Patents by Inventor Fraser Wilkes

Fraser Wilkes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Viral Assay Method
    Publication number: 20220042991
    Abstract: This invention relates to the rapid determination of the viral titer by contacting a solution comprising viral particles, such as lentiviral particles, comprising a heterologous envelope protein, such as VSV-G, with an immobilised receptor that binds to the envelope protein, and determining the binding of the viral particles to be immobilised receptor using surface plasmon resonance (SPR).
    Type: Application
    Filed: September 13, 2019
    Publication date: February 10, 2022
    Inventor: Fraser Wilkes
  • Vectors
    Publication number: 20090075370
    Abstract: The present invention relates to a polynucleotide comprising a nucleotide sequence encoding a retroviral gag protein, wherein the gag protein comprises a heterologous RNA binding domain capable of recognising a corresponding sequence in an RNA genome to facilitate packaging of the RNA genome into a retroviral vector particle.
    Type: Application
    Filed: June 13, 2008
    Publication date: March 19, 2009
    Inventors: Fraser Wilkes, James Miskin, Kyriacos Mitrophanous, Susan Kingsman
  • Viral Vectors
    Publication number: 20090017543
    Abstract: The present invention relates to an integration defective retroviral vector particle for gene therapy comprising a viral genome, wherein said vector particle is capable of infecting a mammalian target cell.
    Type: Application
    Filed: June 13, 2008
    Publication date: January 15, 2009
    Inventors: Fraser Wilkes, James Miskin, Kyriacos Mitrophanous, Susan Kingsman
  • Vectors
    Publication number: 20060281180
    Abstract: Provided is a lentiviral vector capable of delivering a nucleotide of interest (NOI) to a desired target site and wherein the NOI encodes the Factor VIII and the Factor VIII is expressed following delivery of the NOI to the desired target site.
    Type: Application
    Filed: April 25, 2006
    Publication date: December 14, 2006
    Inventors: Philippa Radcliffe, Fraser Wilkes, Susan Kingsman, Kyriacos Mitrophanous
  • Viral vector
    Publication number: 20050106559
    Abstract: Provided is a multicistronic retroviral vector genome having a first nucleic acid sequence upstream of at least one internal regulatory element, such that the level of genomic RNA available for packaging in the absence of rev, or a functional equivalent thereof, is increased.
    Type: Application
    Filed: May 7, 2004
    Publication date: May 19, 2005
    Inventors: Philippa Radcliffe, James Miskin, Fraser Wilkes, Kyriacos Mitrophanous, Susan Kingsman