Patents by Inventor Fraser Aird

Fraser Aird has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods useful for treatment of depressive disorder based on an animal model
    Publication number: 20020138856
    Abstract: The invention includes WKY rats which are selectively bred based on more depressed (WMI) or less depressed (WLI) behavior. The invention also includes methods of using the rats for diagnosis and treatment of behavioral disorders and further includes compositions based on the genotype differences between WMI and WLI rats.
    Type: Application
    Filed: December 17, 2001
    Publication date: September 26, 2002
    Applicant: Northwestern University
    Inventors: Eva Redei, Fraser Aird, Leah Solberg, Claire Will
  • Corticotropin release inhibiting factor and methods of using same
    Publication number: 20020137885
    Abstract: The invention includes a substantially pure preparation of a corticotropin release inhibiting factor (CRIF) peptide having from three to twenty one or to twenty five contiguous amino acids contained within the amino acid sequence positioned between the fourth and fifth TRH sequence on a prepro-TRH protein.
    Type: Application
    Filed: February 19, 2002
    Publication date: September 26, 2002
    Applicant: Northwestern University
    Inventors: Eva Redei, Fraser Aird
  • Corticotropin release inhibiting factor and methods of using same
    Patent number: 6348571
    Abstract: The invention includes a substantially pure preparation of a corticotropin release inhibiting factor (CRIF) peptide having from three to twenty one or to twenty five contiguous amino acids contained within the amino acid sequence positioned between the fourth and fifth TRH sequence on a prepro-TRH protein.
    Type: Grant
    Filed: August 3, 1999
    Date of Patent: February 19, 2002
    Assignees: Northwestern University, The Trustees of the University of Pennsylvania
    Inventors: Eva Redei, Fraser Aird
  • Corticotropin release inhibiting factor and methods of using same for treating behavioral symptoms in an anxiety disorder
    Patent number: 6039956
    Abstract: The invention includes a substantially pure preparation of a peptide having corticotropin release inhibiting factor (CRIF) activity comprising at least three contiguous amino acids contained within the amino acid sequence positioned between the fourth and fifth thyrotropin releasing hormone (TRH) sequence on a prepro-TRH protein. The CRIF peptide further comprises the fourth uncleaved TRH portion of prepro-TRH positioned at the amino terminus of CRIF. Compositions, methods of diagnosis and methods of treating CRIF related diseases are also included in the invention.
    Type: Grant
    Filed: June 7, 1996
    Date of Patent: March 21, 2000
    Assignee: Pennsylvania, Trustees of the University of, The
    Inventors: Eva Redei, Fraser Aird, Peter A. Rittenhouse, Robert F. McGivern
  • Corticotropin release inhibiting factor and methods of using same
    Patent number: 5830866
    Abstract: The invention features a substantially pure preparation of a peptide having corticotropin release inhibiting factor (CRIF) activity comprising at least three contiguous amino acids contained within the amino acid sequence positioned between the fourth and fifth thyrotropin releasing hormone (TRH) sequence on a prepro-TRH protein. The CRIF peptide further comprises the fourth uncleaved TRH portion of prepro-TRH positioned at the amino terminus of CRIF. Compositions, methods of diagnosis and methods of treating CRIF related diseases are also included in the invention.
    Type: Grant
    Filed: September 8, 1995
    Date of Patent: November 3, 1998
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Eva Redei, Fraser Aird