Patents by Inventor Franzanne Vreeland

Franzanne Vreeland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antitumor therapy comprising distamycin derivatives
    Patent number: 7399748
    Abstract: The present invention relates to an administration schedule comprising the intravenous administration of a ?-halogen-acryloyl distamycin derivative, or a pharmaceutically acceptable salt thereof. The above administration allows the treatment of a variety of tumors in mammals.
    Type: Grant
    Filed: September 21, 2001
    Date of Patent: July 15, 2008
    Assignee: Nerviano Medical Sciences S.r.l.
    Inventors: Camilla Fowst, Franzanne Vreeland, Maria Cristina Rosa Geroni
  • Salts, Prodrugs and Formulations of 1-[5-(4-Amino-7-Isopropyl-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carbonyl)-2-Methoxy-Phenyl]-3-(2,4-Dichloro-Phenyl)-Urea
    Publication number: 20070287719
    Abstract: The invention relates to compounds of the formula or a pharmaceutically acceptable salt, prodrug or hydrates thereof. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula 1.
    Type: Application
    Filed: December 8, 2006
    Publication date: December 13, 2007
    Inventors: Tracy Boyden, Susan La Greca, Feng Guo, Douglas Lorenz, Ravi Shanker, Franzanne Vreeland
  • Method for predicting the sensitivity to chemotherapy
    Patent number: 6969592
    Abstract: The present invention relates to the field of cancer treatment and, more particularly, it relates to a method for predicting the sensitivity towards chemotherapy of a patient, by measuring glutathione (GSH) blood levels of the said patient undergoing chemotherapeutic treatment.
    Type: Grant
    Filed: September 26, 2001
    Date of Patent: November 29, 2005
    Assignees: Pharmacia Italia S.p.A., Pharmacia & Upjohn Company LLC
    Inventors: Camilla Fowst, Maria Christina Rosa Geroni, Jennifer Margaret Tursi, Franzanne Vreeland
  • Antitumor therapy comprising distamycin derivatives
    Patent number: 6576612
    Abstract: The present invention relates to an administration schedule comprising the intravenous administration of a &agr;-halogen-acryloyl distamycin derivative of formula (I) wherein R is a bromine or chlorine atom; or a pharmaceutically acceptable salt thereof. The above administration allows the treatment of a variety of tumors in mammals.
    Type: Grant
    Filed: October 2, 2000
    Date of Patent: June 10, 2003
    Assignees: Pharmacia Italia S.p.A., Pharmacia & Upjohn Company
    Inventors: Camilla Fowst, Franzanne Vreeland, Maria Cristina Rosa Geroni
  • Method for predicting the sensitivity to chemotherapy
    Publication number: 20030096325
    Abstract: Herewith described is a novel method for predicting the sensitivity towards chemotherapy, of a patient in need thereof, which comprises obtaining a blood sample from the patient and detecting the levels of blood glutathione (GSH) as a surrogate marker for glutathione-S-transferase (GST) activity in tumor tissues.
    Type: Application
    Filed: September 26, 2001
    Publication date: May 22, 2003
    Inventors: Camilla Fowst, Maria Christina Rosa Geroni, Jennifer Margaret Tursi, Franzanne Vreeland