Patents by Inventor Frauke Schimmöoller

Frauke Schimmöoller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of A? production by ?-secretase BACE2
    Patent number: 7183070
    Abstract: The present invention is based on the findings that BACE2, a homolog of ?-secretase BACE, is able to stimulate processing of APP in a non-amyloidogenic pathway, thereby suppressing the level of A?. Accordingly, the present invention provides methods and means for the identification and use of modulators of this unique activity of BACE2 to suppress A? production. The compounds identified using the methods and means provided herein may be used as potential candidates for the treatment of Alzheimer's disease and other neurological diseases by reducing ?-amyloid deposit formation.
    Type: Grant
    Filed: December 31, 2003
    Date of Patent: February 27, 2007
    Assignee: Scios Inc.
    Inventors: Barbara Cordell, Frauke Schimmöoller, Yu-Wang Liu, Diana Hom Quon