Patents by Inventor Franz X. Heinz

Franz X. Heinz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the detection of an IgM antibody specific for a flavivirus in a sample
    Patent number: 10591480
    Abstract: Disclosed is a method for the detection of an IgM antibody specific for a flavivirus in a sample, comprising the steps of (a) contacting the sample with a solid support comprising immobilised IgM-binding molecules, (b) allowing binding of IgM antibodies in the sample to the IgM binding molecules on the solid support so that the IgM antibodies are also immobilised on the solid support, and (c) detecting IgM antibodies specific for a flavivirus by allowing binding of a complex comprising (i) an antiparallel dimer of soluble flavivirus Protein E (sE) and (ii) a marker and identifying the binding of the complex to the specific flavivirus IgM antibody by detecting the marker; and a kit suitable for performing the method.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: March 17, 2020
    Assignee: MEDIZINISCHE UNIVERSITÄT WIEN
    Inventors: Franz X. Heinz, Karin Stiasny
  • Method for the Detection of an IgM Antibody Specific for a Flavivirus in a Sample
    Publication number: 20190170750
    Abstract: Disclosed is a method for the detection of an IgM antibody specific for a flavivirus in a sample, comprising the steps of (a) contacting the sample with a solid support comprising immobilised IgM-binding molecules, (b) allowing binding of IgM antibodies in the sample to the IgM binding molecules on the solid support so that the IgM antibodies are also immobilised on the solid support, and (c) detecting IgM antibodies specific for a flavivirus by allowing binding of a complex comprising (i) an antiparallel dimer of soluble flavivirus Protein E (sE) and (ii) a marker and identifying the binding of the complex to the specific flavivirus IgM antibody by detecting the marker; and a kit suitable for performing the method.
    Type: Application
    Filed: June 2, 2017
    Publication date: June 6, 2019
    Inventors: Franz X. HEINZ, Karin STIASNY
  • Flaviviridae mutants comprising a deletion in the capsid protein for use as vaccines
    Patent number: 8715999
    Abstract: The present invention relates to a mutant virus of the family flaviviridae, comprising a deletion in the capsid protein of at least 20 successive amino acids, without any further deletion, substitution or insertion mutation except of the amino acids next to the deletion, which may be substituted.
    Type: Grant
    Filed: February 6, 2009
    Date of Patent: May 6, 2014
    Assignee: Valneva Austria GmbH
    Inventors: Franz X. Heinz, Christian Mandl, Petra Schlick, Andreas Meinke
  • Flaviviridae Mutants Comprising a Deletion in the Capsid Protein for Use as Vaccines
    Publication number: 20100323003
    Abstract: The present invention relates to a mutant virus of the family flaviviridae, comprising a deletion in the capsid protein of at least 20 successive amino acids, without any further deletion, substitution or insertion mutation except of the amino acids next to the deletion, which may be substituted.
    Type: Application
    Filed: February 6, 2009
    Publication date: December 23, 2010
    Applicant: INTERCELL AG
    Inventors: Franz X. Heinz, Christian Mandl, Petra Schlick, Andreas Meinke