Patents by Inventor Frauke DREYER

Frauke DREYER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pro-ADM for Prognosis of Trauma-Related Complications in Polytrauma
    Publication number: 20260056215
    Abstract: The invention relates to a method for the diagnosis, prognosis, prediction, risk assessment and/or risk stratification of a subsequent trauma-related complication in a polytrauma patient, comprising providing a sample of said patient, wherein the sample is isolated from the patient after the polytrauma, determining a level of proADM or fragment(s) thereof in said sample, wherein said level of proADM or fragment(s) thereof correlates with the likelihood of a subsequent trauma-related complication.
    Type: Application
    Filed: June 5, 2025
    Publication date: February 26, 2026
    Applicant: B.R.A.H.M.S GMBH
    Inventors: Darius WILSON, Aline PEHLA, Stefan EBMEYER, Frauke Dreyer
  • Pro-ADM for prognosis of trauma-related complications in polytrauma patients
    Patent number: 12560620
    Abstract: The invention relates to a method for the diagnosis, prognosis, prediction, risk assessment and/or risk stratification of a subsequent trauma-related complication in a polytrauma patient, comprising providing a sample of said patient, wherein the sample is isolated from the patient after the polytrauma, determining a level of pro-adrenomedullin (proADM) or fragment(s) thereof in said sample, wherein said level of pro-adrenomedullin (proADM) or fragment(s) thereof correlates with the likelihood of a subsequent trauma-related complication.
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: February 24, 2026
    Assignee: B.R.A.H.M.S GMBH
    Inventors: Darius Wilson, Aline Pehla, Stefan Ebmeyer, Frauke Dreyer
  • Pro-ADM for Prognosis of Trauma-Related Complications in Polytrauma Patients
    Publication number: 20210405070
    Abstract: The invention relates to a method for the diagnosis, prognosis, prediction, risk assessment and/or risk stratification of a subsequent trauma-related complication in a polytrauma patient, comprising providing a sample of said patient, wherein the sample is isolated from the patient after the polytrauma, determining a level of pro ADM or fragment(s) thereof in said sample, wherein said level of pro ADM or fragment(s) thereof correlates with the likelihood of a subsequent trauma-related complication
    Type: Application
    Filed: June 6, 2019
    Publication date: December 30, 2021
    Applicant: B.R.A.H.M.S GMBH
    Inventors: Darius Wilson, Aline Pehla, Stefan Ebmeyer, Frauke Dreyer
  • HISTONES AND/OR PROADM AS MARKERS INDICATING ORGAN DYSFUNCTION
    Publication number: 20190178897
    Abstract: The present invention relates to the diagnosis, prognosis, risk assessment, risk stratification, monitoring, therapy guidance and/or therapy control of organ dysfunction in a subject. The invention relates to a method that comprises determining a level of at least one histone, particularly H2B, H4, H2A and/or H3, in a sample of said subject and wherein said level of at least one histone is indicative of said organ dysfunction. Further, the invention relates to a method that comprises determining a level of proadrenomedullin (proADM), particularly midregional proadrenomedullin (MR-proADM), in a sample of said subject and wherein said level of proADM is indicative of said organ dysfunction. The invention further relates to kits for carrying out the methods of the invention.
    Type: Application
    Filed: August 8, 2017
    Publication date: June 13, 2019
    Inventors: Tim ZIERA, Frauke DREYER, Anne INCAMPS, Manne KROP, Pierre-Emmanuel CHARLES