hydrogen, halogen, NO2, cyano,Type: ApplicationFiled: November 22, 2002Publication date: September 11, 2003Inventors: Andreas Hafner, Hans Jurg Kirner, Franz Schwarzenbach, Paul Adriaan Van Der Schaaf, Peter Nesvadba
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Patent number: 5073476Abstract: Iron (II)-aromatic compound complexes mixed with electron acceptors as an oxidizing agent are suitable initiators for the polymerization by irradiation of organic material which can be polymerized by cations and/or free radicals. The composition composed of the polymerizable material and of the initiator mixture is suitable for the production of protective coatings and can be used as a photographic recording material.Type: GrantFiled: May 10, 1984Date of Patent: December 17, 1991Assignee: Ciba-Geigy CorporationInventors: Kurt Meier, Giuliano Eugster, Franz Schwarzenbach, Hans Zweifel